Báo cáo y học: "Computational biology touches all bases" pdf

... proteomic databases need to be acutely aware of data privacy, security and intellectual property http://genomebiology.com/2009/10/2/303 Genome BBiioollooggyy 2009, Volume 10, Issue 2, Article ... [http://www.iscb.org/cms_addon/ conferences/rocky08/agenda.php#allen] and poster abstracts are available at [http://www.iscb.org/cms_addon/conferences/ rocky08 /pdf/ RockyPosters2008Nov13 .pdf] . Her...

Ngày tải lên: 14/08/2014, 21:20

... development. Conclusions Analyses of massively parallel sequencing data, miRNA microarrays, small RNA blots, and target cleavage assays indicate that rapid and dynamic changes in gene expression and physiology are ... Wang JW, Yu N, Li CH, Luo B, Gou JY, Wang LJ, Chen XY: Control of plant trichome development by a cotton fiber MYB gene. Plant Cell 2004, 16:2323-2334. 10. Machado A, Wu Y, Yan...

Ngày tải lên: 09/08/2014, 20:20

... online at http://genomebiology.com/2008/9/9/R137 http://genomebiology.com/2008/9/9/R137 Genome Biology 2008, Volume 9, Issue 9, Article R137 Zhang et al. R137.2 Genome Biology 2008, 9:R137 unknown ... Another reason why peaks detected by ChIP-Seq may be undetected by ChIP- chip is that ChIP-Seq specific peaks are usually slightly shorter than similar fold-enrichment peaks found by both Ch...

Ngày tải lên: 14/08/2014, 20:22

... Paciorek (University of Tübingen, Germany) pre- 350.2 Genome Biology 2005, Volume 6, Issue 10, Article 350 Irish and Day http://genomebiology.com/2005/6/10/350 Genome Biology 2005, 6:350 Figure ... (towards the shoot tip)-abaxial (away from the shoot tip) polarity. Kiyotaka Okada (Kyoto University) described a microRNA (miRNA) sensor system developed to identify the localization of specif...

Ngày tải lên: 14/08/2014, 14:22

... conceptually much simpler. The future is likely to see many more mechanistically under- stood models of actual biological systems that rely on computational methods in systems biology for their construction. ... report CCoommppuuttaattiioonnaall mmooddeellss iinn ssyysstteemmss bbiioollooggyy Laurence Loewe* and Jane Hillston † Addresses: *Centre for Systems Biology at Edinburgh, School o...

Ngày tải lên: 14/08/2014, 21:20

... Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany and 2 Evolutionary Biology and Ecology, Department of Biology, University of York, York YO10 5YW, UK References 1. Krause ... potentially medical insights Human, chimpanzee Dinosaurs No, far too old Unique evolutionary lineage No close living relatives Prüfer et al. Genome Biology 2010, 11:R47 http://genomebiology.co...

Ngày tải lên: 09/08/2014, 20:22

... unclear how many studies fail to identify a causal locus by exome sequencing. Non-allelic heterogeneity, regulatory variation and structural variation underlying phenotypes all pose challenges for ... Pyrobayes: an improved base caller for SNP discovery in pyrosequences. Nat Methods 2008, 5:179-181. 17. Li R, Li Y, Fang X, Yang H, Wang J, Kristiansen K: SNP detection for massively pa...

Ngày tải lên: 09/08/2014, 23:20

... main methods currently used by clinicians to classify the severity of COPDFigure 1 The main methods currently used by clinicians to classify the severity of COPD. Respiratory Research 2009, 10:29 ... ana- lytical models now typically involve Bayesian inference approaches often starting with the hidden Markov model (HMM). This is essentially the simplest dynamic Bayesian network in which the s...

Ngày tải lên: 12/08/2014, 14:20

... spatial epidemiology of phytophthora root rot in fraser fir planta- tions. Phytopathology 2006, 90(9):1171-1180. 86. Mayton H, Aylor D, Fry W, Andrade-Piedra J: Quantifying the rate of release and escape of Phytophthora ... tuberosum against Phytophthora infestans. Mol Plant Microbe Interact 2007, 20(11):1346-1352. 18. Anand A, Uppalapati S, Ryu C, Allen S, Kang L, Tang Y, Mysore K: Sal- icy...

Ngày tải lên: 13/08/2014, 16:20

... an appropriate physiological environ- ment to study epithelial cyst development, function, and pathology. However, they too are complex dynamic sys- tems that have proven challenging to understand. The ... tightly must ISEA adhere to its operating principles before aspects of phenotype become measurably abnormal? We gained insight into plausible answers by systematically relaxing two, key ISE...

Ngày tải lên: 13/08/2014, 16:21