Báo cáo y học: " Epigenetic transmission of piRNAs through the female germline" docx

... progeny. The study of Brennecke et al. [5] thus has unequivocally documented the maternal transmission of piRNAs and their role in suppressing hybrid dysgenesis. In mice, transposon- specific piRNAs ... the paternally inherited transposons [6,7]. The genetically iden- tical progeny of the reciprocal cross is fertile, strongly suggest- ing transmission of epigenetic...

Ngày tải lên: 14/08/2014, 21:20

... HIV-1 evolution in vivo tracked by DNA heteroduplex mobility assays. J Virology 1994, 68: 6672-6683. 7. Shirly LR, Ross SA: Risk of transmission of human immunodeficiency virus by bite of an infected toddler. ... accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Acknowledgements All staffs of Department of Bi...

Ngày tải lên: 10/08/2014, 05:22

... due to the high probability that they could have HPV infection. The women were referred from the Obstetrical Service of the University of Caxias do Sul and by the Basic Health Units of the Single ... mother/NB in 16.3% (n = 8/49) of the pairs, characterizing the possibility of trans- mission of HPV-DNA intrauterine or during the delivery. The different types o...

Ngày tải lên: 12/08/2014, 04:21

... related cytopenias. The use of these agents is costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are ... with the latest combination therapy. However, existing data support therapy of the patient with compensated cirrhosis. Cirrhotic patients may tolerate therapy less well, given...

Ngày tải lên: 31/10/2012, 17:11

... closely with the crystal structure. There are other parts of the model that do not correlate with the crystal structure, in particular the region Fig. 4. A diagram of basal transcriptional activity ... mutant of mouse Q404H shows a marked decrease in basal activity as compared to both the wild-type and the other mutants of the mouse receptor (Fig. 4B). The human H407Q...

Ngày tải lên: 08/03/2014, 16:20

... procedure, according to the expression: F U ¼ y À y N Þ= y U À y N Þð6Þ where y N ¼ a 1 + a 2 T and y U ¼ b 1 + b 2 T represents the mean values of the y characteristic of the native and denatured ... Salamanca, Spain; 5 Department of Chemical Enzymology, Faculty of Chemistry, Moscow State University, Moscow, Russia The thermal stability of peroxidase from leav...

Ngày tải lên: 31/03/2014, 15:20

... costimulation orchestrates the clonal composition and features of the T cell response. Recently, many new costimulatory pathways have been discovered that influence the properties of T cell responses. The discovery of ... since the discovery of the TCR have shaped much of our understanding today regarding the immune system. After such a great amount of research on th...

Ngày tải lên: 09/08/2014, 01:24

... initially high- lighted in the T1D study as likely to contain the susceptibility gene [8]. A recent study of the IDDM8 region in T1D, how- ever, found no evidence of association, although they could not ... autoimmu- nity [1,2]. Recently convincing proof of this hypothesis has been provided by the association of the missense single nucle- otide polymorphism (SNP; rs2476601)...

Ngày tải lên: 09/08/2014, 08:22

... different YgfZ constructs to support the growth of the ΔygfZ E. coli strain in the presence of plumbagin. Plasmids were separately transformed into the ΔygfZ strain and assayed for the diameters of the ... that YgfZ is unlikely to be a part of an efflux/influx system. Furthermore, by comparing HPLC profiles of organic extract s prepared from the culture media of the...

Ngày tải lên: 10/08/2014, 05:21

... were expressed in terms of NIADD rat PRL-RP3 reference preparation. The sensitivity of the assay was 5 pg/tube. To analyze the variability of the assay, series of plasma of 10 replicates at 4 different ... from hemipituitary cultures [24]. Blockade of NO synthesis by the administration of N ω -nitro-L-arginine methyl ester (L- NAME), inhibits the preovulatory peak o...

Ngày tải lên: 10/08/2014, 09:20