Báo cáo y học: " Profiling RE1/REST-mediated histone modifications in the human genome" pps
Báo cáo y học: "Fast-evolving noncoding sequences in the human genome" pps
... power in our study but
mainly due to the fact that our analysis makes the explicit
assumption that the human lineage is significantly faster than
that of the chimpanzee, which is not the case in the ... the study con-
ducted by Pollard and coworkers. Interestingly, the most sig-
nificant ANC sequence in our analysis completely overlaps
with the most significant eleme...
Báo cáo y học: "otspots of homologous recombination in the human genome: not all homologous sequences are equal" ppsx
... recombination hotspots in the human
genome? Does it reflect only the positional preference of
double-stranded breaks by the recombination machinery? If
so, is this dictated by access to the DNA ... differences in the genetic back-
ground of the populations is not clear. The absence in the
chimpanzee of a hotspot in the region homologous to the
human recombinati...
Báo cáo y học: " Profiling RE1/REST-mediated histone modifications in the human genome" pps
... Shinkai Y: Set domain-con-
taining protein, G9a, is a novel lysine-preferring mammalian
histone methyltransferase with hyperactivity and specific
selectivity to lysines 9 and 27 of histone H3. J Biol ... appeared inextricably linked to gene expression,
since the decline in H3K4 methylations was also very notice-
able in the genes of our controls, so that the changes in these...
Báo cáo y học: " Overexpression of sICAM-1 in the Alveolar Epithelial " pps
... 12
sICAM-1 and LPS interact synergistically to increase
cytokine elaboration by AMs. Taken together, these
find ings imply a signi ficant, unique role for sICAM-1 in
modulating the inflammatory response ... sICAM-1 in the alveolus. We hypothesized that sICAM-1 in the alveolar space modulates the innate immune
response and alters the response to pulmonary infection.
Methods: Us...
Báo cáo y học: " Ethics and critical care in the new millennium" pps
... posed by the exciting therapeutics that draw us
to the field. In the coming months, Critical Care Forum will explore the ethical issues that so profoundly
affect our ability to provide meaningful ... over the world,
however, we need to talk more about how these advances
will affect the interests of the population as a whole;
otherwise we risk reaching a point a which marginal...
Báo cáo y học: " Clinical review: Scoring systems in the critically ill" ppsx
... resource
use. In this article we review the most commonly used
scoring systems in each of these three groups. We
examine the history of the development of the initial
major systems in each group, ... patients with a very short length of ICU
stay, and so on).
Second, the accuracy of any scoring system is highly
dependent on the quality of the input. To be used
correc...
Báo cáo y học: "A comprehensive transcript index of the human genome generated using microarrays and computational approaches" pdf
... considered
validated.
Analysis of tiling array data
The analysis of the tiling data has been described in detail by
Ying et al. [33]. Briefly, probes were separated into 15 kb win-
dows along the genome with ... and human upstream of the beta-actin gene. The tiling data readily detect all of the transcribed parts of the gene, but not the conserved
regulatory regions. The...
Báo cáo y học: "Profiling of cellular proteins in porcine reproductive and respiratory syndrome virus virions by proteomics analysis" pps
... not yet been reported in other studied envelope
viruses, namely, guanine nucleotide-binding proteins, tyrosine 3-monooxygenase/tryptophan 5-mon ooxygenase,
peroxiredoxin 1 and galectin-1 protein. ... protein interacts with IRS1
protein, suggesting a role in regulating insulin sensitiv-
ity. In response to DNA damage, proliferating cell
nuclear antigen protein is ubiquitinated and involv...
Báo cáo y học: "Complications after spacer implantation in the treatment of hip joint infections"
... (drain-
ing sinus, pneumonia, etc.). Despite the retrospective
design of our study and the limited possibility of in-
terpreting these findings and their causes, this rate
indicates that these ...
Despite the retrospective study design and the limited possibility of interpreting these find-
ings and their causes, this rate indicates that patients suffering from late hip joint inf...
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... costly and has not been studied rigorously in a
randomized controlled format to assess their value and
impact on efficacy of therapy although they are now
widely used in patients receiving interferon ... against
Cirrhosis), is a multicenter study of the potential benefit of
prolonged peginterferon therapy in mitigating the
progression of fibrotic liver disease. [8] In this s...
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