Báo cáo y học: "A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans" potx
Báo cáo y học: "A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans" potx
... 10:R7Open Access2009Needet al.Volume 10, Issue 1, Article R7Research A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large ... SNPs included in the original analysis.Additional data file 1Country of origin (or ancestry if US was country of origin and ancestry was provided) of the 611 European- American samples used in ... sparse availability of Central Asianpopulations makes interpretation of this proximity difficult.DiscussionThese analyses make clear that individuals with full Jewish ancestry are a genetically...
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Báo cáo y học: "Highly efficient genetic transduction of primary human synoviocytes with concentrated retroviral supernatant" pdf
... surgery. Stable genetic modifica-tion of primary synovial cells is an approach that may beuseful in defining the roles that specific signaling path-ways or inflammatory mediators play in the joint ... therapeutic approach to thetreatment of patients with inflammatory arthritis [2,3].Recombinant retroviral vectors are widely used in the labo-ratory, and in experimental clinical applications, ... fluorescentprotein transgene in transduced cells, and by analysis of viral RNA in retroviral supernatant.Concentration (100-fold) was achieved by centrifugation of viral supernatant for four hours, with...
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Báo cáo y học: "Defining the chromatin signature of inducible genes in T cells" pps
... H3K9ac and H3 antibodies and Affymetrixmouse promoter arrays (1.0R) and the data were analyzedusing the model-based analysis of tiling array (MAT) algo-rithm [30]. The promoter region of a gene ... variety of signals in many cell types may betagged in this manner at a very early stage of development.We have also found that our primary response gene set istagged with active chromatin in macrophages ... All authors read and approved thefinal manuscript.Additional data filesThe following additional data are available with the onlineversion of this paper: a figure of the density plot of basalexpression...
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Báo cáo y học: "Factors affecting the outcome of surgically treated non-iatrogenic traumatic cervical esophageal perforation: 28 years experience at a single center" docx
... female patients with a median age of 27.5 years. The type of injury was external trauma in 21 (70%) patients and endoluminal injury in the remaining 9 (30%) patients. The mechanism of injury was ... 21.5 days). Hospital stays weretwice as long in delayed patients, in those younger than18 years of age, and in those with a gunshot injury, and were significantly longer in patients with additional ... extraluminal injuries was 19%, and for endoluminal injuries was 11.1%. Mortality in patients treated within 24 h of sustaining injury was substantially less than in those for whom diagnosis and treatment...
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Báo cáo y học: " Evidence for genetic association of RORB with bipolar disorder" pptx
... patterns: RORB2 is found exclusively in the ret-ina and pineal gland, and RORB1 is found mainly in thecerebral cortex (particularly in layer IV and, to a lesserextent, layer V), thalamus, and ... School of Medicine, Indianapolis, IN, USA, 5Department of Psychiatry, UC San Diego, La Jolla, CA, USA and 6Pediatric Psychopharmacology Unit, Massachusetts General Hospital; Psychiatric Psychopharmacology ... 0.05 after1000 permutations.Association with genotyped SNPs and age-at-onset (AAO) of bipolar disorder was analyzed by performing a quanti-tative trait analysis using the option qfam in PLINK....
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Báo cáo y học: "Tracking the genetic imprints of lost Jewish tribes among the gene pool of Kuki-Chin-Mizo population of India" pptx
... population of IndiaBhaswar Maity, T Sitalaximi, R Trivedi and VK KashyapAddresses: National DNA Analysis Center, Central Forensic Science Laboratory, 30 Gorachand Road, Kolkata - 700014, India.Correspondence: ... analyses with Y- chromosomal binary markers revealed the male samples falling into Y- chromosomal haplogroups K*, O 2a, O 2a1 and O3e. These haplogroups are found predominantly in populations of East and ... revealed maternal and paternal lineages to have undergone different fates. Analyses at six Y- STR loci; DYS19, DYS388, DYS390, DYS391, DYS392 and DYS393 in 74 individuals reveals that all the alleles...
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Báo cáo Y học: The cold-active lipase of Pseudomonas fragi Heterologous expression, biochemical characterization and molecular modeling pdf
... GELCODE staining (Pierce). The protein concentra-tion was determined according to Bradford [19] with BSA asthe standard.Lipase activity was determined in a pH-stat assay bytitrating fatty acids ... secreted by a signal peptide-independent pathway and calls for furtherinvestigation on this subject.Enzyme activity and specificity In the standard tricaprylin hydrolysis assay, rPFL displayedhighest ... chain.The Ca ion is coordinated also by the backbone carbonyl groups of H266 and R269. Bond distances and angles involving the metal atom and the coordinating amino acids are very similar to the...
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Báo cáo y học: "Phase I safety study of 0.5% PRO 2000 vaginal Gel among HIV un-infected women in Pune, India" potx
... of Allergy and Infectious Diseases, National Institutes of Health and 6The National Institute of Allergy and Infectious Diseases, National Institutes of Health and Johns Hopkins University ... containing single dose tubes of 0.5% PRO 2000 Gel and an equal number of calibratedpolyethylene vaginal applicators. They were asked toapply a 2 gm dose of the product intra-vaginally twicedaily ... We also acknowledge Fogarty International Research Collaboration Award (FIRCA) for training and thank Dr. R. C. Bollinger, Infectious Diseases & International Health and other staff at...
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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
... paralog HIP1-R, subunits of clathrin-associated adaptor protein (AP) complexAP 2A1 and AP 2A2 , clathrin heavy chain 1 (CLH1), and clathrin heavy chain 2 (CLH2), clathrin lightchain A (CLTA), and ... transcriptionCorrespondenceN. P. Bhattacharyya, Crystallography and Molecular Biology Division and StructuralGenomics Section, Saha Institute of NuclearPhysics, 1 ⁄ AF Bidhan Nagar, Kolkata700 064, IndiaFax: +91 033 ... toxicity.J Neurosci 27, 11056–11064.46 Majumder P, Raychaudhuri S, Chattopadhyay B &Bhattacharyya NP (2007) Increased caspase-2, calpainactivations and decreased mitochondrial complex IIactivity...
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báo cáo hóa học:" Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro" pdf
... T, Suhara Y, Eguchi C, Ishi-hara T, Nonaka I, Ozawa E, Sugita H: Immunostaining of skeletal and cardiac muscle surface membrane with antibody againstDuchenne muscular dystrophy peptide. Nature ... São Paulo, Brazil and 2Fetal Medicine Institute of São Paulo, São Paulo, BrazilEmail: Tatiana Jazedje - tatiana@ib.usp.br; Mariane Secco - marianesecco@usp.br; Natássia M Vieira - natassia@usp.br; ... 109:235-242.17. Ishikawa H, Nakao K, Matsumoto K, Ichikawa T, Hamasaki K, NakataK, Eguchi K: Antiangiogenic gene therapy for hepatocellularcarcinoma using angiostatin gene. Hepatology 2003,37(3):696-704.18....
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