Báo cáo y học: "Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes" pot

... work is properly cited. Ribosomal protein pseudogenes& lt;p>An analysis of ribosomal protein pseudogenes in the four mammalian genomes reveals no correlation between number of pseudogenes and ... reports indicated there are exactly 80 ribosomal protein genes encoded by the human genome. Conclusions: Our analysis indicates that processed ribosomal protein...

Ngày tải lên: 14/08/2014, 21:20

... within non -protein- coding genes (1,653 out of 896,471). In contrast, we found a 0.06% rate of exonization within protein coding genes (506 out of 888,768) and 0.08% (722 out of 942,164) in non -protein- coding ... cases in which the exonizations were constitutive and not symmetric, they were introduced within hypothetical proteins. In these cases, these are either not bon...

Ngày tải lên: 14/08/2014, 07:21

... these findings and to understand the complexity of the emerging diversity of HIV in this region of high diversity. Finally, although higher frequencies of drug resistance in patients harboring X4 ... are becoming increasingly attractive as monitoring tools. Here we report a comparative analysis of viral tropism of strains circulating in Cameroon where diverse and emerging...

Ngày tải lên: 10/08/2014, 05:21

... yeast proteins involved in protein- protein interactions found using yeast two-hybrid (Y2 H) assay, protein epitope-tag affinity purification/mass spectrometry (AP-MS) and protein microarray ... of yeast WW domain -protein interactions We used protein microarrays to generate a protein interaction map of yeast WW domain-containing proteins. The microar- rays were constructed b...

Ngày tải lên: 14/08/2014, 16:21

... maximizing the potency of a given inhibitor, but invariably ignore factors critical for understanding drug action, including cell permeability and the potential interaction/inhibition of other proteins in ... similarity clustered together (Figure 2c): rapamycin, calyculin A and wiskostatin. The similar- ity in these profiles resulted from inhibition of strains deleted for genes invo...

Ngày tải lên: 09/08/2014, 20:21

... are indicated by their accession number. Table 2 Clinical status, subgenotype and genotype of HBV strains according to the genotyping method Genotype determined using Sample Clinical status PCR- RFLP TSP- PCR Sequencing ... transition to subgenotype D1 in the East of the continent. HBV genetic variability may lead to wrong results in rapid genotyping methods and sequence analysis is...

Ngày tải lên: 12/08/2014, 02:20

... path- ways were manually curated from the published literature for genes involved in insulin signaling. Two hundred and forty- four gene sets were obtained by querying all the pathways available ... We Significantly differentially regulated pathways identified by GSEA analysisFigure 1 Significantly differentially regulated pathways identified by GSEA analysis. The histogram represents th...

Ngày tải lên: 14/08/2014, 14:21

... accurate measure of Hsf 'binding affinity' or that simple binding site prediction is not a reliable way of identifying genuine HSEs. Comparative analysis Two genome-wide studies in the budding yeast ... Briefly, we used a construct (MBP-dHsf [25], kindly provided by J. Lis, Cornell University) to produce a fusion protein containing the first 691 amino acids of Hsf fused...

Ngày tải lên: 14/08/2014, 14:21

... in this module describes activation of Shc that is dependent on Fyn (Proto-oncogene tyrosine -protein kinase Fyn), Cav1 and Integrin (ITGB1) (Figure 5a). Both the transcript and protein data indicate ... K: Pathway logic: symbolic analysis of biological signaling. Pac Symp Biocomput 2002:400-412. 36. Talcott C, Eker S, Knapp M, Lincoln P, Laderoute K: Pathway logic modeling of p...

Ngày tải lên: 14/08/2014, 21:20

... only a few P-SMAD1/5-positive cells were visible, mostly in the lining layer of the synovium (Figure 1b). With increasing severity, characterized by infiltration of inflammatory cells and synovial ... BMP7 staining in the lining layer of synovium (Figure 5b) and in superficial chondrocytes in the articular cartilage (Figure 5b). With increasing severity (Figure 5c,e), BMP7 posit...

Ngày tải lên: 09/08/2014, 13:22