Báo cáo y học: " Regulating highly dynamic unstructured proteins and their coding mRNAs" ppt

... complexity with consequent highly dynamic protein conformation. As Gsponer et al. [4] show, IUPs have evolved to be under tight regulation to minimize their own half-lives and those of their mRNAs. Yet, ... vital functions [2], and simple sequences apparently evolve more rapidly than those of highly structured proteins [3]. Living systems have either adapted to IUPs very early...

Ngày tải lên: 14/08/2014, 21:20

... supplied by R. Cerione, Cornell University, Ithaca, NY, USA, and A. Bender, Indiana University, Blooming- ton, USA, respectively, and purified by affinity chromatog- raphy as previously described ... homology and 63% similarity and are members of a family of cytotoxins known as the large clostridial cytotoxins that also contains the lethal toxin from C. sordellii and the a-toxin from...

Ngày tải lên: 08/03/2014, 22:20

... prevalence, and treatment of anxiety and depressive disorders in Pakistan: a systematic review. BMJ 2004, 328:794. 15. Hays LR, Cheever T, Patel P: Medical students suicide, 1989– 1994. Am J Psychiatry ... staff Relationship with colleagueDomestic responsibilityFamily FinancialHeavy workloadNil Annals of General Psychiatry 2009, 8:8 http://www.annals-general-psychiatry.com/content/8/1/8 P...

Ngày tải lên: 08/08/2014, 23:21

... SERT density and ligand binding affinity, respectively, whereas V max and K m values of [ 3 H]Serotonin uptake were taken as estimates of SERT rate and affinity, respectively. A very interesting ... any statistically significant variations. Symptom severity score (tiredness, tender points index and Fibromyalgia Impact Questionnaire) were negatively correlated with B max and with V...

Ngày tải lên: 09/08/2014, 08:22

... osteoblastic activity. The sensitivity is 0.7 U/l, and the intra-assay and inter- assay coefficients of variation at 28 U/l were 3.3% and 7.9%, respectively [29]. For osteocalcin, we used the US Food and Drug ... radiography (weight-bearing fluoroscopic posteroanterior (PA), lateral, and skyline views), and if on any of these views they had a definite osteophyte in the sympto- mat...

Ngày tải lên: 09/08/2014, 13:21

... for rice, and 95% of them used it every year. They spread the soil in paddy fields or upland rice fields in May and June before rice planting. Mound soil was not used as fertilizer for any crop ... from their mounds and surrounding areas and identified. Twenty villagers were interviewed on their use of termites and their mounds in the village. Sixty-three mounds were measured...

Ngày tải lên: 10/08/2014, 09:22

... expression and any of the YSR syndromes, while young women with anxious-depression and inter- nalizing syndrome were more likely to report serious suicidal expression. This picture is slightly different from ... complaints and thought problems. Among the young women, heath maintenance/physical fitness inversely correla ted with all YSR syn dromes and, unlike young men, total life skil...

Ngày tải lên: 11/08/2014, 15:22

... study was supported by the Department of Psychiatry and Cognitive Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences and also by a Grant-in-Aid from the Ministry of ... anxiety disorders and Cluster A and C personal- ity disorders were included, when these symptoms abated sufficiently to allow them to attend the group CBT sessions regularly, judged by the...

Ngày tải lên: 11/08/2014, 16:22

... Jeang, Ned Landau, Hinh Ly, and Ron Swanstrom. References 1. Swanstrom R: Andrew Kaplan (1959–2006): remembering a friend and a colleague. Retrovirology 2006, 3:61. 2. Telesnitsky A: The Andy Kaplan ... Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Retrovirology 2007, 4:3 http://www.retrovirology.co...

Ngày tải lên: 13/08/2014, 09:20

... practically binding, and society will need to question the extent to which doctors have to endanger their lives for public good. There will inevitably be reciprocal demands on society by such physicians ... likely to be more beneficial. Risk does not always respond to claims of fairness and is unfortunately encountered by both choice and chance [14]. Professional and institutional s...

Ngày tải lên: 13/08/2014, 11:22