Báo cáo y học: "Identifying protein-coding genes in genomic sequences" ppt

... α chain, TNF-α, and lymphotoxin-α genes and risk of asthma in Hong Kong Chinese adults. Int Arch Allery Immunol 2007, 144(2):114-122. 39. Sun J, Yu XH, Chen Y, Zhao HL, Yu JB, Zhou Y, Yi LY, Zhang ... between interleukin-1 beta gene polymorphism and childhood asthma (Chinese). Shi Yong Er Ke Lin Chuang Za Zhi 2006, 21(16):1074-1075. 81. Gao JM, Lin YG, Qiu CC, Liu YW, Ma Y, Liu Y, Zhu...

Ngày tải lên: 12/08/2014, 11:22

... associated with insulin ("insulin action", "insulin resistance", "insulin sensitivity", "hyperinsulinemia" and "hyperinsulinaemia"). Other reference ... +-2 ! ! ! + hyperinsulinaemia ! ! ! + 8 ! ! ! +-12 + hyperinsulinemia 1 7 ! ! ! ! ! ! + 14 + insulinsensitivity ! ! ! ! ! ! ! + 10 + insulinresistance ! ! ! ! ! + insulinaction ! !...

Ngày tải lên: 13/08/2014, 16:21

... domains yield important insights into repeat evolution, in the same way that multidomain protein organi- zation yields insights into protein evolution [15,16]. However, while the study of protein ... domains is only approximate. Determining the exact boundaries of repeat domains is a challenging problem, similar to the diffi- culty in defining the boundaries of protein domains. The ambigu...

Ngày tải lên: 14/08/2014, 16:20

... Hydrogen bonding modulates binding of exogenous ligands in a myoglobin proximal cavity mutant. Biochemistry 38, 11086–11092. 30. Franzen, S. (2002) Carbonmonoxy rebinding kinetics in h93g myoglobin: ... proximal cavity mutant of Hb has recently demonstrated the key role of the proximal histidine in the cooperativity of quaternary structure change in response to ligand binding [4]. Str...

Ngày tải lên: 08/03/2014, 16:20

... cardio- vascular disease in systemic lupus erythematosus or rheuma- toid arthritis on postmortem examination [3]. Arteritis remains a possibility, however, in PMR and GCA. A study of biopsy- proven GCA ... demonstrated no increase in carotid intimal thickness, so atherosclerosis alone does not explain the increased cardiovascular mortality seen in GCA [9]. Although Warrington and coll...

Ngày tải lên: 09/08/2014, 14:20

... LOC388720are involved in the KEGG (Kyoto Encyclopaedia of Genes and Genomes) ribosome pathway. RPS6 is also involved in the insulin signalling and the mTOR signalling pathway. MCM3 and VIM are involved in ... NME2 negatively reg- ulates Rho activity through interactions with other proteins involved in the Rho pathway [22]. In embryonic mouse lungs, the inhibition of the Rho pathwa...

Ngày tải lên: 12/08/2014, 14:20

... rebounding. Drugs given through the enteral route may be poorly absorbed, which again may lead to drug resistance. By inhibiting cytochrome P450 3A4 the drugs interfere with the metabolism of many ... in the respiratory chain and life-threatening lactic acidosis. Pancreatitis may be Commentary Continuing HIV therapy in the ICU Neil Soni and Anton Pozniak Chelsea & Westminster NHS Trus...

Ngày tải lên: 12/08/2014, 18:21

... oxidative stress in children and that antioxidant therapy may be useful in the future. Introduction Anti-inflammatory drugs such as inhaled corticosteroids now are the mainstay of treatment in childhood ... airway inflammation using tradi- tional invasive procedures is not feasible in children. Bronchial biopsy is invasive and non-invasive tests such as spirometry do not represent the...

Ngày tải lên: 12/08/2014, 18:21

... Pulmonary artery remodeling and pulmonary hypertension after exposure to hyperoxia for 7 days. A morphometric and hemodynamic study. Am J Pathol 1984, 117:273-285. 20. Rich S: Primary pulmonary hypertension. ... time point at which balloon inflation takes place can only be identified by a clear modification in the PAP curve. In our analysis, we accepted only those curves in which a clea...

Ngày tải lên: 12/08/2014, 20:21

... decades. Interestingly, critical illness has the potential to become a key testing ground and field of application for these emerging modeling techniques, given the increasing availability of point-of-care ... biomarker profiles should be interpreted remain open fields of inquiry. In this regard, the development of data-driven models that ‘explain’ the dynamics of markers of septic physiolo...

Ngày tải lên: 13/08/2014, 08:20