Báo cáo y học: "Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo" ppsx

Báo cáo y học: "Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo" ppsx

Báo cáo y học: "Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo" ppsx

... multi- ple signaling pathways, the ability to detect the activation sta- tus of individual pathways within a complex network of other pathways in the cell is of paramount importance. In this man- ner, ... pathway activation in mammary glands expressing activated Ras for 96 h and in mammary tumors induced by chronic Ras activation. (b) Western analysis showing incr...
Ngày tải lên : 14/08/2014, 21:20
  • 11
  • 262
  • 0
Báo cáo y học: "Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus" pot

Báo cáo y học: "Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus" pot

... standard curve. The analytical reproducibility of all aRibP assays was evaluated by repeated testing of two serum samples (10 determinations each) in the same run, giving intraas- say coefficients of variation ... signifi- cantly lower lymphocytes than aRibP R 0 - lupus patients. Interestingly, a P0-like protein is also detectable in the plasma membranes of different cells, includ...
Ngày tải lên : 12/08/2014, 15:22
  • 11
  • 415
  • 0
Báo cáo y học: "Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitus" ppsx

Báo cáo y học: "Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitus" ppsx

... for their tinnitus. Tinnitus matching is performed by presenting sounds to the ear in which the tinnitus is not perceived, and both tinnitus pitch and tinnitus intensity (above hearing threshold) ... perceived tinnitus. Technical investigations include MRI of the brain and posterior fossa, pure tone and speech audiometry, Auditory Brainstem Response (ABR) and tympanometry. Assess...
Ngày tải lên : 08/08/2014, 16:23
  • 5
  • 432
  • 0
Báo cáo y học: "Regulating the immune system: the induction of regulatory T cells in the periphery Jane H Buckner1 and Steven F Ziegler2" pot

Báo cáo y học: "Regulating the immune system: the induction of regulatory T cells in the periphery Jane H Buckner1 and Steven F Ziegler2" pot

... expectancy, thymic involution, and antigen exposures, the development of CD4 + CD25 + T R cells may occur in the periphery in man. Induction of CD4 + CD25 + T R cells in the periphery The induction of ... capable of directly generating Tr1 cells in vitro and in vivo, and may represent a naturally occurring dendritic cell subset involved in eliciting tolerance in vivo [41...
Ngày tải lên : 09/08/2014, 01:24
  • 8
  • 478
  • 0
Báo cáo y học: "Smoking and nicotine exposure delay development of collagen-induced arthritis in mice" pptx

Báo cáo y học: "Smoking and nicotine exposure delay development of collagen-induced arthritis in mice" pptx

... disease severity of CIA in mice. In our study we used a well-established model of smoke-induced emphysema in mice [20,21]. In the course of this model, mice develop a progressive infiltration of inflammatory ... Therapy Vol 11 No 3 Lindblad et al. Page 2 of 8 (page number not for citation purposes) the stimulating effect of nicotine on collagen and gly- cosaminoglycan synt...
Ngày tải lên : 09/08/2014, 14:21
  • 8
  • 339
  • 0
Báo cáo y học: "Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study" pptx

Báo cáo y học: "Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study" pptx

... disabling dis- ease are likely to lead a less active lifestyle, resulting in increased obesity and alterations in the lipid profile [42,43]. One of the most interesting findings from this study, ... WHO definition. This phenomenon may be explained by differences in the compo- nents and cut-off values used in the definitions. The WHO is the only definition to include albumin/creatini...
Ngày tải lên : 09/08/2014, 14:22
  • 10
  • 499
  • 0
Báo cáo y học: " A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk" pptx

Báo cáo y học: " A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk" pptx

... chemical-genetics system to modulate the activity of a protein kinase by mutating an amino acid residue in its ATP-binding pocket (the ‘gate- keeper’ residue), allowing the resulting kinase - often called ... essentially all cellular processes, including the DNA-damage response (DDR). Key aspects of the DDR are the slow- ing or stopping of cell cycle progression by DNA- damage checkpo...
Ngày tải lên : 09/08/2014, 23:20
  • 14
  • 378
  • 0
Báo cáo y học: "Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan" potx

Báo cáo y học: "Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan" potx

... methy- lated- and u nmethylated-specific primers, respectively [23]. Flow Cytometry for DNA Ploidy 703 of 1,173 tumors were available to examine the status of DNA ploidy using flow cytometry by ... Molecular karyotype profiling of the two subtypes of sporadic CRCs revealed significant differences in the extent and distr ibution of CN altera- tions in the cancer genome. Combining...
Ngày tải lên : 10/08/2014, 05:21
  • 11
  • 344
  • 0
Báo cáo y học: " Developing quality indicators for the care of HIVinfected pregnant women in the Dutch Caribbea" pot

Báo cáo y học: " Developing quality indicators for the care of HIVinfected pregnant women in the Dutch Caribbea" pot

... potential indicator by defining its numerator and denominator. Phase 2: Applicability test of potential quality indicators Before the indicator set is u sed in a specific setting, its applicability in ... similarity to the quality indicators in our study namely indicator 1 (’HIV screen- ing in all pregnant women’), indicator 5 (’ preconcepti on counselling’ ), indicator 9 (’antiretr...
Ngày tải lên : 10/08/2014, 05:22
  • 9
  • 320
  • 0
Báo cáo y học: "Simvastatin protects bladder and renal functions following spinal cord injury in rats." ppsx

Báo cáo y học: "Simvastatin protects bladder and renal functions following spinal cord injury in rats." ppsx

... often results not only in paralysis but also in the loss of sensation and reflexes below the point of injury, such as bowel and blad- der control. Dysfunction of the urinary system is one of ... pathophysiology of bladder dysfunction in SCI patients is significant. We investigated the pathophysiology of spinal bladder dysfunction in a rat contusion model of SCI. Con...
Ngày tải lên : 11/08/2014, 03:20
  • 10
  • 371
  • 0