Báo cáo y học: "Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites" doc

... 1 Gel-loading regimen Gel TP1 TP2 TP3 TP4 Pool gel1 Cy3 Cy5 Cy2 gel2 Cy5 Cy3 Cy2 gel3 Cy3 Cy5 Cy2 gel4 Cy5 Cy3 Cy2 gel5 Cy3 Cy5 Cy2 gel6 Cy3 Cy5 Cy2 gel7 Cy5 Cy3 Cy2 gel8 Cy3 Cy5 Cy2 Each two-dimensional ... Immobiline DryStrip [GE Healthcare]), and in the second dimension on an 11% polyacrylamide gel. Proteins /protein isoforms identified by tandem mass spectrometry are highlighted in...

Ngày tải lên: 14/08/2014, 21:20

... function and pathway analyses were carried out by searching the National Centre for Biotechnology Information database [52] and by using various analysis programs includ- ing OntoExpress [53] and ... with a large family of ligands, cognate receptors and intracellular signalling molecules involved in the pathway, exerting both stimulatory and inhibitory effects on bone remod- ellin...

Ngày tải lên: 09/08/2014, 10:21

... antithro mbin III (synonymous with SERPINC1), and inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4; synonymous with inter-alpha-trypsin inhibitor family heavy chain-related protein, IHRP), ... factor-binding protein 4; IHRP: inter-alpha-trypsin inhibitor family heavy chain-related protein; IPI: international Protein Index; ITIH4: inter-alpha-trypsin inhibitor heavy chain H4; iTRAQ:...

Ngày tải lên: 10/08/2014, 21:23

... time point post infec- tion. Contrastingly, genes coding for ribosomal proteins and other proteins involved in protein translation were down-regulated at early stages of (4 hpi) IBCDC-RG7 infection ... differential expression pattern and were mainly involved in Cytokine-cytokine receptor interaction, Toll like-receptor mediated signal- ing and p53 signaling pathway [Figure S1 (A...

Ngày tải lên: 12/08/2014, 01:21

... rich (Sfpq), oxysterol binding protein- like 3 (Osbpl3), RanBP-type and C3HC4-type zinc finger containing 1 (Rbck1), myeloid/lym- phoid or mixed-lineage leukemia 1 (Mll1) and Rho family GTPase 2 (Rnd2). ... genes in this ranking list are heat shock 70 kDa protein 5 (Hspa5), myelin basic protein (Mbp), calcium/calmodulin-dependent protein kinase IG (Camk1g), Per2, Dbp, splicing fa...

Ngày tải lên: 14/08/2014, 08:20

... the determination of creatine kinase in blood modified by the inclusion of EDTA. The Committee on Enzymes of the Scandinavian Society for Clinical Chemistry and Clinical Physiology (SCE). Scand J Clin ... supplied all essential amino acids to maximise the increase in protein synthesis during recovery. Conclusion In summary, the major finding of this investigation was that whey prot...

Ngày tải lên: 11/08/2014, 23:21

... raltegravir, to distinguish between integrated and non-integrated HIV-1 cDNA in infected primary PBL, macrophages, and ahumanCD4 + cell line. We detected HIV-1 integration by utilizing a well-defined two-step ... u sing two different virus strains. By using these primary cell subsets, we show that this method can be useful in precisely moni- toring the level of integration in labora...

Ngày tải lên: 12/08/2014, 02:20

... the emerging inflammation. The infiltration of inflammatory cells into the joints is believed to initiate the activation of synovial cells and sequent hyperplasia of the synovium lining, which ... microarray gene expression profiling of rats with AA has previously been reported. Therefore, we undertook this important and timely study of the gene expression analysis in AA....

Ngày tải lên: 12/08/2014, 18:20

... proteome revealed antibody responses to all HIV proteins including the HIV reverse transcriptase and minor accessory proteins such as Rev and Vif [26]. To determine if LIPS could detect antibody responses ... carriers. This discrepancy may be due to the increased sensitivity in detecting anti-Tax antibodies in the LIPS format. Previously, molecular mimicry against HTLV-I proteins was...

Ngày tải lên: 13/08/2014, 05:21

... history of chemotherapy or radiotherapy. Immunohistochemistr y was used to assess ERCC1 expression in pretreatment biopsy specimens from paraffin blocks. Clinical parameters, including smoking, ... mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J...

Ngày tải lên: 18/06/2014, 19:20