Báo cáo y học: " FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease" pdf

... underlying microarray study results. Conclusion This study demonstrates that highly differentially expressed genes are more likely to harbor disease -associated variants. FitSNPs successfully distinguished ... Article R170 Research FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease Rong Chen *†‡...

Ngày tải lên: 14/08/2014, 21:20

... its potential ability to find genes that have not traditionally been involved with can- cer, as they may represent new avenues for cancer cell biology and, more importantly, therapeutic intervention. Additional ... only about 5 seconds. Since the number of gene pairs and thus the computing time grows quadratically with the number of genes, the analysis of a roughly quintupled Aff...

Ngày tải lên: 14/08/2014, 14:22

... means to identify differentially expressed genes. Effect of gene-specific knockdown on the accumulation of BaMV To investigate the roles of the differentially expressed genes identified by cDNA-AFLP ... 5, an d 7 days post inoculation, to identify differentially expressed genes in N. benthamiana plants following infection with BaMV. To avoid genomic contamination o...

Ngày tải lên: 11/08/2014, 11:21

... objective of this study was to identify differentially expressed genes associated with the semi gametic genotype using microarray analysi s in order to gain insight into the underlying molecular mechanism of ... associated with semigamy in cotton. In this study, over 2,000 diff erentially expressed gene s associated with semigamy were identified with 127 of those ge...

Ngày tải lên: 11/08/2014, 11:21

... systemic lupus erythematosus (14%), systemic sclerosis (13%), polymyositis/dermatomyositis (14%), and SS Table 3 Correlations with clinical and laboratory parameters of anti-CCP antibody-positive and ... 1.475 to 74.870; P = 0.010). Conclusion Only a minority of patients with pSS are anti-CCP- positive, which seems to be closely associated with the prevalence of synovitis. Anti-...

Ngày tải lên: 09/08/2014, 10:23

... analysis by flow cytometry (FACSCalibur ® ; BD Biosciences) using CellQuest Pro ® soft- ware (BD Biosciences). Cell culture and cytokine assays Peritoneal macrophages were obtained 4 days after ... also favor an immunomodulatory environ- ment by the release of anti-inflammatory cytokines during apoptotic cell uptake. Such immunomodulatory milieu consists mainly of TGFβ and IL-10 [5-7]. BSA:...

Ngày tải lên: 09/08/2014, 14:22

... a 30-year-old Japanese man who was trans- ferred to the emergency depart ment with d iabetic ketoa- cidosis and was initially diagnosed with type 1 diabetes three years prior to this study. He ... Rosenstock J, Yki-Järvinen H, Cefalu WT, Chen Y, Luo E, Musser B, Andryuk PJ, Ling Y, Kaufman KD, Amatruda JM, Engel SS, Katz L: Efficacy and safety of sitagliptin when added to insulin...

Ngày tải lên: 11/08/2014, 00:23

... Therapy with those of peo- ple referred to an activity group, we will be able to com- pare levels of engagement with these different types of groups and to explore whether any benefit associated with ... Art Therapy is associated with improved global functioning at 24 months compared to referral to attention control treatment or standard care alone. ii) Referral to gro...

Ngày tải lên: 11/08/2014, 16:22

... Department of Ophthalmology, The New York Eye and Ear Infirmary, New York, NY, USA, 2 Einhorn Clinical Research Center, The New York Eye and Ear Infirmary, New York, NY, USA, 3 Glaucoma Service, ... Ophthalmology, The New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY 10003, USA, 4 Manhattan Eye, Ear and Throat Hospital, New York, NY, USA, 5 New York University School o...

Ngày tải lên: 11/08/2014, 19:21

... [31]). Flow cytometry and histology analyses confirmed that the increased volume results from accumulation of lymphatic fluid, associated with the expression of LYVE 1+, a lymph spe- cific hylauronic ... ILN. Afferent lymphatic flow to ipsilateral lymph nodes is associated with knee synovitis To assess the direct association between knee synovitis and afferent lymphatic flow to...

Ngày tải lên: 12/08/2014, 17:22