Báo cáo y học: " Whole genome transcriptome polymorphisms in Arabidopsis thaliana" ppt

... § Exonic splicing analysis using exon intensity corrected by gene mean. ¶ Exonic splicing analysis using exon intensity corrected by gene median. ¥ Exonic splicing analysis using splicing index. http://genomebiology.com/2008/9/11/R165 ... located in the thylakoid lumen functioned in proteoly- sis or protein folding, presumably to repair or maintain the photosynthesis apparatus (Table...

Ngày tải lên: 14/08/2014, 21:20

... by indexing and deploying obligate pathogen effectors” [40] . The value of being able to corre- late many different phenotypes, including genome- wide phenotypes, has already been beautifully ... Moreover, as flowering plants only appeared about 100 million years ago, they are all relatively closely related. Indeed, key aspects of plant physiology such as flowering are highly conserved betwe...

Ngày tải lên: 14/08/2014, 21:20

... replicates, with mutations in the glyc- erol kinase and RNA polymerase genes present in most evolved strains. Experiments showed that a single mutation in glycerol kinase or RNA polymerase genes could ... the RNA polymerase. Conclusions: The 82 base-pair deletion found in the rph-pyrE operon of many endpoints may function to relieve a pyrimidine biosynthesis defect present in MG1655...

Ngày tải lên: 09/08/2014, 20:20

... PF11_0255 † Involved in decapping Lsm2 PFE1020w Involved in decapping Lsm3 PF08_0049 Involved in decapping Lsm4 PF11_0524 Involved in decapping Lsm5 PF14_0411 Involved in decapping Lsm6 PF13_0142 Involved ... Interestingly, many of these categories are the same as those identified in this study, including ribosomal proteins, proteins involved in energy metabolism, and proteins i...

Ngày tải lên: 14/08/2014, 07:22

... approximately 1.5 Mb to 6 Mb, the chromosome is dominated by type I SNPs in the reference strains (as indicated by the straight grey line) and correspondingly there are very few polymorphisms ... family domain containing 4.325 0.010 <P < 0.025 X (II) Me49 (II) 42.m07434 Hypothetical Infinity 0.010 <P < 0.025 X (II) VEG (III) 42.m03570 LytB domain-containing protein Infinity 0...

Ngày tải lên: 14/08/2014, 21:20

... hetero- zygous genotyping alleles. For 10 of the remaining 46 differ- ing positions, a heterozygote call was made by MAQ whereas the genotyping array only showed the reference allele, indi- cating ... heterozygote under-call by MAQ (array based genotype heterozygote, MAQ based genotype homozygote). Seq-het>GT-hom indicates a possible heterozygote under-call by the array (array-based gen...

Ngày tải lên: 14/08/2014, 21:21

... protein–coupled receptor superfamily, which contains 413 amino acids and was cloned in 1987. 4 Since then, several single nucleotide polymorphisms (SNPs) have been identified, including Gly16, ... was accomplished by retrospectively examining three independent clinical trials using ICS as the primary therapeutic intervention. Variation in one gene, corticotrophin-releasing hor- mone rec...

Ngày tải lên: 08/08/2014, 21:20

... primer). Results and discussion In marked contrast to previous findings, no polymorphic alleles (neither thymine at position 40 nor cytosine at position 1,400) were detected in any of the individuals tested. ... sur- prising because both positions were highly polymorphic in the original publications. In those publications, heterozygosity at position 40 (V14M) was detected in four in...

Ngày tải lên: 09/08/2014, 07:20

... genotyped using the TaqMan SNP Genotyping Assay (Applied Biosystems, Foster City, CA, USA), and association was examined in 308 SLE patients and 306 healthy individuals. Statistical analysis Association ... participated in the first screening using Illumina Gold- enGate assay (with AK), including tag SNP selection, geno- typing, and statistical analysis. JO carried out statistical analysi...

Ngày tải lên: 09/08/2014, 13:22

... MAF = minor allele frequency; Ref = reference; SNP = single nucleotide polymorphism. a combination of initial finding and replication (when available) in the cited study; effects from minor allele. b ... RA and 303 OA samples in a case-control setting. Six SNPs were genotyped using TaqMan assays. HLA-DRB1 alleles were determined by employing site- specific polymerase chain reaction (PCR)...

Ngày tải lên: 09/08/2014, 14:20