Báo cáo y học: "Do we use the appropriate controls for the identification of informative methylation markers for early cancer detection" doc

... an opportunity for comprehensive DNA- methylation profiling of human cancers with the eventual aim of identifying selec- tive markers for early detection [3,4]. Including appropriate control (cancer- free) ... type from healthy individuals, are conceiv- able controls. The former are extensively used as controls in many laboratories for the exclusion of methylati...

Ngày tải lên: 14/08/2014, 21:20

... relationship with. In the case of a doctor-patient relation- ship, the patient is the doctor’s ‘neighbour’ and the doctor must act reasonably to avoid any foreseeable risks that may cause harm to his/her ... It was found by expert evidence that, by not performing further investigations, the two doctors fell short of a professional standard that was reasonably expected of...

Ngày tải lên: 25/10/2012, 10:02

... are highly specifi c for SLE, but not very sensitive. Anti- dsDNA, anti-P and anti-Sm fall into this category in that they are exclusively, or virtually exclusively, found in the sera of persons ... diagnosis. Clearly this is the case for some specifi cities. If a patient is not antinuclear antibody positive, then she (occasionally he) has almost no chance of having SLE. On th...

Ngày tải lên: 12/08/2014, 12:20

... a higher disordance rate. The PR were not aware of this study at the time of perform- ance; all of the PI were involved in the study. Therefore, it is possible that the PI tended to be more attentive ... solely for determining central venous line or endotracheal tube position may only need to be reviewed by the PI for the accuracy of placement. The charges asso- ci...

Ngày tải lên: 12/08/2014, 18:20

... on the standard data collection form (Additional file 1). The indication for the fluid, the specialty and seniority of the fluid prescriber, and the type of fluid prescribed was recorded by the ... research into the clinical effects of hydroxyethyl starches in critically ill patients. Fresenius Kabi has provided an unrestricted research grant to the University of S...

Ngày tải lên: 13/08/2014, 21:21

... for substance abuse in addition to clinical history is necessary for optimal identification of drug use in ED patients [11]. Our findings of low incidence of occult users added to those of other ... consumption between the two groups, but this could very well be explained by the small sample size. The high mean age of the Barcelona Hospital group probably accounts f...

Ngày tải lên: 13/08/2014, 23:20

... radiogra- phy may perform even better, as suggested by Forslind and colleagues [5]. Destructive joint damage judged on conventional radiography occurs within the first years of RA [6] and early detection ... analysis of data. SJ: interpretation of data and draft- ing the manuscript. HST: acquisition and analysis of data. MØ: study design, analysis of data and interpretation o...

Ngày tải lên: 09/08/2014, 07:20

... (between the lower edge of the upper turbinate and the upper edge of the middle turbinate; the lower edge of the middle turbinate and the upper edge of the lower turbinate; the lower edge of the ... because of its ease of use and its ability to obtain data rapidly and non-inva- sively, especially in conscious animals. However, contro- versy remains on its v...

Ngày tải lên: 12/08/2014, 14:20

... an auditory phantom percept related to tonic and burst hyperactivity of the auditory system. Two parallel pathways supply auditory information to the cerebral cortex: the tonotopically organised ... (non-classical) system. The classical pathways use the ventral thalamus, the neurons of which project to the primary auditory cortex whereas the non-classical pathways us...

Ngày tải lên: 08/08/2014, 16:23

... responsible for 1.4% of the total world burden of morbidity and has been proven to increase mortality risk by 50%. Because of the size and sever ity of the problem, early detection is very important. ... associated with early detect ion/recognition of problem-drinkers. On the issue of early diagnosis, AUDIT can offer substantial help since it is quick and easy to...

Ngày tải lên: 08/08/2014, 23:21