Báo cáo y học: "From sequence to structure to networks" pps

... research topics to choose from. This was well reflected at the recent European Conference on Computational Biology in Cagliari. Topics ranged from sequences and structures to systems biology and phylogeny, ... from homologous structures with known function. One of the most widely used ways to detect structural homology is protein structure alignment. This has classically been done by...

Ngày tải lên: 14/08/2014, 21:20

... regulators are required for differentiation, as opposed to the model in which the process is controlled by a small number of ‘master regulators’. A similar strategy could be applied to identify ... an RNA cap to identify TSSs, is the recent discovery that CAGE tags could represent 5' ends of RNAs generated by cleavage and subsequent re-capping [18], and that cytoplasmic enzyme com...

Ngày tải lên: 14/08/2014, 21:20

... biological problems. In bioinformatics and systems biology the topics covered included the prediction of regulatory networks, microarray data analysis, and graph mining for structural biological ... be grouped according to their biological function in a pathway or process, and in many cases modular structure and module components are highly conserved. Ying Xu (University of Georgia, Atlan...

Ngày tải lên: 14/08/2014, 16:21

... ppaatthhwwaayy aannaallyyssiiss PLoS ONE 2007, 22:: e425. 39. Taylor IW, Linding R, Warde-Farley D, Liu Y, Pesquita C, Faria D, Bull S, Pawson T, Morris Q, Wrana JL: DDyynnaammiicc mmoodduullaarriittyy ... 4499:: 624-633. 49. SSNNOOMMEEDD [http://www.ihtsdo.org/snomed-ct] 50. IIHHTTSSDDOO [http://www.ihtsdo.org] 51. HHPPOO [http://www.human-phenotype-ontology.org] 52. Robinson PN, Köhler...

Ngày tải lên: 14/08/2014, 21:20

... merely a common final pathway of inflammation. It seems reasonable to predict that there are both suscep- tibility and regulatory factors, such as fetal polymorphisms of Fc receptors and cytokines, ... by maternal autoantibod- ies. Although the pathways of clearance and cytokine secretion may vary, these scavengers phagocytose both nonopsonized and opsonized apoptotic cells. Concomi- tantly...

Ngày tải lên: 09/08/2014, 01:22

... diagnosed by a rheumatologist at the unit entering the case into the study. All rheumatology units linked to the gen- eral welfare system in the study area participated in the study, as well ... study using only incident cases of new diag- nosed RA, fulfilling the American College of Rheumatology cri- teria, assessed by a specialist in rheumatology. All rheumatology units linked to the .....

Ngày tải lên: 09/08/2014, 07:20

... Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan 2 Department of Orthopaedic Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, 612-8555, Japan 3 Department ... Medicine, Yamaguchi University, Ube, Yamaguchi, 755-8611, Japan 4 Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan Corresponding author: Ya...

Ngày tải lên: 09/08/2014, 14:21

... accuracy to fall off rapidly for CSDeconv. Motif occurrence can be used not only to validate binding sites, but potentially also to find them. It may be possible to avoid blind deconvolution by simply ... previously identified [4,19]. Owing to the ability of CSDeconv to call closely spaced binding sites, it is capable of achieving a greater level of accuracy, as determined by moti...

Ngày tải lên: 09/08/2014, 20:21

... capacity of the extended family to accurately respond to the challenges posed by thepandemictofarmhouseholds.Thisstudyfurthers this observation by showing that foster families appear to not be ... infor- mants were asked to put to gether items generated from the free lists that they thought were similar. They were asked to make as many piles as they liked, but there had to be at...

Ngày tải lên: 10/08/2014, 09:21

... abbreviations AML: acute myeloid leukemia; ET: essential thrombocythemia; MDS: myelodysplastic syndrome; MPN: myeloproliferative neoplasm; PMF: primary myelofibrosis; PV: polycythemia vera. Acknowledgements This ... with acute lymphoblastic leukemia, chronic lymphocytic leu- kem ia, chronic myeloid leukem ia, multiple myelo ma, or thrombocytopenia. The ages of these patients, except for those...

Ngày tải lên: 10/08/2014, 21:23