Báo cáo y học: "Variations in the transcriptome of Alzheimer''''''''s disease reveal molecular networks involved in cardiovascular diseases" potx

Báo cáo y học: "Variations in the transcriptome of Alzheimer''''s disease reveal molecular networks involved in cardiovascular diseases" potx

Báo cáo y học: "Variations in the transcriptome of Alzheimer''''s disease reveal molecular networks involved in cardiovascular diseases" potx

... to the first gene, gene ID 800 refers to the 800th gene. The Y- axis plots the number of links for each gene. The dashed line indi-cates the mean number of links, and the solid line indicates the ... helps in comparing results across studies and obtaining a global overview of the disease pathogenesis. In this paper, we perform a transcriptome- based study by c...
Ngày tải lên : 14/08/2014, 21:20
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Báo cáo y học: "Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling" ppsx

Báo cáo y học: "Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling" ppsx

... effects of diac- erein/rhein on the synthesis of major proteases involved in bone remodelling/resorption, namely MMP-13 and cathepsin K. Moreover, we sought to gain new insight into the effects of the ... μg/mL). Effect of diacerein/rhein on intracellular signalling pathways To gain insight into the mechanisms of these drugs on the OA subchondral bone osteoblasts, we...
Ngày tải lên : 09/08/2014, 10:23
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Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice

Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice

... the gastrointestinal tissues from the cytotoxicity of CY in mice. We also profiled the changes of the expression of growth factors in gastric tissues in response to the damage by CY and protection ... protective effect of AP on CY-induced cytotoxicities in both the hemopoietic and gastrointestinal tissues was undefined. Any of these actions would extend th...
Ngày tải lên : 02/11/2012, 10:19
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Báo cáo y học: "Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study" ppt

Báo cáo y học: "Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study" ppt

... the study was approved by the Ethics Committee of Hôpital Kremlin-Bicêtre (Paris, France). Genotyping All samples were genotyped using the TaqMan allelic dis- crimination assay according to the ... to the rheumatologist in charge of the patient. Each family con- sisted of one RA patient and both parents, with the ethnic- ity as determined by grandparental origin. Charact...
Ngày tải lên : 09/08/2014, 14:20
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Báo cáo y học: "RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro" pps

Báo cáo y học: "RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro" pps

... ALN in vitro. This protective effect of RANKL is likely to be mediated at least in part by an increase in the level of the anti-apoptotic protein Mcl-1. The ability of RANKL, together with other ... alter the level of Bcl-2 in rabbit osteoclasts but caused a marked increase in the level of Mcl-1, an anti-apop- totic member of the Bcl-2 family that is expresse...
Ngày tải lên : 09/08/2014, 14:20
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Báo cáo y học: "Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes." potx

Báo cáo y học: "Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes." potx

... that only one of the two copies of the bystander gene is still in synteny with the corresponding copy of the target gene in the fish genome. The code captures the relationship of the bystander ... regulatory inputs. However, after WGD, breaking off of a part of one GRB may be tolerated as long as the other copy of these disconnected regulatory inputs is sti...
Ngày tải lên : 09/08/2014, 20:20
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Báo cáo y học: "Considerations for the inclusion of 2x mammalian genomes in phylogenetic analyses" ppsx

Báo cáo y học: "Considerations for the inclusion of 2x mammalian genomes in phylogenetic analyses" ppsx

... number of Figure 2. Increase in gene number through evolutionary time for all lineages (blue lines) in the latest Ensembl version (version 59). The red line indicates the lineage leading to the ... basically the same approach (which they call the ‘duplication consistency score’) in EnsemblCompara. We indicated (Figure 7b in Milinko- vitch et al. [2]) that the euther...
Ngày tải lên : 09/08/2014, 22:23
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Báo cáo y học: "Barriers to the implementation of programs for the prevention of mother-to-child transmission of HIV: A cross-sectional survey in rural and urban Uganda" pptx

Báo cáo y học: "Barriers to the implementation of programs for the prevention of mother-to-child transmission of HIV: A cross-sectional survey in rural and urban Uganda" pptx

... mother's decision to test for HIV was the strongest predictor of whether the mother had the intention of testing or not. This finding highlights the importance of the male partner in the ... This may be an inhibitory factor to the willingness to accept VCT. This study reinforces the recommendations made by a study in Tanzania [29] that emphasized the role of...
Ngày tải lên : 10/08/2014, 05:20
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Báo cáo y học: "Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat" ppsx

Báo cáo y học: "Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat" ppsx

... clear clinical need for the development of therapeutic neuromodulatory interventions has been defined as both sympathetic and parasympathetic pelvic innervation is at high risk of injury during surgery ... pelvic cholinergic neurons. We present the first in vivo report of the effects of neurturin upon the recovery of erectile function following bilateral cavernous nerve cr...
Ngày tải lên : 10/08/2014, 09:22
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Báo cáo y học: "Looking through the ''''window of opportunity'''': is there a new paradigm of podiatry care on the horizon in early rheumatoid arthritis" pot

Báo cáo y học: "Looking through the ''''window of opportunity'''': is there a new paradigm of podiatry care on the horizon in early rheumatoid arthritis" pot

... [71] Multidisciplinary guidelines for the management of early rheumatoid arthritis [72] Multidisciplinary team care Podiatry is part of the multidisciplinary team Podiatry is part of the multidisciplinary ... By symptom duration, the definition of early RA has progressively shorted from <5 years to <12- 24 months, whilst very early disease indicates the period...
Ngày tải lên : 10/08/2014, 21:24
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