Báo cáo y học: "Transcriptome content and dynamics at single-nucleotide resolution" pptx

... genomic variation (such as copy-number variations, structural variations or ploidy) on accurate and unbiased tag mapping has yet to be systematically studied. Nevertheless, it is anticipated that improvements ... complexity, and dynamics in these species. A recent study by Bähler and colleagues [1] in the fission yeast Schizosaccharomyces pombe in particular shows how the new RNAseq t...

Ngày tải lên: 14/08/2014, 20:22

... Letter: Language lateralisation and unilateral ECT. Brit J Psychiat 1980, 136:316. 14. Warrington EK, Pratt RT: The significance of laterality effects. J Neurol Neurosurg Psychiatry 1981, 44:193-196. 15. ... Pratt RT: Language laterality in left handers assessed by unilateral ECT. Neuropsychologia 1973, 11:423-428. 21. Geffen G, Traub E, Stierman I: Language laterality assessed by unilatera...

Ngày tải lên: 08/08/2014, 20:23

... IL-23 and p40 and upregulated cell surface HLA-DR, CD40 and CD83. Further, BV fluids decreased MDDC endocytic abil- ity (a marker of stimulation and maturation of DC) and increased proliferation ... BV is associated with increased levels of pro-inflammatory cytokines such as IL-1β and IL-8 [Reviewed in [31]]. IL-1β can induce the production of other pro-inflammatory cytokines, an...

Ngày tải lên: 10/08/2014, 05:20

... neonate. Those infants with IL-13 producing Th2 lym- phocytes may be particularly predisposed to develop asthma [28]. The risk of atopy and asthma is related to failure of the neonate to generate ... early life respiratory illness, family size over time, and the development of asthma and hay fever: a seven year follow up study. Thorax 1999, 54:664-669. 6. Nystad W, Skrondal A, Magnus P:...

Ngày tải lên: 12/08/2014, 18:20

... first described in 1900 by E. Maupas and chosen in the late 1960s by Sydney Brenner as a species for genetic study, the nematode Caenorhabditis elegans has come a long way. The ‘worm’ has made ... Laboratory, Utrecht, The Netherlands) described the construction of a clonal library from 6,000 mutagenized worms that is being directly sequenced for mutations in genes of interest. He estimated...

Ngày tải lên: 14/08/2014, 15:20

... particular enzymatically catalyzed reactions to investigate the possibility that catalysis is mediated by protein dynamics. That is, evolution has crafted the protein backbone of the enzyme to direct ... then that there is a growing body of evidence that protein dynamics could well play a central role in enzymatic catalysis, well beyond standard pictures of loop motions that cause substrat...

Ngày tải lên: 31/03/2014, 23:20

... amplified by 19 cycles of PCR. cDNA was normalized by one cycle of denaturation-reassoci- ation followed by separation of reassociated double-stranded cDNA from normalized single-stranded cDNA by hydroxyla- patite ... synchroneity of late quaternary coccolith datum levels - validation by oxygen isotopes. Geology 1977, 5:400-404. 7. Paasche E: A review of the coccolithophorid Emiliania huxleyi...

Ngày tải lên: 09/08/2014, 20:20

... molecule pathway was the most differentially regulated pathway in all comparisons. The antigen presen- tation and processing pathway was the second most dif- ferentially regulated pathway comparing ... cer- Identification and characterization of PBMo by flow cytome-tryFigure 1 Identification and characterization of PBMo by flow cytometry. A) Peripheral blood was obtained from untreate...

Ngày tải lên: 12/08/2014, 14:20

... Amara A, Liu YJ, Lifson JD, Littman DR, Bhardwaj N: Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic ... eight monkeys were negative for SIV, STLV, and SRV when included in the study, as demonstrated by enzyme- linked immunosorbent assay or PCR analyses. Rhesus macaques were inoculated intrav...

Ngày tải lên: 13/08/2014, 01:20

... containing dextrose and oleic acid and very long chain fatty acids accumulated in cells [52]. Our data showed that a very long chain fatty acyl-CoA synthetase (MGG_08257.5) was up-reg- ulated, suggesting fatty ... rapamycin. Authors' contributions YYO, TM and RAD designed the study; YYO, ND and SC car- ried out the experiments; YYO and HP performed data processing and statist...

Ngày tải lên: 14/08/2014, 08:21