Báo cáo y học: "Transcriptional (dys)regulation and aging in Caenorhabditis elegans" doc

... scored using the remaining nine as training data for determining the cut-off leading to the highest accuracy. The performance was deter- mined by calculating the accuracy value obtained in the ... flanking introns and by increasing the density of silencers in introns relative to the exons they flank. This is ultimately reflected in the higher ERA absolute values obtained. Our analyses...

Ngày tải lên: 14/08/2014, 21:20

... occurrence in complement components C1r/C1s, embryonic sea urchin protein Uegf, and BMP-1 [62]. These domains may be involved in calcium-binding and protein-protein or enzyme–substrate interactions ... (six-cysteine) motif was observed in several hypo- thetical C. elegans proteins [64,65] but was originally described in metridin, a toxin from sea anemone and is also called ShK t...

Ngày tải lên: 23/03/2014, 15:21

... of senescent decline in wild-type individuals is uncertain. Several pathways with longevity phenotypes in knockout animals may not be relevant to normal aging; these include the insulin/IGF-1 pathway, the ... pro-longevity effects of reduced insulin/IGF-I-like signaling and dietary restriction, providing at last a potential link between these longevity pathways and the normal process...

Ngày tải lên: 14/08/2014, 20:22

... subtype B) and V3 CM242 (subtype E) peptides, which distinguishes HIV-1 subtype B and E infection in Thai individuals and confirmed by se- quencing, when indicated [19, 20]. Specimens and ... depression, and did not have central nervous system opportunistic infection, active opportunistic infection in any organ system, pre-existing or known learning disability, or past bra...

Ngày tải lên: 31/10/2012, 15:34

... disturbing airway physiology through a number of different path- ways. Cpn and Mpn species are able to generate proinflammatory cytokines both in vivo and in vitro. 11 Both agents are involved in ... measured by FEV 1 and accordingly associated with a higher daytime symptom score and other markers of asthma severity. 45,48 The timing of the infection may also play an important r...

Ngày tải lên: 08/08/2014, 21:20

... Sitagliptin Intolerant Group 1 Yes Yes Yes n.d. Yes Yes Yes Yes 1 week 38% Positive 30% 2 Yes Yes Yes n.d. Yes Yes Yes Yes 1 week 49% Positive 19% 3 Yes Yes Yes 7 weeks Yes Yes Yes Yes n.d. ... 4 Yes nil nil 8 weeks Yes Yes Yes Yes 1 week n.d. Positive 11% 5 Yes Yes nil 1 week Yes Yes Yes Yes 1 week 33% INS+ICS 0% 6 Yes Yes Yes 2 weeks Yes Yes Yes Yes 1 week 31% n.d. n.d. 7 Yes ......

Ngày tải lên: 08/08/2014, 21:20

... Navy both by adult and by adolescent standards, and to measure levels of hidden alcoholism in the same sample. Problematic drinking is a bi-axial measure involv- ing frequency and quantity of ... information about the amount and frequency of alcohol that is in fact binge drinking. Since the questionnaires used provide indirect information about binge drinking habit in conscript...

Ngày tải lên: 08/08/2014, 21:20

... interaction between proteoglycan and collagen [46]. The composition of cartilage, including proteoglycan content, may be evaluated by observing the intensity of staining. In the present study, ... 4 Tidemark integrity Intact 0 Destroyed 1 Figure 4 Safranin-O/fast green staining of plug cartilage and the shaved area (original magnification 10×)Safranin-O/fast green staining of plug carti...

Ngày tải lên: 09/08/2014, 01:24

Ngày tải lên: 09/08/2014, 10:20

... two IgG(κ) bands and one IgG(λ) band, and a woman with polymy- ositis had both IgG(κ) and IgM(λ) bands. The total number of paraprotein bands was consequently the same in the two study groups (Table ... group in the case– control study is, in part, probably related to the combined use of both a highly sensitive protein stain and highly sensitive immunofixation electrophoresis. U...

Ngày tải lên: 09/08/2014, 10:21