Báo cáo y học: "Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development" potx

... hormone and many of the environmental stress signaling pathways that we have examined. These new findings suggest most aspects of plant physiology are influenced by the circadian system and will help ... genes is Circadian co -regulation of metabolic pathwaysFigure 5 Circadian co -regulation of metabolic pathways. (a) Metabolic pathways for the production of the...

Ngày tải lên: 14/08/2014, 20:22

... cycle'. As indicated several cyclins (cyclin A 1 , cyclin A 2 , cyclin B 1 , cyclin B 2 , cyclin D 1 , cyclin D 2 , and cyclin E 1 ) are downregulated in the ES cell derived cardiomyocytes. Fully differentiated ... oxygen intensively [22], a constant supply of oxygen is indispensable for sustaining cardiac function and viability. This notion is well elucidated by our analysis, i...

Ngày tải lên: 14/08/2014, 20:22

... day 12 of the growth curve, the gene-expression profiles of survivors became relatively con- stant and remained so through day 15. The profiles of days 12- 15 appear most similar to days 1 and ... heterochromatin forma- tion away from centromeres and the mating-type locus [53]. In a separate study, telomeric silencing of a reporter gene and binding of Swi6 at the telomer...

Ngày tải lên: 14/08/2014, 14:21

... a nd 5). Interestingly, the early steps of a dipocyte development in mESCs a re characterized by a dramatic gain of scores of TFs, many Figure 4 Status of the Wnt pathway and effect of exogenous ... the early steps of adipocyte formation involv e important changes in cell signaling, including compo- nents of the Wnt pathway. Of these, we have further investigated the rol...

Ngày tải lên: 09/08/2014, 20:22

... classes of cell motility (N), translation (J) and hypothetical proteins. Interestingly, transcripts encoding proteins of transport and metabolism (P) (such as inorganic ion, amino acids, carbohydrate, ... collection, analysis and interpretation of data and wrote the paper. JS carried out the computational analyses of sRNA. PG provided research support and involved in...

Ngày tải lên: 11/08/2014, 08:20

... determined using SAM [23]. Probes were annotated using the Web-based Affymetrix NetAffx analysis tool [56] and Ingenuity Pathway Analysis (Ingenuity, Moun- tain View, CA). NIA microarray sample and data ... cells/well. Expansion was done by trypsinizing (0.05% trypsin, Cellgro) the cells and replating them every 2 days at a density of 100-200 cells/cm 2 . Cells at population doubl...

Ngày tải lên: 14/08/2014, 08:20

... (3'UTRs) of the messages. Many of the characterized miRNAs are involved in developmental regulation, including the timing and neuronal asymmetry in worm; growth control and apoptosis in fly; brain ... or NRSF) plays a fundamental role in regulating neuronal gene expression and promoting neuronal fate [1,2]. REST contains a zinc-finger DNA-binding domain and two rep...

Ngày tải lên: 14/08/2014, 17:22

... segments defy conventional methods of sequencing and assembly and understandably lag behind the determination of euchromatic segments. They include, for example, Y- chromosome sequences that remain an ... providing valuable insights into the patterns of structural and regulatory genome evolution within and between each of these groups. Eventually, the integration of sequenc...

Ngày tải lên: 14/08/2014, 08:20

... Justice,A.C., Covinsky,K.E ,Berlin,J.A. Assessing the gener- alizability of prognostic information. Ann. Intern. Med. 1999; 130: 515 - 524. 23. Feinstein AR, Walter SD, Horwitz RI. An analysis of Berkson's ... same type of analy- sis, but with the primary care and hospital controls are shown in Tables 6 and 7, respectively. The inter- action [CA 19.9 x AGE] is in Table...

Ngày tải lên: 03/11/2012, 11:34

... within inflamed joints appears to be reg- ulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with FLSs. Once expressed, IP-10 probably plays ... T, Strieter RM: The role of chemokines in inflammatory joint disease. J Leukoc Biol 1996, 58:6-12. 2. Choy EHS, Panayi GS: Cytokine pathways and joint inflamma- tion in rheumatoid arthri...

Ngày tải lên: 09/08/2014, 01:21