Báo cáo y học: "Human genetics branches out in Barcelona" pdf

... abundantly expressed in the unaffected individuals, but not in their affected siblings. The discovery that PLS3 protects against spinal muscular atrophy might help to identify novel targets for therapy. CCooppyy ... for understanding the genetics of complex diseases, where many genes of modest effect may play a role, and pointed out the importance of focusing not only on common varian...

Ngày tải lên: 14/08/2014, 20:22

... ageing Identifying genes controlling human longevity is of increas- ing interest in the light of the general increase in life span in developed countries. In his talk on methods of identifying genes ... isoenzymes CYP2C19 and CYP2D6, for example, are involved in the metabolism of many widely used drugs, and polymorphisms in these enzymes give rise to inter-individual and inter- et...

Ngày tải lên: 14/08/2014, 14:22

... Sequencing was carried out by the dideoxy- nucleotide chain termination method on an ABI Prism 377 automatic sequencer ( Applied Biosystems), using the ABI PRISM Dye Terminator cycle sequencing ... detection; in fact in the former study 87 liver specimens, obtained mainly in occasion of liver transplantation for various causes, were analyzed by four PCRs. The presence of PARV4 DNA in...

Ngày tải lên: 12/08/2014, 01:22

... analysis. BE was involved in study design and data collection. UM was involved in data management, statistical analysis and data interpretation. RS was involved in study design, data analysis, ... data analysis and interpretation, and writing of the manuscript. DF, MS and FW were involved in data analysis and interpretation, and writing of the manuscript. WK was involved in study de...

Ngày tải lên: 13/08/2014, 21:21

... developed training modules, and more students are coming out of this training programme regularly. The ISCCM has also been very active in interacting with various medical councils in India. As a ... who-is-who in critical care in India, but also many international stalwarts over the past 8 years. Good quality original work has now started emerging, and is being accepted for publicat...

Ngày tải lên: 12/08/2014, 19:21

... their own expression. Fly proteins are indicated in grey and mouse proteins in orange; proteins indicated in black are found in both. The regulators are bZIP type factors in fly and nuclear hormone ... reinhardtii clock using a newly developed collection of insertion mutants and analyzing insertion lines containing the reporter [14]. Such an approach has been very successful in A....

Ngày tải lên: 14/08/2014, 16:21

... oocysts for only 2 to 3 weeks following primary infection. Mature cats are less likely to shed Toxoplasma if they have been previously infected. Litter box hygiene is the main precaution in ... pass oocysts in their feces. They become infected by eating infected rodents, birds, or other small animals. Once oocysts are shed, they re- quire 1 to 5 days to sporulate and become infective...

Ngày tải lên: 03/11/2012, 11:06

... carbohydrate chains by appropriate glyco- syltransf erase s. Changes in the activities of NSTs may affect the structure of oligosaccharide chains by affecting the availability of substrates for glycosyltransferases ... Biochemistry, University of Ken- tucky Medical Center, College of Medicine, Lexington, KY, USA. Present address: Department of Applied Chemistry, Kogakuin University, Nishi-...

Ngày tải lên: 21/02/2014, 15:20

... approach to obtain novel IgA binding ligands, using combinatorial protein engineering to change the binding specificity of an already existing receptin protein. Employing a 58-amino- acid domain derived ... biosensor binding studies. To investigate if the IgA binding capability of the Z IgA1 affibody could possibly be explained by any IgA binding activity present already in the Z domain scaff...

Ngày tải lên: 08/03/2014, 23:20

... fat-soluble vitamin esters and cholesterol esters in the small intestine. In some species, including humans, the gene is also expressed in the lactating mammary gland and the resulting protein is a constituent of ... completely dispensable for the typical functional properties of BSSL, i.e. catalytic activity, bile-salt activation, heparin binding, heat stability, stability at low pH an...

Ngày tải lên: 24/03/2014, 03:21