Báo cáo y học: "Biodefense versus bioterrorism" doc

... front-page story by Nicholas Wade in the 21 August edition of the New York Times [http://www. nytimes.com/2008/08/21/science/21anthrax.html?partner= rssnyt&emc=rss]. I’m drawing heavily on this ... case was finally solved after almost seven years have come to light, and what they reveal is the critical role of genomics in identifying the source of the anthrax. In fact, many of the techniq...

Ngày tải lên: 14/08/2014, 20:22

... function or changes in the type 1–type 2 cytokine balance. 8,9 Chronic stress has recently been shown to increase susceptibility to skin cancer by suppressing type 1 cytokines and protective T ... cell-mediated immunity. Int Immunol 2005;17:1059–69. 58. Blecha F, Barry RA, Kelley KW. Stress-induced alterations in delayed-type hypersensitivity to SRBC and contact sensitivity to DNFB in mice. ....

Ngày tải lên: 08/08/2014, 21:20

... body plethysmography, as a physiologically meaningful, noninvasive parameter of bronchoconstriction for mice and rats [13-17]. No report has as yet directly investigated the ability and utility ... assessed with a glass-made head-out body plethysmograph system for four mice as previously described [14,17,19]. Briefly, mice were placed in the body plethysmographs while the head of each animal...

Ngày tải lên: 12/08/2014, 18:20

... and β 2 receptors, thereby counteracting arterial hypotension by increasing systemic vas- cular resistance and possibly myocardial inotropy [6]. On the other hand, phenylephrine could be preferable ... citation purposes) Phenylephrine increases systemic vascular resistance by selectively stimulating α 1 adrenoceptors without a compensa- tory increase in myocardial contractility, and thus i...

Ngày tải lên: 13/08/2014, 11:23

... controversial, however, and is hampered by many small retrospective studies with potential selection bias; most evidence is also confounded by relatively recent changes in practice such as leucodepletion ... received marginally more RBCs. Cardiac surgery studies  e largest studies in this fi eld have been performed in cardiac surgery. Van der Watering and colleagues retro- spectively rev...

Ngày tải lên: 13/08/2014, 20:21

... NR W121G 1.1 6 NR W121F 1.5 31 0.05 W12 1Y 1.3 22 0.03 Y1 22Q 2.2 333 0.4 Y1 22F 1.2 660 4.6 W121Q /Y1 22Q 1.7 9 NR W12 1Y/ Y122W 1.2 7 0.13 W121F /Y1 22F 1.5 7 NR Y2 26F 1.3 626 2.4 2982 V. Drosou et al.(Eur. ... i.e. its (already low) residual electron transfer activity is not maintained by the neighbouring tyrosine, while the W121F /Y1 22F mutant activity may be viewed as a commitment...

Ngày tải lên: 22/02/2014, 07:20

... except ipsilateral axillary lymph nodes (T2-3, N0-1, M0), were eligible for the study provided that they had not pre- viously received any type of systemic or local primary treatment for breast ... ran- domly allocated to receive four 3-weekly cycles of preoperative XT (capecitabine 1000 mg/m 2 BID on days 1-14 and docetaxel 75 mg/m 2 on day 1) or AC (doxorubicin 60 mg/m 2 and cyclop...

Ngày tải lên: 08/08/2014, 17:20

... etanercept as monotherapy with only partially satisfactory responses, the addition of MTX might give additional clinical benefit. While many of these implica- tions can and probably will be tested through ... years of disease activity, rheumatoid factor positivity and shared epitope positivity. However, a somewhat higher proportion of patients were female in the group receiving combination th...

Ngày tải lên: 09/08/2014, 01:23

... and phosphorylation of receptor cytoplasmic domain tyrosine residues. STATs dock on these phosphotyrosine motifs by means of their Src homology 2 (SH2) domains. STATs are then phosphorylated on ... dephosphorylated in the cytoplasm, possibly by SHP-2 [60]. It seems that there is substrate specificity in the dephosphorylation of STATs by PTPs, and it is not clear how this specificity is achiev...

Ngày tải lên: 09/08/2014, 01:23

... people on my staff.” Sadly, for the United States and for the world, he was not being ironic - he actually believed what he said. The notion that people close to the king typically try to remain ... http://genomebiology.com/2009/10/11/113 Petsko: Genome Biology 2009, 10:113 Former US President George W Bush was not a man given to irony. Yet, asked where he got his information, he replied,...

Ngày tải lên: 09/08/2014, 20:20