Báo cáo y học: "Plastic architecture of bacterial genome revealed by comparative genomics of Photorhabdus variants" ppsx
... genome architecture Do large genomic rearrangements occur randomly or are they shaped by drastic selective evolutionary forces? Several years of comparative genomics between whole bacterial genomes showed ... secondary forms. We identify substantial plasticity of the genome architecture of some variants, mediated mainly by deletions in the 'flexible' gene poo...
Ngày tải lên: 14/08/2014, 20:22
... inflammatory response. Highest levels of expression are indicated by progressively brighter shades of red and lower expression levels represented by progressively brighter shades of green, as shown by ... category will be a major goal of our future studies. How full a survey of the wound healing process is revealed by our microarray study? The Affymetrix GeneChip we used...
Ngày tải lên: 14/08/2014, 14:21
... inspiratory- expiratory sequence manifest as a large burst of inspira- tory EMG activity immediately followed by a burst of expiratory ABD activity with an inspiratory-expiratory waveform of intrathoracic ... Ethics committee of Jessenius Faculty of Medicine Commenius University and the State veterinary administration of Slovakia (N° 5492/1999-500 and 6708/03-220) or by the Un...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: " Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia" ppt
... therapy may correct low TGN levels and thereby improve the prognosis of these patients. This is currently being explored in the NOPHO cooperation. 4. Dose adjustments by genetics better than by toxicity ... tradi- tional dose adjustments by toxicity or drug measurements. 5. Reducing toxicity or increasing efficacy must not be upset by less efficacy or more toxicity The improved cure...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: " Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases" docx
... mod- ified by many DNA methyltransferases from different RM systems [16,17]. This activity was first recognized for restric- tion of incoming bacteriophage genomes carrying hydroxymethylcytosine ... resistance of hydroxylmethy-C- containing phage to restriction enzymes but its sensitivity to McrBC [79] and the resistance of glucosylated hydroxyme- thyl-C to GmrSD but its inhibition b...
Ngày tải lên: 14/08/2014, 21:20
Báo cáo y học: " Premature terminator analysis sheds light on a hidden world of bacterial transcriptional attenuation" pptx
... 3:e126. 22. Vitreschak AG, Lyubetskaya EV, Shirshin MA, Gelfand MS, Lyubetsky VA: Attenuation regulation of amino acid biosynthetic operons in proteobacteria: comparative genomics analysis. FEMS Microbiol ... recently detected by deep sequencing [46]. Sequence logos were produced using Weblogo [81]. Naville and Gautheret Genome Biology 2010, 11:R97 http://genomebiology.com/2010/11/9...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: "hytol-based novel adjuvants in vaccine formulation: 2. assessment of efficacy in the induction of protective immune responses to lethal bacterial infections in mice" ppsx
... administered intraperitoneally at 10-day intervals. The efficacy of the phytol and PHIS-01, as compared to IFA, was assessed by ELISA in terms of anti -bacterial antibody and inflammatory cytokines. We also examined ... K, Fukada M, Kawai M, Yokochi T: Detection of lipopol- ysccharide (LPS) and identification of its serotype by an enzyme-linked immunosorbent assay (ELISA) using p...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: "Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages" pot
... of adenylyl cyclase by the Gα s subunit [19,29]. It is known that the Gα s subunit undergoes significant conformational changes upon exchange of GDP by GTP, affecting its affinity for adenylyl ... role of the pre-existing equilibrium of conformational sub-states in allostery pro- posed already over 20 years ago [6] is increasingly receiving attention, emphasizing the key role o...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: "Functional architecture of Escherichia coli: new insights provided by a natural decomposition approach" ppt
... nucleotide, and cofactor biosynthesis Motility http://genomebiology.com/2008/9/10/R154 Genome Biology 2008, Volume 9, Issue 10, Article R154 Freyre-González et al. R154.9 Genome Biology 2008, 9:R154 node ... genes. An analysis of the biological function of the isolated genes showed that many of them are elements of the basal machinery of the cell (tRNAs and its charging enzymes,...
Ngày tải lên: 14/08/2014, 21:20
Báo cáo y học: "Bench-to-bedside review: The MET syndrome – the challenges of researching and adopting medical emergency teams"
... data [52-56]. Inherent within this type of evidence is the lack of rigour and generalisability. Furthermore, the magnitude of the effect of the MET may be influenced by institution-specific administrative ... 4 of 6 (page number not for citation purposes) Figure 1 The effect of delay in medical emergency team (MET) calls on mortality in two cohorts of patients at the start of...
Ngày tải lên: 25/10/2012, 10:35