Báo cáo y học: " Protein structure protection commits gene e

Báo cáo y học: " Protein structure protection commits gene expression patterns" pps

... COR1 YBL045C Blue Peptidase_M16 QCR2 YPR191W Green Cytochrom_B_C COB Q0105 White Cytochrom_C1 CYT1 YOR065W Purple UCR_TM RIP1 YEL024W Orange UCR_14kD QCR7 YDR529C Cyan UcrQ QCR8 YJL166W Yellow ... that the protection of a functionally competent protein structure in yeast drives co -expression of its binding partners to an extent that is determined by the structure vulnerability. In s...

Ngày tải lên : 14/08/2014, 20:22

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Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot

... might directly regulate the sensitivity of iNOS to calpain [6]. PIN1 may also regulate expression of inflammatory proteins by an effect on calpain. Cyclooxygenase (COX)-2 is induced by LPS, IFN, ... lipopolysaccha- ride stimulates cyclooxygenase-2 expression and prostaglan- din I(2) and E(2) production in human coronary artery endothelial cells. J Immunol 2007, 179:7899-7906. 8. Kang...

Ngày tải lên : 11/08/2014, 08:22

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Báo cáo y học: " Protein function annotation by homology-based inference" pps

... 3D structures of as many proteins as possible from one species. Genome BBiioollooggyy 2009, 1100:: 207 Review PPrrootteeiinn ffuunnccttiioonn aannnnoottaattiioonn bbyy hhoommoollooggyy bbaasseedd ... 3D structure is available, domain interactions can be inferred: by identifying domain pairs that are significantly overrepresented in interacting proteins [72]; by coevolutionary analysis...

Ngày tải lên : 14/08/2014, 21:20

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Báo cáo y học: "Transporter Molecules influence the Gene Expression in HeLa Cells"

... employed the Fmoc (9-fluorenyl-methyloxycarbonyl) methodology [37, 38] in a fully automated multiple synthesizer (Syro II from Multi Syntech Germany). As coupling agent 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylu- roniumhexafluoro-phosphate ... impact on the gene expression patterns, when analyzing the efficacy and the genetic consequences of targeted gene therapy in vitro (and...

Ngày tải lên : 03/11/2012, 11:44

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Báo cáo y học: "Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies" doc

... technology is currently highly efficient for genome-wide array analysis, new surfaces provided in the context of spotting technology might improve sensitivity [32]. Gene expression profiles of only ... each gene in physiology and pathology. High-throughput technologies for gene expression profiling provide the first practical basis for applying this information. In rheumatology, wit...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Characterization of histopathology and gene-expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specime" pot

... study, we analyzed gene- expression profiles in the synovial lining tissues in situ in early RA using synovial specimens obtained by targeted biopsy, followed by LCM and cDNA microarray analyses. ... in early RA. That is, we prepared synovial specimens from early RA by targeted biopsy under arthros- copy, and analyzed gene- expression profiles in the synovial lining tissues selected...

Ngày tải lên : 09/08/2014, 06:23

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Báo cáo y học: "An atlas of bovine gene expression reveals novel distinctive tissue characteristics and evidence for improving genome annotation" pot

... relatively intact pseudogenes or duplicated genes were left out of the analysis . An illustrative example is provided by GAPDH [GeneID:281181], the gene encod- ing the constitutively expressed glyceraldehyde-3-phosphate ... substantially dif- ferent from these two tissues in cluster F1. The analysis of fatty tissues also illustrates a limitation of the ontol- ogy system, as clearly the fa...

Ngày tải lên : 09/08/2014, 22:23

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Báo cáo y học: "A dynamic model of gene expression in monocytes reveals differences in immediate/early response genes between adult and neonatal cells" potx

... Holocarboxylase synthetase (biotin-[proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) 47 D00943 MYH6 Myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic ... recom- mended by the manufacturer. Analysis by flow cytometry was accomplished on a FACS Calibur automated bench- top flow cytometer. Data obtained by flow cytometry was analyzed by non-parametric ....

Ngày tải lên : 11/08/2014, 08:21

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Báo cáo y học: " Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A" potx

... This protein contains the apparently unique amino acid hypusine that is formed by the post-translational modification of a lysine residue catalyzed by deoxyhypusine synthase and deoxyhypusine hydroxylase ... eIF5A lysine-50, yielding deoxyhypusine (Dhp); and its subsequent hydroxylation, catalyzed by DOHH, yielding hypusine (Hpu). DHS is inhibited by GC7 and DOHH by CPX and DEF, as indica...

Ngày tải lên : 12/08/2014, 23:22

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Báo cáo y học: "Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep" pdf

... RNA isolated from lymphoma-derived cell lines (CL267), 24 h-cultured blood-derived lymphocytes (BL267-24 h), fresh lymphoma (L267) and freshly isolated blood-derived lymphocytes (BL267). EnvA/Tax2 ... cytotoxicity and cancer. Semin Cancer Biol 2006, 16:124-136. 27. Taniguchi Y, Nosaka K, Yasunaga J, Maeda M, Mueller N, Okayama A, Matsuoka M: Silencing of human T-cell leukemia virus type I...

Ngày tải lên : 13/08/2014, 05:22

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