Báo cáo y học: "Evolution of protein complexes by duplication of homomeric interactions" ppt
Báo cáo y học: "Evolution of protein complexes by duplication of homomeric interactions" ppt
... photosystem (Type-I RC), the Duplication of subunits in protein complexesFigure 4 Duplication of subunits in protein complexes. (a) Nearly 40% of the protein complexes have homologous subunits (gray bars). ... only two dif- ferent interfaces are formed (α:β and β:α; Figure 5b, left). Evolutionary cores of protein complexes and asymmetry Our hypothesis is that many p...
Ngày tải lên: 14/08/2014, 20:22
Tài liệu Báo cáo Y học: Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants pdf
... of isocitrate into succinate and glyoxylate. The reactions catalyzed by ICL and malate synthase (MS) do not occur in the tricarboxylic acid cycle. They are usually catalyzed by s eparate enzymes in ... fungi. Malate synthase (MS) Glyoxylate H 2 O acetyl-CoA ! malate CoASH MS (EC 4.1.3.2) catalyzes the transfer of the acetyl moeity of acetyl-CoA to glyoxylate to yield L -malate...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo khoa học: Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase pptx
... dopamine; L -DOPA, L -3,4-dihydroxyphenylalanine; PAH, phenylalanine hydroxylase; TH, tyrosine hydroxylase. Enzymes:aromatic L -amino acid decarboxylase (EC 4.1.1.28); phenylalanine hydroxylase (phenylalanine-4-hydroxylase; EC ... attraction of the tyrosine ammonium moiety by the negatively charged Asp425 (distance 3.4 A ˚ ) and the formation of an H-bond counteract the repulsion of t...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo Y học: LRP130, a protein containing nine pentatricopeptide repeat motifs, interacts with a single-stranded cytosine-rich sequence of mouse hypervariable minisatellite Pc-1 docx
... the same protein produced by processing of mLRP130. Subcellular localization of mLRP130 was analyzed by immunofluorescence microscopy and cell fractionation analysis. The localization of mLRP130 ... aliquot of eluate was used for electrophoretic mobility shift assay. Electrophoretic mobility shift assay (EMSA) DNA-binding activities of mLRP130 were analyzed by EMSA as describ...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "γ A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis" ppsx
... regulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with fibroblast-like synoviocytes, and that IP-10 may contribute to the recruitment of specific ... reg- ulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with FLSs. Once expressed, IP-10 probably plays a crucial role in t...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes" pps
... inhibition of AP-1 complex synthesis, normally induced by BCP crystals. Conclusion In summary, this study showed that OCP crystals, a member of the family of BCP crystals, caused inflammation by directly activating ... methyl ester (L-NAME), cycloheximide, actinomycin D, pepstatin, aprotinin, leupeptin, phenylmethyl sulfofluoride, poly-(2- hydroxyethyl methacrylate; poly-HEMA) and b...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Glucosamine affects intracellular signalling through inhibition of mitogen-activated protein kinase phosphorylation in human chondrocytes" pps
... nuclear factor-κB subunit, namely p65 (data not shown). The decreased phosphorylation MAPKs may be explained by the role played by glucosamine in O-glycosylation of some proteins. Glucosamine, when ... that O-glycosylation on JNK and p38 MAPKs inhibits their phosphorylation by utilizing the same sites, either by steric hindrance or modulation of the local pro- tein structure. O-gl...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells" pdf
... Surface antigens of normal THP-1 cells were examined by flow cytometry. (b) To analyze the effect of IFIT4 on phenotypic changes of dendritic cell-like cells (DCLCs) during the process of dif- ferentiation, ... antigens of CD40, CD80, CD86, CD83, HLA-DR, CD14 and CD1a on the surface of those DCLCs were analyzed by flow cytometry. Appropriate fluorochrome or isotype control...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Evolution of temporal order in living organisms" pot
... this study the growth rates of various strains of cyanobacteria having dif- Competition between rhythmic and arrhythmic strains of cyanobacteriaFigure 7 Competition between rhythmic and arrhythmic ... a tool primarily adaptive to daily cycles of the natural envi- ronment. Initially several geophysical cycles may have played crucial roles in exerting selection pressure, while later, da...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Evolution of Wenger''''s concept of community of practice" ppt
... 5 Department of Health Policy, Management and Evaluation Faculty of Medicine, University of Toronto, Toronto, Canada and 6 Canadian Institutes of Health Research; School of Nursing, University of Ottawa, ... 'Community' generally describes groups of people (e.g., a town, a school) connected by a common interest and who define their identities by the roles they p...
Ngày tải lên: 11/08/2014, 05:21