Báo cáo sinh học: "Combined therapy with cyclophosphamide and DNA preparation inhibits the tumor growth in mice" docx

... purposes) Genetic Vaccines and Therapy Open Access Research Combined therapy with cyclophosphamide and DNA preparation inhibits the tumor growth in mice Ekaterina A Alyamkina 1 , Evgenia V Dolgova 1 , ... injection, and they received 0.5 mg DNA during the interval between the two CP injections (30–40 min after the first CP dose). The control groups in e...

Ngày tải lên: 14/08/2014, 19:22

... gene therapy in combination with immuno-gene therapy is attractive for many malignancies. The present study could be concluded that the combination therapy of HRP/IAAandIL-12wereabletoreducethetumor growth ... assessing both tumoral histology and infiltration of T-lymphocytes, and evaluating toxic studies. The data showed that combination gene therapy increased the t...

Ngày tải lên: 18/06/2014, 19:20

... represents the data obtained with vemurafenib treatment, the blue line with metformin, and the red line with combination treatment. b) Combination index for the combination of 5 μM vemurafenib and 10 ... [9,10]. Conversely, the effects on pACC were mainly derived from single agent metformin, where in most cell lines the increases in pACC were noted concordantly with...

Ngày tải lên: 18/06/2014, 19:20

... Biology 2003, 2:4 reflection illumination to observe the turnover of ATP by myosin as the myosin interacted with a single actin filament. Binding, hydrolysis and release of a fluorescently labeled nucleotide ... of the trap- ping laser beam relative to the fluorescence of the probe. Another nice feature of their experiment [8] is the large increase in the rhodamine probe f...

Ngày tải lên: 06/08/2014, 18:20

... been reported, including 5-fluorouracil, doxorubicin, and mitomycin (FAM) [4], epirubicin and cisplatin (CDDP) in combination with continuous infusion of 5-fluorouracil (ECF) [5], and 5-fluorouracil and ... promising activity in gastric can- cer, both as monotherapy [9] and in combination with other agents [10-12]. We performed phase I and phase II studies of combination...

Ngày tải lên: 09/08/2014, 03:21

... to the same portion. WB performed the statistical analysis. MN participated in the statistical analysis and in the drafting of the manuscript. CB contributed to interpretation of the data and ... the 2-, 4- and 8-fold tumour regrowth after single and combined treatment with a 10 Gy top up dose, exemplarily. In this subset of experi- ments, five of nine mice were...

Ngày tải lên: 09/08/2014, 10:20

... sub-clinical infection that increases the proliferation of certain immune cell types and/ or the production of acute phase proteins, with a reduction in growth being a consequence of infection. The ... performing animals using either of these measure- ments, we need to fully understand the underlying mech- anisms that control the relationship between these traits and weight...

Ngày tải lên: 14/08/2014, 13:21

... to change the sign in the first term on the right hand sides in (15), (18) and (19), while (20) remains unchanged. 3.3 Reduction of a certain singular integral operator The results of the previous ... construction of a reducing operator, which will be useful in the study of the integral system of the first kind arising in the Dirichlet problem. Section 4 is devoted t...

Ngày tải lên: 18/06/2014, 22:20

Ngày tải lên: 05/08/2014, 10:20

... associated with intensive DNA synthesis do not contain it. Moreover, the gene of the major uracil-eliminating UNG is missing, possibly leading to sustained presence of uracil in DNA. Tissues containing ... basal and HGF induced cell motility. HGF stimulation induced a significant increase in integrin alpha6 and decrease in integrin alpha v and beta4 expression levels. In...

Ngày tải lên: 19/02/2014, 07:20