Báo cáo y học: "Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database" ppsx
Báo cáo y học: "Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database" ppsx
... improve the ability of BLAST to search for structural homology of a query sequence to a known protein structure or a family of proteins. This tool searches for the structural alphabet high-scoring ... basis, and effective and reliable search capabilities) and employs a kappa- alpha (κ, α) plot derived structural alphabet and a new substitution matrix...
Ngày tải lên: 14/08/2014, 18:20
Báo cáo y học: " Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients " ppsx
... The study monitor of the LCC includes the patient in CAP- NETZ by applying the following criteria: age ³ 18 years, a pulmonary infiltrate diagnosed by chest x-ray, clinical symptoms consisting of ... study. The study was approved by the local eth- ical committee. Our study was not an intervention study with implementation of standardized criteria for the diag- nosis and therapy of...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model" ppsx
... fying the phosphorylation of protei ns of the cytoskeleton [44]. As well as decreasing pro-inflammatory cytotrafficking (cytokines and NO synthesis) [10], acidification and phosphorylation and, in consequence, ... analog scale, and electrodermal activity (EDA). At necropsy (Week 8), macroscopic and histomorphological analyses of synovium, cartilage and subchondral bone of t...
Ngày tải lên: 12/08/2014, 17:21
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... 2002 Cytochrome c structure and stability (Eur. J. Biochem. 269) 3361 and structure analyses of bacterial cytochromes c, including HT c-552 and PA c-551. MUTAGENESIS STUDIES FOR STABILITY In general, ... Yamazaki, K., Kyogoku, Y. & Kobayashi, Y. (1998) Solution structure of thermostable cyto- chrome c-552 from Hydrogenobacter thermophilus determined by 1 H-NMR spectros...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps
... L. Juliano Structural Bioinformatics Core Facility, University of North Carolina, Chapel Hill, NC 27599, USA 3 Division of Rheumatology, University of Pennsylvania School of Medicine and Philadelphia ... extremely disordered proteins: implications for the etiology of systemic autoimmunity Philip L Carl 1 , Brenda RS Temple 2 and Philip L Cohen 3 1 Department of Pharmacol...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... inducing anti-inflammatory cytokines or neutralizing pro-inflammatory cytokines should be critically evaluated before considering this form of therapy. Depletion of neutrophils significantly reduced the severity of CAIA ... multicellular inflammatory process, including infiltration of lymphocytes and granulocytes into the articular cartilage, proliferation of synovial fibroblasts...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects" pot
... of Groups A and B at study days 14 and 28, for Group C subjects at study days 28 and 42, and for Group D subjects at study days 70 and 84. Healthy male or female subjects (aged 18–65 years inclusive) with ... serotypes, and approximately 25% of subjects responded to at least six different serotypes by day 14 (Figure 5a) and by day 28 (Figure 5b). Table 3 Geometric means...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx
... (HMFN0839)* 1-Acylglycerol-3-phosphate O-acyltransferase 9 [GenBank:NM_032717.3 ] 34 MTHFD2 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [GenBank:NM_006636.3 ] 35 ... Diseases (NIAID), Cooperative Center for Translational Research on Human Immunology and Biodefense, Baylor Institute for Immunology Research and Baylor Research I...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " b-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryo" docx
... morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos Yi-Ting Wu 1 , Che Yi Lin 1 , Ming-Yuan Tsai 2 , Yi-Hua Chen 3 , Yu-Fen Lu 3 , ... induction of apoptosis of endocardium and erythrocytes. In addition, this study further demonstrates the importance of endocardium and hemodynamic forces on heart morphogenesis a...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Computerized tomography myelography with coronal and oblique coronal view for diagnosis of nerve root avulsion in brachial plexus injury" potx
... tomography myelography visual-izing only a part of the rootletsFigure 3 Axial view of computerized tomography myelography visual- izing only a part of the rootlets. Publish with BioMed Central and ... visualization of the rootlets and orientation of the exact level of the root. Sensitivity and specificity for coronal and oblique coronal views of unrecognition of intr...
Ngày tải lên: 10/08/2014, 10:20