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Báo cáo y học: "Base relative quantification framework and software for management and automated analysis of real-time quantitative PCR data" potx

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Báo cáo y học: "Base relative quantification framework and software for management and automated analysis of real-time quantitative PCR data" potx

... quantification framework and software for management and automated analysis of real-time quantitative PCR dataJan Hellemans, Geert Mortier, Anne De Paepe, Frank Speleman and Jo VandesompeleAddress: ... properly cited. Automated analysis of real-time qPCR data<p>qBase, a free program for the management and automated analysis of qPCR data, is described</p>AbstractAlthough quantitative ... free program for the management and automated analysis of qPCR data.BackgroundSince its introduction more than 10 years ago [1], quantitative PCR (qPCR) has become the standard method for quantifica-tion...
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Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"

... theintegrity of the data and the accuracy of the data analysis. MK contributed tostudy concept and design, to analysis and interpretation of data and to draft-ing of the manuscript and critical ... design, analysis of results, interpretation of findings, and drafting of the paper.Independent statistical analysis. The accuracy of the data analysis was inde-pendently verified by William ... pooled analysis included only the subset with VAP. Adults were eligible for study 2 if they had VAP as previously defined. Studyprotocols and informed consent forms were reviewed and approved by...
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Báo cáo y học: "Candida albicans genome sequence: a platform for genomics in the absence of genetics" potx

... theabsence of genetic screens. We in the C. albicans researchcommunity are very grateful to the Stanford DNA Sequenc-ing and Technology Center for their efforts. References1. Sequencing of Candida ... future.The assembly of a complete diploid genome sequence for SC5314 has allowed a reliable estimate of the frequency of heterozygosities in C. albicans of 4.21 polymorphisms perkb, or 1 polymorphism ... Department of Dermatology, ColumbiaCollege of Physicians and Surgeons (New York, USA). Theoriginal isolate number was 1775 and the strain is identicalwith strain NYOH#4657 in the New York State...
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Báo cáo y học: "The NFI-Regulome Database: A tool for annotation and analysis of control regions of genes regulated by Nuclear Factor I transcription factors" pdf

... consistent [23]. This functionality is currentlyprovided by the software layer of the NFI-Regulome data-base and by taking advantage of the featu res provided bythe underlying database we define t ... annotation, and the ability to extract and u seinformation stored in genome databases, is an essentialpart of genomic and bioinformatic analysis [1-4]. Whilenow primarily a basic research tool, analysis ... createmodified displays of the sites or for the calculation of relative locations and distributions of binding sites using other software. Gronostajski et al. Journal of Clinical Bioinformatics 2011,...
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Báo cáo y học: " Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma" pps

... American Cancer Society: Cancer Facts and Figures. 2009.2. Chen Y, Chen C: DNA copy number variation and loss of heterozygosityin relation to recurrence of and survival from head and neck squamouscell ... make comparisons of expression levels and transformed to select genes for further analysis. LOH/AI signals are analyzed to identifyregions (and hence regional genes) for both tumor and normal tissue ... genome-wide scans of HNSCC tumors to generatea list of candidate genes. This list is then used to search for likely HNSCC-relevant signaling pathways in thepathway analysis framework (based...
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Báo cáo y học: "Dual equipoise shared decision making: definitions for decision and behaviour support interventions" docx

... whosupport mandatory autonomy [33].A good example of this kind of situation and one that cli-nicians face daily is supporting a patient managing along-term condition. For the majority of these ... Falck-Ytter Y, Alonso-CoelloP, Schünemann HJ, for the GRADE Working Group: Rating quality of evidence and strength of recommendations GRADE: anemerging consensus on rating quality of evidence and strength ... Decision aids and breastcancer: do they influence choice for surgery and knowledge of treatment options? Journal of Clinical Oncology 2007,25:1067-1073.26. Fisher B, Anderson S, Bryant J, Margolese...
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Báo cáo y học: "How HTLV-1 may subvert miRNAs for persistence and transformation" pot

... number of miRNAs havinglinks with cancer and being overexpressed in regulatory Tlymphocytes. Their rationale for miRNA selection wasthat the phenotype of Tregs resembles that of ATL cells.RT -PCR ... examples of subversion of cellular miRNAby viruses, the field of viral oncogenesis mediated throughmiRNA-expression remains insufficiently explored. Thepapers by Pichler et al. [30] and by Yeung ... level of complexity by identifying miRNAs asbeing either directly activated by Tax or associated withHTLV-1 induced cell transformation.The approaches used to narrow down the spectrum of candidate...
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Báo cáo y học: "Single food focus dietary guidance: lessons learned from an economic analysis of egg consumption" docx

... necessarilywide and still contain uncertainty. Future studies couldreplicate the format of this analysis, eventually narrowingthe estimates. In the absence of such studies, this analysis represents ... consumption and coronary heartdisease and found that very few had adjusted for otherdietary intake (particularly total calories, fiber, and fat) and advise caution in interpreting these types of studies.Finally, ... inpatient, and prescription medications for cataract. They estimatedthat the cost was $6957 for patients age 40 to 64 years and $6191 for adults 65 and older. The average of these twocosts was used for...
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Báo cáo y học: " Integrating mental health into primary care for displaced populations: the experience of Mindanao, Philippines" doc

... counseling and cognitive behavioraltechniques for the management of anxiety and depressivesymptoms. This choice of psychotherapeutic interven-tions was based on the existing evidence of its effective-ness ... theMinistry of Health via a memorandum of understanding,which is the usual procedure for NGOs operating inthese contexts. No supplementary interventions wereconducted for the analysis presented ... primarylevel. They provided psychological first aid, brief psychotherapy and referral for severe patients. Patientcharacteristics and outcomes in terms of Self-Reporting Questionnaire (SRQ20) and...
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Báo cáo y học: "Figuring out what works: a need for more and better studies on the relationship between ICU organization and outcomes" potx

... surgery, and emergency medicine. While not perfect, their analysis is appropriate, adjusting for the type and severity of illness and a number of other potentially confounding variables and ... quality improvement, every aspect of what we do and how we do it is a candidate for study and change. While we need much more rigorous research assessing every aspect of this large question, ... the intrinsically clustered data.  ey found some diff erences according to intensivist specialty, most prominent of which was that adjusted ICU mortality was signifi cantly lower for patients...
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