Báo cáo y học: "Reduced efficacy of selection in regions of the Drosophila genome that lack crossing over" doc

... <it> ;Drosophila yakuba </it>are consistent with a severe reduction in the efficacy of selection in the absence of crossing over, resulting in the accumulation of deleterious mutations in these ... efficacy of selection in the absence of crossing over, resulting in the accumulation of deleterious mutations in these regions. Our resu...

Ngày tải lên: 14/08/2014, 17:22

... circulating B lymphocytes expressing for most of them the CD5 and CD11b cluster of differentiation markers and, interestingly, this phenomenon occurred independently of the type of mutant. Increase of ... pathogenesis and infectivity in vivo. Interestingly, B cell lymphocytosis occurred in all sheep independently of the type of provi- rus (Figure 1B, compare absolute n...

Ngày tải lên: 13/08/2014, 13:20

... pain [7]. Glucosamine is an aminosaccharide that acts as a preferred substrate for the biosynthesis of glycosaminoglycan (GAG chains and, subsequently, for the production of aggrecan and other ... loss. On the other hand, OPG is considered a decoy receptor that blocks the binding of RANKL to the RANK receptor, located on osteoclast precursors, thereby inhibiting the term...

Ngày tải lên: 09/08/2014, 10:21

... disruption of the mucosa barrier, thus provid- ing an easy port of entry and increase the recruitment and activation of HIV susceptible inflammatory cells. The inflammation and ulceration increases ... Health, Institute of General Practice and Community Medicine, University of Oslo, Norway, 2 Department of Obstetric and Gynaecology, Rikshospitalet University Hospital, Unive...

Ngày tải lên: 10/08/2014, 05:20

... reduce these shortcomings and the need for this is further highlighted by the findings of this study. The limitations of this study were that the data was only collected from the women's point ... sections of text for the presence of these themes. The investigators did this individually, then met and discussed the results until they reached consen- sus. Ethical...

Ngày tải lên: 10/08/2014, 05:20

... mouse gene. Using the cRNA target, the hybridization reaction mixture containing the biotinylated target cRNA was loaded into array chambers for bioarray processing as described in the manufacturer's ... in the decline in insulin sensitivity and glucose tolerance with age. J Clin Endocrinol Metab 1992, 75:1125-1132. 35. O'Shaughnessy IM, Kasdorf GM, Hoffmann RG, Kalk...

Ngày tải lên: 13/08/2014, 13:20

... placed in a seal ed polythene bag.Thecentreofthefirst15cmofthescalpendof the lock was employed in the case of the mother. Fathers’ hair as received was generally very short, less than 2 cm. There ... Uranium contamination following the battles in the town in 2004. Contamination of the parents of the children and of the environment by Uranium and other elements...

Ngày tải lên: 13/08/2014, 15:21

... by 2033. It is, therefore, increasingly important to find ways of facilitating the maintenance of physical function, health and independence and quality of life of older individuals. This in ... assessment of patterns and levels of activity, functionality, well being and perceptions of the environment. - 18 - Competing interests The authors declare that they hav...

Ngày tải lên: 14/08/2014, 08:21

... yet the ranges of baseline joint counts and disease activity in subjects enrolled in most recent trials are still remarkably similar. The introduction of a newly approved therapy into the clinic ... over the past decade in trial design in RA. These include the following: • Establishment of a clear regulatory path to demonstrate efficacy of a new therapeutic • The...

Ngày tải lên: 09/08/2014, 01:22

... slope of 1. If the center line of the signals does not have a slope of 1, there may be different rates of the incorporation of Cy3 and Cy5 dyes. The signal-correction algorithm tested whether the ... reflection of this, based on release 3.1, the microarray now only represents approximately 75% of the predicted genes. The combination of an increase in the nu...

Ngày tải lên: 09/08/2014, 20:21