Báo cáo y học: "Systematic overestimation of gene gain through false diagnosis of gene absenc" pps

... Biology 2007, Volume 8, Issue 2, Article 402 Zhaxybayeva et al. 402.5 Genome Biology 2007, 8:402 Genome Biology 2007, 8:402 Correspondence Systematic overestimation of gene gain through false diagnosis ... pseudogenes and gene remnants (regions recognizable as gene- derived only by synteny and statistically significant sequence simi- larity to the parent gene) . There is thu...

Ngày tải lên: 14/08/2014, 17:22

... Loët 1,2 1 Rheumatology Department, University Hospital of Rouen, Rouen, France 2 Inserm U519, IFRMP 23, Faculty of Medicine, Rouen, France 3 GenHotel, University of Evry-Paris VII, Faculty of Lariboisière-Saint ... and/or genetic markers. The latter have the particular advantages of being present from the onset of the disease and of remaining unchanged by therapy. To date, the...

Ngày tải lên: 09/08/2014, 06:23

... University (Grant No. 2008CL06). Author details 1 Immunology and Reproductive Biology Lab, Medical School & State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, ... experiments. (D) Effect of isotype antibody on cell migration. IS: isotype antibody; V:VEGF neutralizing antibody; BGC/STC+IS: BGC/STC cell supernatants added with isotype antibody; BGC/STC+V:...

Ngày tải lên: 10/08/2014, 05:21

... cystic lymphangioma of the mediastinum. Eur J Cardiothorac Surg 2002, 21:340. 2. Nakazato Y, Ohno Y, Nakata Y, Yamaguchi H, Hazato N, Nagasawa S, Yokoyama M, Yamada T: Cystic lymphangioma of the ... malformation Cystic hygroma Pulmonary sequestration Bronchogenic and neurogenic cysts Congenital lobar emphysema Castleman's lymphoma Thymic cyst or cystic thymoma Cystic teratoma Peri...

Ngày tải lên: 11/08/2014, 21:22

... strategy is cost-effective by reducing treatment costs caused by delayed diagnosis of nosocomial infection. One of the possible limitations of the study is the required extended study duration of ... 6 Research G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study proto...

Ngày tải lên: 12/08/2014, 20:20

... tested in parallel by a different assay yielding a posi- tive result – in fact, RT-PCR, which was used at participating centers, is currently the standard method for the diagnosis of influenza. Optimal ... of influenza. Optimal sensitivity of RT-PCR and rapid antigen tests is achieved when upper tract respiratory specimens are collected within the first few days after the onset of s...

Ngày tải lên: 13/08/2014, 19:20

... [37]. Phenotypic capacitance The phenotypic capacitance reflects the variability in a panel of phenotypes induced by deletion of non-essen- tial genes and was used directly from the Levy and Sie- gal ... expressio n level of a gene as measured by the aver- age number of mRNA copies of each transcript per cell were taken from [36]. Half-life The half-life of a gene was the half...

Ngày tải lên: 09/08/2014, 22:23

... of cellular physiology and provides a valuable resource for systems biology. In the haploinsuffi- ciency profiling (HIP) assay consisting of all 6,000 heterozygous deletions (where one copy of ... chemical-genetic profiling in yeast. Cell 2006, 126:611-625. 7. Dudley AM, Janse DM, Tanay A, Shamir R, Church GM: A global view of pleiotropy and phenotypically derived gene function in...

Ngày tải lên: 09/08/2014, 20:21

... and gyrase genes, amino acid transport genes, glutamate synthase, phosphodiesterase domain (HD/EAL) genes and also some energy metabolism genes such as the alcohol dehydrogenase and the pyruvate ... phosphorylatable Asp replaced by a glycine. Since it also lacks a proximally encoded HK, it is likely that this RR is not activated by phosphorylation. Two component system involved in ener...

Ngày tải lên: 09/08/2014, 23:20

... brain autopsy and biopsy samples found significant change in one of the genes, indicating that a substantial proportion of all expressed genes could be affected by death [10]. We surveyed gene expression ... nominal significance cutoff of 0.01 (false dis- covery rate (FDR) = 4.12%, permutation test) and 8,643 using significance analysis of microarrays (SAM) at the 5% FDR cutoff. Ou...

Ngày tải lên: 14/08/2014, 16:20