Báo cáo y học: "Prediction of effective genome size in metagenomic samples" pptx

... different ploidy levels of cells [7-9], and so any technique measuring DNA content does not nec- essarily measure genome size. In addition, DNA binding of stains used in the majority of these studies ... The exact form of c(L) is deter- mined not only by the read-length dependence of the proba- bility of sequencing a portion of a marker gene, but also by the probability...

Ngày tải lên: 14/08/2014, 17:22

... * State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. † Graduate University of the Chinese Academy of Sciences, ... fileAdditional data file 3Phylogenetic tree of UDP-glucosyl transferase family proteins involved in antisense pairsPhylogenetic tree of UDP-glucosyl transferase family pro...

Ngày tải lên: 14/08/2014, 17:22

... translo- cation and in poly(U)-directed polyphenylalanine synthesis [26,27], by preventing it from binding to the ribosome [28]. Early data showed that the phosphorylation of eEF2 was increased by very low ... members of main protein kinase superfamily, Ryazanov coined the term Ôa-kinaseÕ for this unusual group of enzymes. Further discussion of this family may be found in a recent...

Ngày tải lên: 23/03/2014, 21:20

... lymphocyte proliferation. Depletion of CD25 + cells in CB resulted in little/no change in lymphocyte prolifer- ation (p = 0.56) while depletion of CD25 + cells in PB resulted in increased lymphocyte ... Columbia University, New York, NY – M Kattan*, J D'Agostino, A Chen; Mount Sinai School of Medicine, New York, NY – H Sampson, W Shreffler; Washington University School...

Ngày tải lên: 13/08/2014, 13:22

... recently, methods were devised for predicting residues involved in protein interaction s ites in the absence of any structural reports. By analysing hydrophobicity distribution, linear stretches of ... some of the complexes or by other experimental means. CONCLUSIONS We have analysed the possibility of predicting the residues forming part of protein–protein interacting surfaces...

Ngày tải lên: 21/02/2014, 15:20

... University Berlin, Institute of Biology, Theoretical Biophysics, Berlin, Germany; 3 Humboldt University Berlin, Medical Faculty (Charite ´ ), Institute of Biochemistry, Berlin, Germany A computational ... use of it in a later phase of starvation. Increasing activity in the lower part of glycolysis (E 2 ) enhances the consumption of triose-phosphates and thus causes a rapid swi...

Ngày tải lên: 17/03/2014, 10:20

... 0.3% reduction of targeted and nontargeted isoform, respect- ively). Interestingly, an AS-ODN against EGFP, described to be effective in HeLa cells [23], was totally ineffective in inhibiting the expression ... atom may cause avid binding of the ODNs to key cellular proteins, e.g. proteins involved in mRNA translation [31,32]. The inhibition of EGFP–GSTM fusion protein expres- s...

Ngày tải lên: 31/03/2014, 15:20

... 0.2 137 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 138 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.3 Cys 0.3 139 Cys 1.18 Cys 1.18 Cys 1.18 Cys ... upstream of the ’ a’ determinant, is in close proximity to the Cys 124 residue responsible for maintaining the integrity of HBsAg antigenic loop. There had been reports of insertions be...

Ngày tải lên: 12/08/2014, 02:20

... proteins [5]. The NS5A is a multidomain phosphoprotein [6]; an integral part of the virus replicase complex[7]. It is involved in protein interactions with cellular proteins including cytokines, ... have been implemented in association rule mining including the A-priori algorithm, the frequent item set mining algo- rithm (COFI) [14]. Bioinformatics as a subdescipline of data mining ai...

Ngày tải lên: 12/08/2014, 04:20

... that virus expressed microRNAs can play significant roles in the pathophysiology of HIV infection, including latency of the virus [6,7]. Moreover a microRNA residing in the nef gene has been shown to ... occur in high frequency in microRNA precursor hairpins than in pseudo microRNA hairpins and that continuously unpaired (NNN000) ele- ments have a higher frequency in pseudo mi...

Ngày tải lên: 12/08/2014, 04:20