Báo cáo y học: "Normalization of boutique two-color microarrays with a high proportion of differentially expressed probes" ppt

... however, abundantly glycosylated and the apparent molecular mass on SDS/PAGE has been estimated to 120±140 kDa [11,12]. Human BSSL has a unique primary structure as compared to other mammalian lipases. ... and fetal pancreas and in pancreatic tumoral cell lines [35,36]. FAPP and BSSL are structurally closely related, but are distinguished by a monoclonal antibody directed towards a fuco...

Ngày tải lên: 24/03/2014, 03:21

... specificity of the arrays is increased, resulting in a lower false discovery rate. Boutique arrays can, therefore, be used as a moderately high throughput assay to systematically interrogate genes of maximal ... bias and variation caused by technical artifacts while maintaining the important biological variation of inter- est. After appropriate normalization, variation in microa...

Ngày tải lên: 14/08/2014, 17:22

... K, Arakawa T, Nakamura M, Kubosaki A, Hayashida K, Kawazu C, Murata M, Nishiyori H, Fukuda S, Kawai J, Daub CO, Hume DA, Suzuki H, Orlando V, Carninci P, Hayashizaki Y, Mattick JS: Tiny RNAs associated ... of attenuator regulation in each gene family through a systematic literature survey and comparison to the Rfam RNA family database [38] and to the RegulonDB database of E. coli tran...

Ngày tải lên: 09/08/2014, 22:23

... may also be cost savings associated with broader integration of podiatrists into the Australian surgical workforce. This may be of par- ticular relevance to toenail surgery, as simple nail avulsion with ... Gilheany 1,2 and Karl B Landorf 1,2 Address: 1 Musculoskeletal Research Centre, Faculty of Health Sciences, La Trobe University, Bundoora, Victoria 3086, Australia and 2 Depar...

Ngày tải lên: 10/08/2014, 21:23

... use and by what route. Cancer-related bone pain is a particularly difficult symptom to treat. Bisphosphonates have gained acceptance as a standard approach to bone pain in adults. In the idealized ... shock sensations, nor was there hyperalgesia or allodynia. Pain was assessed by verbal self-report as he did not want to use any of the standardized childhood pain scales, and by the nurse...

Ngày tải lên: 11/08/2014, 10:22

... Treatment, Psychology Faculty, University of Malaga, Campus de Teatinos s/n. Malaga, 29071 Malaga, Spain Full list of author information is available at the end of the article Salguero et al. BMC Psychiatry 2011, ... Posttraumatic Stress Disorder. Author details 1 Department of Personality, Evaluation and Psychological Treatment, Psychology Faculty, University of Malaga, Campus de T...

Ngày tải lên: 11/08/2014, 15:22

... hyperresponsiveness (AHR) is a functional abnor- mality characteristic of bronchial asthma [1]. AHR in asthma is defined as an exaggerated response of the airway (lower airway in particular) to a variety of nonspecific stimuli, ... Nakagome K, Dohi M, Okunishi K, Komagata Y, Nagatani K, Tanaka R, Miyazaki J, Yamamoto K: In vivo IL-10 gene delivery sup- presses airway eosinophilia a...

Ngày tải lên: 12/08/2014, 14:20

... placed in a custom-built gait arena (5’6” x 1’6”) preoperatively and again on day 5. The arena is composed of a glass floor, three transparent acrylic sides, a black acrylic back, black acrylic ... early stages of lumbar radiculopathy in the rat, and that, gait metrics and dynamics may be valuable measures in pre-clinical studies evaluating drug effectiveness. Abbreviations A...

Ngày tải lên: 12/08/2014, 17:22

... identical pattern of alveolar oedema in a function of time by using a histological examination (H&E) and assessment by wet : dry ratio. An important increase of alveo- lar oedema was observed after ... deliver toxic radicals that damage pulmonary endothelium directly or indirectly by activating caspase-3, which results in apoptosis [1,2]. Second, they can damage pulmonary endoth...

Ngày tải lên: 12/08/2014, 20:20

... of Laboratory Animals [41]. Animals were housed at the Tulane National Primate Research Center, a facility accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) ... series was amplified in the real time RT-PCR assay in triplicate for generation of the standard curve. This assay can relia- bly detect 5 copies of SIV/ml and has a linear dy...

Ngày tải lên: 13/08/2014, 13:20