Báo cáo y học: "Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics" pptx

... X-box-regulated /ciliary genes. Many, or even the majority, of these candidate ciliary genes when mutated may cause a dye filling defect. Since the majority (83 out of 93) of the candidate X-box-regulated genes in C. elegans ... bona fide X- box regulated genes in C. elegans. In fact, there are still seven dyf genes (dyf-4, dyf-7, dyf-8, dyf-9, dyf-10, dyf-11 and...

Ngày tải lên: 14/08/2014, 17:22

... outcome of up- per/lower endoscopy in outpatients with iron defi- ciency anemia. The aim of our study was to investi- gate the incidence of GI pathological findings in symptomatic and asymptomatic ... evaluate the diagnos- tic yield of endoscopy in patients with IDA and to define predictive factors of gastrointestinal (GI) le- sions causing IDA and identify clinical a...

Ngày tải lên: 25/10/2012, 11:18

... the GenePaint database, we analyzed the in situ hybridization staining pattern in the pan- creas from TS22 whole embryo sections. In sum, 601 of the genes showed informative staining, and these ... pancreas library or the duct library, stages and tissue types that were not used in the array analyses. Of 24 genes identified in the array study as enriched in endocrine ce...

Ngày tải lên: 14/08/2014, 20:22

... high concentration Next, we investigated the involvement of intracellular Zn levels in the induction of apoptosis by cotreatment of 1 l M Py and 25 l M Zn (Py/Zn treatment). Determination of trace elements in Py/Zn-treated ... observed in the presence of Py (Fig. 1A). To determine the characteristics of cell death induced by Py/Zn treatment, we counted the number of necr...

Ngày tải lên: 23/03/2014, 21:20

... comparative terms, the Kenyan estimate of 10% of the Ministry of Health budget is lower than that of the Netherlands and Table 1: Annual cost of operating and organizing psychiatric services in Kenya (1 US$ ... those borne by the health care system and the family in directly addressing the problem of MBD; and (b) the indirect costs, i.e. loss of productivity caused...

Ngày tải lên: 08/08/2014, 20:23

... signaling pathways involved in embryonic skele- togenesis and joint morphogenesis, suggesting that the artic- ular cartilage is capable of triggering a signaling machinery that may play a role in ... upregulation of BMP-2 mRNA after injury. Several factors can determine activation of BMP signaling independently of the expression of one ligand, including secretion and solubil...

Ngày tải lên: 09/08/2014, 08:22

... are obviously strictly related to reduce the risk of death and to minimize the complica- tions by excluding proximal intimal tear, removing asso- ciated aneurysmal disease and maintaining a complete distal ... imaging in the acute phase (within 14 days after the onset of symp- toms). The signs of impending rupture were determined by persisting pain despite adequate an d aggressive...

Ngày tải lên: 10/08/2014, 09:22

... of 7 Plasma levels of pro and anti-inflammatory cytokines Plasma levels of IL-6, TNF-a and IFN-g were significantly higher in patients; t he levels of the anti-infl ammatory cytokines IL-10 and ... expression of adhesion molecules of the endothelium and synthesis of other pro-inflammatory cytokines such as IL-1 and IL-6. Similar to results regarding pro-inflammatory...

Ngày tải lên: 11/08/2014, 03:20

... factors and cytokines, contributing in this way to the control of inflammation which is a hallmark of asthma pathology. Disintegrin domain might also act in concert with cystein-rich region to interfere ... activity of several members of the ADAM family [28- 31]. N-terminal domain of TIMPs and more specifically the "functional binding edge" is interacting with the...

Ngày tải lên: 12/08/2014, 14:20

... N-terminal region of HuPAR2 for binding and infectionFigure 4 Single residue and mini-region mapping of the eighteen amino acid differences in the critical N-terminal region of HuPAR2 for binding ... (solid grey) and the binding wild-type receptor (solid black line). It is clear that the QLH(108–110)KPY mutation completely abolished PERV-A SU binding. The lack of both binding...

Ngày tải lên: 13/08/2014, 05:21