Báo cáo y học: "An environmental signature for 323 microbial genomes based on codon adaptation indices" doc

... differences in codon weights between evolutionary more dominant codons and codons preferred by the translational machinery. Conse- quently, we demonstrate that differences in codon usage bias by tCAI ... mesophily, thermophily and hyperther- mophily - as previously shown based on either amino acid composition [20,21] or by codon usage [7] - we obtained an environmental signature...

Ngày tải lên: 14/08/2014, 17:22

... permutation matrix. For instance, the vicinity of connection dot O (end,)~,) is denser than that of a non-connection say (end, ). Furthermore, the nearby connections @, O, and 0, form a texture ... English Figure 3. Convolution. (a) LTP dotplot before convolution; and (b) after convolution. 2.3 Convolution and local edge detection Convolution is the method of choice for enhancing...

Ngày tải lên: 17/03/2014, 23:20

... accuracy of both amplitude and phase components. Amplitudes are generally noisier for cryo-electron microscopy, whilst phases are usually more reliable when compared to X-ray crystal- lography. The ... egulation of phycobilisome structure and gene expression by light int ensity. Plant. Physiol. 98, 1003±1010. 37. Olson, J.M. (1998) Chlorophyll organization and function in green photosynthet...

Ngày tải lên: 17/03/2014, 17:20

... events. Sensitivity comparison across methods Trio discordance is a reasonable hybrid measure of sensitivity (recall) and specificity (precision), but these two measures cannot be easily decoupled based only on ... copy numbers for a 394-marker region. Algorithm for copy number variant detection Key to our approach is the observation that CNV identifica- tion can be formulated explici...

Ngày tải lên: 09/08/2014, 20:20

... Sciences, Kingston University, Penrhyn Road, Kingston-upon-Thames. KT1 2EE, UK, 2 Faculty of Computing, Information Systems and Mathematics, Kingston University, Penrhyn Road, Kingston-upon-Thames. ... replication [10]. Treatment change decisions for patients with AIDS who are undergoing HAART are commonly based on clinical treatment history data, ideally including VL, CD4 and genotyp...

Ngày tải lên: 10/08/2014, 05:21

... hypertension, hyperlipidemia, coronary artery disease, heart failure, left ventricular ejection fraction 30%) Patient 6 Female 73 Mild 5.4 cm Arterial hypertension , chronic obstructive pulmonary ... Diabetes mellitus, arterial hypertension, renal failure (dialysis), previous CABG Patient 4 Male 74 Mild 5.5 cm Diabetes mellitus, arterial hypertension, coronary artery disease, previous CABG Pa...

Ngày tải lên: 10/08/2014, 09:22

... expression to be monitored at much finer granularities than before. The Affymetrix Exon 1.0 ST array, for example, has approximately 5.5 million features, corresponding to approximately 1.4 million ... similarly to select or prioritize based on statistical significance. Use of the exonmap infrastructure to analyse exon microrraysFigure 2 Use of the exonmap infrastructure to analyse exon...

Ngày tải lên: 14/08/2014, 07:21

... identifying amplifications and deletions in array CGH data. Bioinformatics 2005, 21:3763-3770. 25. Willenbrock H, Fridlyand J: A comparison study: applying seg- mentation to array CGH data for downstream ... sensitivity and specifi- city when determining aberration, especially under condi- tions that are likely to apply in real gene expression maps. Delineation performance We next assessed...

Ngày tải lên: 14/08/2014, 08:20

... biochem@ochhades.chemie.uni-karlsruhe.de Abbreviations: PAL, phenylalanine ammonia-lyase; HAL, histidine ammonia-lyase; MIO, 3,5-dihydro-5-methylidene-4H-imidazol-4-one. Enzymes: histidine ammonia-lyase (EC 4.3.1.3); phenylalanine ammonia-lyase ... Germany; 2 Institute for Organic Chemistry, Budapest University of Technology and Economics, Hungary The plant enzyme phenylalanine ammonia-lyas...

Ngày tải lên: 08/03/2014, 23:20

... undergo cardiac surgery, the evaluation of the thymus is often considered secondary and tumoral disease of the thymus is only considered when a mass is found intraoperatively or at a CT scan. Few ... status postoperatively to confirm the suspected concomitant T- MG. Consent The written consent for publication was obtained. A copy of the written consent is available for review by the Edito...

Ngày tải lên: 10/08/2014, 10:20