Báo cáo y học: "A model worth considering" pdf

... a healthy adult. But that isn’t the main reason that Scott Johnson is a man in a hurry. He’s in a hurry because he thinks he’s figured it out, and when you think you’ve figured it out, you’re ... he says. He came up with a different model. The Myelin Repair Foundation set about finding a way to accelerate the basic science necessary to achieve its goal of licensing at least one myelin ... G...

Ngày tải lên: 14/08/2014, 17:22

... a three-dimensional model of the ligand binding domain (LBD) of the mouse aryl hydrocarbon receptor (mAhR). The model allowed us to putatively i dentify the residues responsible for the recognition of polychlorinated ... by AhR receptors and to formulate an hypothesis on the signal transduction mechanism. Keywords: aryl h ydrocarbon receptor; polychlorinated dibenzo-p-dioxins; structure p...

Ngày tải lên: 24/03/2014, 00:21

... part, mediated by IL-1 and/or TNF-α. Oncostatin M (OSM), a cytokine produced by activated T cells and macrophages, is structurally and functionally related to the IL-6 cytokine family. Raised levels ... Shaughnessy SG: Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: synergy with dexamethasone. Cytokine 2...

Ngày tải lên: 09/08/2014, 06:22

... pool with NHS-cyanine dyes (Cy3 and Cy5; Amersham Biosciences, Amersham Place, England). The two labeled probes were hybridized with the array for 16 h at 65°C. Arrays were scanned by using a 4000B ... with those previously obtained in other human cell lines by microarray analysis [9] and by massively parallel signature sequencing [32]. We have observed that the major- ity of genes are expres...

Ngày tải lên: 09/08/2014, 08:22

... Biology and Medical Modelling Open Access Research A model analysis of static stress in the vestibular membranes Daniel J Pender Address: Department of Otolaryngology, Columbia University Medical ... chambers. Discussion Models have long been used to gain insight into the behavior of complex and unwieldy physical systems [11]. Dynamic vestibular models concerned with endolym- phatic flow a...

Ngày tải lên: 13/08/2014, 16:20

... probability P(relative is in genotypic risk category y| proband is in genotypic risk category x). Similarly, define E xy as the conditional proba- bility P(relative is in environmental risk category y| proband ... potentially the whole genetic sequence, on dis- ease susceptibility (here called 'genotypic risk') may be important. The four-category model of population risks devel...

Ngày tải lên: 13/08/2014, 16:21

... HV: Transduction of intracellular and intercellular dynamics in yeast glycolytic oscillations. Biophys J 2000, 78:1145-1153. Theoretical Biology and Medical Modelling 2006, 3:12 http://www.tbiomed.com/content/3/1/12 Page ... oscillators based on metabolic pathways have also been described. Almost 40 years ago, Chance and col- leagues described oscillations in glycolytic pathways both in yeast...

Ngày tải lên: 13/08/2014, 23:20

... 9(3):155-172. 51. Dyck PJ, Nukada H, Lais AC, et al: Permanent axotomy: a model of chronic neuronal degeneration preceded by axonal atrophy, myelin remodeling, and degeneration. In Peripheral Neuropathy. Edited ... Brain Res 1985, 340(1):19-36. 38. Dyck PJ, Lais AC, Karnes JL, et al: Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination. Ann...

Ngày tải lên: 10/08/2014, 10:20

... collaborative care model be implemented. Decision criteria vary widely across facilities, but may include the projected quality of care benefits for the facility's population; the feasibility of implementation, ... may be a seemingly simple course of action, but is rarely effective [2-4], especially because cli- nicians have a strong occupational culture and enjoy a high degree of prof...

Ngày tải lên: 11/08/2014, 05:21

... Holocarboxylase synthetase (biotin-[proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) 47 D00943 MYH6 Myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic ... recom- mended by the manufacturer. Analysis by flow cytometry was accomplished on a FACS Calibur automated bench- top flow cytometer. Data obtained by flow cytometry was analyzed by non-parametric ....

Ngày tải lên: 11/08/2014, 08:21