Báo cáo y học: "Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors" pps
Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx
... stability of serum creatinine and platelet counts was associated with significantly increased 28-day mortality. Second, early treatment with DrotAA (within 24 hours of onset of sepsis -associated ... observa- tional study, also found that early treatment with DrotAA (within 12 hours of first organ dysfunction) was associated with a lower risk of death [28]. Factors ass...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "HLA class II DR and DQ genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient" pptx
... nature of the susceptibility and/or protective alleles. Several years ago these discrepancies could have been associated with different types of laboratory methods, but they may also be partly because ... changed; cur- rently, the inflammation of cardiac valves is accompanied by Sydenham's chorea, but without laboratory activity of inflam- mation. Also, during the course of...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Exome sequencing identifies a novel missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegia" docx
... the existence of pigmen- tary degeneration of the retina and gonadal atrophy. The initial symptom of progressive h eari ng loss began at age 16 years. Depressive mood, anxiety and hypochondriacal complaints ... encephalopa- thy [23] (MIM 603041) associated with homozygous or compound heterozygous rare variants in RRM2B have been reported. More recently, two families with adPEO d...
Ngày tải lên: 09/08/2014, 23:20
Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx
... 3.6 HIVGrade NNRTI HIVGrade Resistant Intermediate Sensitive Phenotype g eno2pheno Vircotype Figure 2 The “ resensitizing” effect of 76V could be observed in a variety of other patients before start of PI-containing therapy. Genotypic and phenotypic data of ... 96 weeks of follow-up therapy Group Patient ID Protease mutations at start of therapy Time of therapy failure Time of...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: " Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization" pdf
... on days 1 and 14, followed by intranasal challenge (i.n.) on days 25, 26, and 27 with 25 µl of allergen extract: (12.5 µg Af in 21% glycerol/ PBS). Limulus lysate assay (Limulus Amebocyte Lysate ... analysis of the BAL cytokine profile) or a large volume (5 ml of sterile saline for analysis of the sur- factant protein profile). The amount of liquid retained after BAL was an averag...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration" doc
... influenced by norepinephrine, improving cellular oxygen delivery, although mitochondrial dysfunction may occur even in the absence of tissue hypoxia [23,34]. A third imitation is the lack of liver ... stroke work index, heart rate and systemic oxygen delivery. However, it was not associated with changes in systemic oxygen consumption, lactate concentrations, capillary blood flow, ur...
Ngày tải lên: 13/08/2014, 11:22
Báo cáo y học: "Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors" pps
... Article R113 Research Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors Margarida Gama-Carvalho * , ... immunoprecipitation and microarray analysis, we identify subsets of mRNAs that associate differ- entially with U2AF 65 and PTB, corresponding to approx...
Ngày tải lên: 14/08/2014, 17:22
Tài liệu Báo cáo Y học: Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA pdf
... that two methyl groups are always introduced, one slowly by Dnmt3a or by de novo methylation catalyzed by Dnmt1 and the second one very fast. Therefore, this effect can only double the rate of ... Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA. J. Mo...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo y học: "The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma" potx
... patient may have had a variant of a lymphocytic hypereosinophilic syndrome given the systemic eosinophilia, modestly high levels of sputum IL-5 and serum TARC and raised serum total IgE early in the ... of hypereosinophilic syndrome. J Allergy Clin Immunol 2010, 126:45-9. 9. Ravoet M, Sibille C, Gu C, et al: Molecular profiling of CD3-CD4+ T cells from patients with the lymphocytic...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx
... staining of a hyperplastic RA synovial lin- ing cell layer. This staining was typical of most areas of RA synovium where the lining was hyperplastic. (h) An area of an RA synovial lining layer that ... positively (arrow). (e) Intense staining of individual cells in the lining layer of a typical OA synovium. (f) An area of an OA synovium demonstrates a lining layer completely...
Ngày tải lên: 09/08/2014, 10:20