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Báo cáo y học: "Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome " pps

Báo cáo y học:

Báo cáo y học: "Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome." pps

... nesting, partly because of limitations in accu-rately joining fragments of a TE insertion that becomeseparated in the genome by a subsequent nested TE insertion, and partly because analysis of ... of TE-rich heterochromatic sequences, but canevolve in situ by the joint action of recurrent transposition and duplication. Finally, we analyzed in detail the patterns of TE nesting in the genome ... eachother by approximately 45 Kb of other TE and unique sequences, with the most distal copy found in the intron of the gene CG40500. No evidence of tandem duplication can beobserved in comparisons...
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Báo cáo y học: "Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan" potx

... Ploidy703 of 1,173 tumors were available to examine the status of DNA ploidy using flow cytometry by following the method of Dressler et al.[24].TheDNAindex(DI),representing the ratio of the ... respectively. On the other hand, right-sided colon cancer had, 16.3% and 11.2% MSI-H and MLH1 methylation, respectively. Therefore, dysfunction of MMR proteins might play different roles in the tumor-igenesis ... markers in the drug therapystudies. The major discrepancy, and argument, betweenour results and other studies was that the proporti on of MSI-H in our study was only 6.4%, lower than that of previous...
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Báo cáo y học: "DHEA-dependent and organ-specific regulation of TNF-α mRNA expression in a murine polymicrobial sepsis and trauma model" pps

... drafted the manuscript. FH and CK participated in the interpretation of data. MG carried out the design of the study, scored the activ-ity of mice and contributed to the interpretation of data.Acknowledgements The ... could be interfered by IGF-I, and thata variety of cytokines and growth factors play a role in the mod-ulation of hormone secretion [37,38]. This could result in time-dependently varying reactions ... normalized by calculating the quo-tient of the amount of TNFα mRNA against the amount of mRNA of the housekeeping gene GAPDH. * P ≤ 0.05. The data are expressed as mean ± standard error of the mean....
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Báo cáo y học: "Decreased catalytic function with altered sumoylation of DNA topoisomerase I in the nuclei of scleroderma fibroblasts" ppsx

... SUMO1transfection, which indicates a higher efficiency of catalytic function of topo I after SUMO1 inhibition in the fibroblasts. According to the intensity of the bands of remaining supercoiled DNA in serial ... to quantify the intensity of the bands. A total of 11 pairs of SSc and control fibroblast strains were examined with this assay.ImmunostainingSSc and normal fibroblasts were grown in culture ... gel, and then stained withethidium bromide. The catalytic activity of topo I wasdetermined by measuring the intensity of the super-coiled DNA bands after reactions with a serial dilutionof...
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Báo cáo y học: "A semi-quantitative GeLC-MS analysis of temporal proteome expression in the emerging nosocomial pathogen Ochrobactrum anthrop" pptx

... alpha chainSuccinyl-coa synthetase beta chainPhosphoribosylformylglycinamidine30S ribosomal protein S1930S ribosomal protein S18Glutamine synthetase IGMP synthase (glutamine-hydrolyzing)30S ... essential element in the regulatorycycle of oxyR, which may explain the presence of N-methylhy-dantoinase in late phase growth, as it is an integral part of the γ-Glutamyl pathway, which is ... boxed in yellow.Additional data file 1Superpathway of glycolysis, pyruvate dehydrogenase, TCA and the superpathway of the glyoxylate cycleProteins unique to the early growth phase are boxed in...
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Tài liệu Báo cáo Y học: Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenol pyruvate carboxykinase determined by fluorescence spectroscopy pdf

Tài liệu Báo cáo Y học: Ligand interactions and protein conformational changes of phosphopyridoxyl-labeled Escherichia coli phosphoenol pyruvate carboxykinase determined by fluorescence spectroscopy pdf

... points to changes in the dynamicalproperties of the local environment of the P-pyridoxylgroup due to changes of the protein conformation inducedby the binding of PEP or the ternary combination.Quenching ... characteristics of the native protein, allowing the determination of several pro-tein–ligand dissociation constants, as well as the role of Mg2+ and Mn2+ in substrate binding. The binding affinity of PEP ... transfer of the c-phosphoryl group of ATP to yield PEP, ADP, and CO2. The interaction of the enzyme with the substrates ori-ginates important domain movements in the protein. In thiswork, the interaction...
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Báo cáo Y học: Spectroscopic characterization and ligand-binding properties of chlorite dismutase from the chlorate respiring bacterial strain GR-1 ppt

Báo cáo Y học: Spectroscopic characterization and ligand-binding properties of chlorite dismutase from the chlorate respiring bacterial strain GR-1 ppt

... Electronspinresonancestudyoftheroleofnitricoxideandcatalaseintheactivation of guanylate cyclase by sodium azide and hydro-xylamine. Modulation of enzyme responses by heme proteins and their nitrosyl ... the binding of hydroxide and imidazole to the ferric enzyme and of NO to the ferrous enzyme to establish the nature of the proximal ligand bound to the heme iron center. We alsostudied the binding ... hydrogen peroxide binds.Possibly hydrogen peroxide oxidizes the ferric iron center of chlorite dismutase, as it does in metmyoglobin [10]. In the case of myoglobin, as with many heme proteins,...
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Báo cáo y học: "Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitus" ppsx

... refer their tinnitus (5-6 cm in above the entrance of auditory meatus on straight line to the vertex). With the intensity of the stimulation set at 90% of the motor threshold, the site of maximal ... not perceived, and both tinnitus pitch and tinnitus intensity (above hearing threshold) are matched to the perceived tinnitus. Technical investigations include MRI of the brain and posterior ... non-invasive tool capable of modulating human brain activity, using single pulse or burst stimuli. Burst rTMS has only been performed in the theta range, and has not been used clinically. The...
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Báo cáo y học:

Báo cáo y học: "Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages" docx

... cytokines rather than TLR-ligand binding per se. The results of our study demonstrate that several pro-inflammatory cytokines contribute to the regula-tion of TLR expression. Of the cytokines ... TLR2 and TLR4 were up-regulated by GM-CSF and IFN-γ in monocytes, TLR5 expression was diminished by these cytokines in monocytes and by GM-CSF in neutrophils. These results may high-light the ... expression. Pro-inflammatory cytokines may also control protein ex-pression of TLRs on the cell surface and intracellularly through regulation of inhibitory RNA pathways, pro-tein translation and post-translational...
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Báo cáo y học: "Anti-tumorigenic and Pro-apoptotic effects of CKBM on gastric cancer growth in n" potx

... Panax ginseng: a role in cancer therapy? Integr Cancer Ther. 2003, 2:13-33. 4. Shin JY, Song JY, Yun YS, Yang HO, Rhee DK, Pyo S. Immunostimulating effects of acidic polysaccharides extract of ... University of Hong Kong prior joining the company. He had been the founding Editor and Editor -in- Chief of Biological Signals and Biological Signals and Receptors, Adjunct Professor of University of ... is therefore possible that CKBM could induce cytokine release including TNF-α in these animals and inhibit tumor growth. However, further study is needed to determine how they are induced and...
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