Báo cáo y học: "ProCAT: a data analysis approach for protein microarrays" pot

... these artifacts are variable, it is necessary to manually flag these spots initially and then remove them from future analysis. Many commercially available software pack- ages for microarray experiments ... test arrays and negative control arrays for one particular assay. Data file format describes the layout in the uploaded dataset so that ProCAT can recognize and extract the useful i...

Ngày tải lên: 14/08/2014, 17:22

... [http://www.ebi.ac.uk/ena/ data/ view/ERP000619]. 28. Affymetrix - Sample Data, Exon 1.0 ST Array Dataset [http://www. affymetrix.com/support/technical/sample _data/ exon_array _data. affx]. 29. Akira S, Takeda ... Access ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data Brad A Friedman 1,2,3* and Tom Maniatis 4 Abstract RNA-Seq and...

Ngày tải lên: 09/08/2014, 23:20

... cutoff, 'array density' of the peak, and the P value for that peak. The array density value is defined as the average number of arrayed elements used to calculate the window values for all ... ChIPOTle can estimate the P value for a region using a permutation-based approach (Additional data file 2). Using ChIPOTle Detailed instructions for the installation and use of...

Ngày tải lên: 14/08/2014, 15:20

... (data available upon request). The data were collected from the three major micro- array databases: Stanford Microarray Database [39], Gene Expression Omnibus [40], and ArrayExpress [41]. Addition- ally, ... framework DISTILLER to a combination of publicly available microarray data and regulatory motif data. This allowed us to considera- bly extend the transcriptional network with nov...

Ngày tải lên: 14/08/2014, 21:20

... it appeared that a relatively recent duplication had occurred in the ancestors of Lepidoptera and Diptera around 300 million years ago, and that tim had evolved rapidly to take on a dedicated ... provide a valuable resource for the detailed analysis of differences in gene expression between these castes. Early data from relatively small cDNA libraries already indicate major differ...

Ngày tải lên: 14/08/2014, 17:22

... operation. Additional data file 2 contains the results obtained by GENE- CODIS in the analysis of the yeast and human gene sets. Addi- tional data file 3 provides a description of a comparative analysis ... current applications for functional pro- filing essentially use the same general approach and generate statistical scores for single annotations. They mainly differ on as...

Ngày tải lên: 14/08/2014, 17:22

... overall, disadvantageous to the study because such an approach would not allow us to study important interactions between age and other covariates. Unfortu- nately, data on the temporal sequence ... University, Palo Alto, California, USA 2 Jyväskylä Central Hospital, Jyväskylä, Finland 3 Vanderbilt University, Nashville, Tennessee, USA Corresponding author: Eswar Krishnan (e-mail: eswar_k...

Ngày tải lên: 09/08/2014, 01:21

... It’s exactly what the people who developed SAPS [Simplified Acute Physiology Score] and APACHE [Acute Physiology and Chronic Health Evaluation] really wanted – to try to find a way to give a global ... more potential you have to get out of it. Obviously, continuous variables give you more information than dichotomous variables when you use statistical analysis, and at this stage we’re st...

Ngày tải lên: 12/08/2014, 19:22

... standard anticoagulants For a hypothetical example anticoagulant prophylaxis RCTs, consider acutely ill patients admitted to hospital medical wards. America n Association of C hest Physician (ACCP) ... FPE rate ma y appear to be the logical primary efficacy endpoint for RCTs comparing standard anticoagulant prophylaxis and treatment with a low VTE risk diet, FPE data are unreliabl...

Ngày tải lên: 13/08/2014, 16:20

... descriptor arrays for the best separation through a linear programming formulation. I also described a data structure that exploits all available memory to search for all similar small molecules to a ... of a regulatory network by treating it as a Boolean logic circuit that can work synchronously or asynchronously. The idea makes a lot of sense, as most of the available dat...

Ngày tải lên: 14/08/2014, 17:22