Báo cáo y học: "BoCaTFBS: a boosted cascade learner to refine the binding sites suggested by ChIP-chip experiments" pot

... sum of all the nodes is +0.803, a confident score indicating that this is predicted to be a binding site. AACAGGAATA ATCAAGACAT TTCACGAATG …… …… ACGTCGATAC Binding sites GAGATGACAA CTAATCGAGC TTCCTCGATG …… ... 7:R102 Boosted cascadeFigure 9 Boosted cascade. (a) Flowchart of training a cascade of classifiers. (b) Detection cascade. A series of classifiers are applied...

Ngày tải lên: 14/08/2014, 17:22

... despite the inability of these mice to metabolize galactose via a classical Leloir pathway, they lack severe pathologies associated with galactosemia in humans, and are phenotypically normal [ ... R84 Software MouseCyc: a curated biochemical pathways database for the laboratory mouse Alexei V Evsikov, Mary E Dolan, Michael P Genrich, Emily Patek and Carol J Bult Address: The Ja...

Ngày tải lên: 09/08/2014, 20:20

... list has been extensively annotated and linked-out to other databases. Incyte and the NIH have made the platform available to the community via academic microarray facilities selected by an NIH ... can measure dye effects by averaging the two ratios (Cy3 sample A/ Cy5 sample B and Cy3 sample B/Cy5 sample A) to obtain an axial symmetry of reflection (ASR). Calculated ASR va...

Ngày tải lên: 09/08/2014, 20:21

... parenchyma of the inflated IPF and COPD lung is calculated against the surface area, the values in the COPD lung remain low which is the n related only to the large e mphysematous areas in the COPD ... analysis and drafted the manuscript. SO carried out the proteomic analysis and participated in creating the figures. KS participated in the analyzing immunohistochemical...

Ngày tải lên: 12/08/2014, 11:22

... for nasal lavage was performed according to a method described by Wihl and co-workers [41]. Each nasal cavity was lavaged separately with a syringe (60 ml) to which a plastic nasal olive was connected ... example, nasal inflammation as evaluated by an increased influx of inflammatory cells into the nasal airway and increased IL-8 levels, has been described in persons occupatio...

Ngày tải lên: 12/08/2014, 18:21

... To avoid bias by repeating analysis of data from the same patient, each patient was included only once in the statistical analysis. In addition, we wished to focus on the age of the children and ... accordance with the COMFORT classification. Data are expressed as mean ± standard deviation in the case of a normal distribution and interval scaling level, and as median (rang...

Ngày tải lên: 12/08/2014, 20:20

... and by average mutual information. For every U(t) there is an associated indicator signal V(t), and since we have already totally characterized the state of the neuron by U(t) there must be a ... into the cytosol inevitably perturbs the time-course of free cytosolic calcium by acting as a buffer, thus altering the quantity to be measured. To address this, traditional a...

Ngày tải lên: 13/08/2014, 16:21

... that are located further away, with the weight approaching zero at the boundary of the kernel. Thus, the transition to the boundary represents a fuzzy rather than sharp boundary [53] and can ... theo- retically-informed rather than data-driven analytical approaches [75]. Acknowledgements LT is currently supported by an Australian National Health and Medical Research Council (N...

Ngày tải lên: 14/08/2014, 08:20

... that the discovery of MCPyV by Chang and Moore and their team [11] has opened up important new avenues that should illuminate MCC biology and also that the DTS technique may be applicable to the ... with a circular double-stranded DNA genome of approximately 5 kb. It has been well established that many polyomaviruses are able to transform mammalian cells [14]. The best- charac...

Ngày tải lên: 14/08/2014, 08:21

... Abeygunawardena N, Coulson R, Farne A, Holloway E, Kolesnykov N, Lilja P, Lukk M, Mani R, Rayner T, Sharma A, William E, Sarkans U, Brazma A: ArrayEx- press - a public database of microarray experiments ... 7:R37. 20. Tanay A, Sharan R, Kupiec M, Shamir R: Revealing modularity and organization in the yeast molecular network by integrated analysis of highly heterogeneous genomewide d...

Ngày tải lên: 14/08/2014, 21:20