Báo cáo y học: "Do the math" pptx

... completed, they knew it was time to devote themselves primarily to teaching others, because they simply wouldn’t be able to do cutting- edge stuff any more. The peculiar nature of mathematics ... But with very few exceptions, any of them can improve their understanding of the subject if they keep working at it. Progress can be frustratingly slow in some cases, but it’s nearly always there...

Ngày tải lên: 14/08/2014, 17:22

... reductase inhibitors The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG- CoA) reductase catalyses the conversion of HMG-CoA to mevalonic acid and is a rate-limiting step in the cholesterol biosynthetic pathway. Statins ... clinically on the basis of their capacity to suppress cholesterol biosynthesis and thereby modify an important vascular risk factor. Numerous clinical studies ha...

Ngày tải lên: 09/08/2014, 06:22

... included non synonymous substitution rate, synonymous substitution rate, and non synonymous/synony- mous rates of substitution (from the Ensembl website [75]). Regional Alu content similarity To correct ... analysis In the case of Bodymap data, there were very few gene pairs in which the human copy was housekeeping and the mouse counterpart was tissue specific and vice versa. We there...

Ngày tải lên: 14/08/2014, 08:20

... catalytic activity proceed essentially by the same mechanism. Indeed, catalytic residues occupy the same position in the 3D structures of the two enzymes. In addition, the p redicted secondary structures ... function, display only one polar cavity in the vicinity of the conserved catalytic Asp re sidue. Keywords: neurospora; P-ATPase; homology model; cavity; H + . The 3D struc...

Ngày tải lên: 23/03/2014, 21:20

... previously described [9,15]. MALDI-TOF/MS was performed on a Perseptive DE-RP (Applied Biosystem) using a-cyano-4-hydroxycin- namic acid as matrix. Lethality assay in mice The in vivo toxicity of ... venoms and become key molecular probes for the characterization of these channels. They are usually small basic polypeptides (between 30 and 70 amino acids), cross-linked by three or four dis...

Ngày tải lên: 23/03/2014, 21:20

... FEBS plasticity, between the F 1 and F o complexes, and the switching between tight and weak affinity may play a role in the coupling activity of the enzyme in some ATP synthases. Presently, there is ... binding to empty chip), allowing the elimination of the latter by baseline correction (see below). As a result of the location of the His tag on the very top of the c¢ sub-...

Ngày tải lên: 24/03/2014, 00:21

... when studying the catalytic efficiency for these mutants in the diaphorase reaction, all of them yield values very close to those of the wild-type enzyme at the different ionic strengths assayed (within ... FNR the side-chain of E139 might influence the properties of the flavin, assuming some of the functions carried out by E301 in the wild-type enzyme [22]. In this context, a...

Ngày tải lên: 31/03/2014, 08:20

... analysis they determined the binding free energy, enthalpy and entropy of the ubiquinone to the Q B -site. Methyl substituted 1,4-naphthoquinones have gained substantial i nterest a s they bind ... 2M3UNQ 2,5-Dimethyl-3-undecyl-NQ 25DM3UNQ 2,6-Dimethyl-3-undecyl-NQ 26DM3UNQ 2,7-Dimethyl-3-undecyl-NQ 27DM3UNQ 2,8-Dimethyl-3-undecyl-NQ 28DM3UNQ 2,5,8-Trimethyl-3-undecyl-NQ 258TM3UNQ 2,6,7...

Ngày tải lên: 31/03/2014, 21:21

... chromosomes. The fidelity of chromosome transmission is enhanced not only by the geometry of stable centromere–MT interac- tions, but also by the action of a centromere-based regulatory system called the ... way, the critical connections that hold sisters together from S phase through early mitosis are literally cut by Ômolecular scissorsÕ in the form of Esp1/separase at the onse...

Ngày tải lên: 31/03/2014, 21:21

... SUMMARY Fourty two supratentorial first-ever ischemic stroke patients with severe hemiparesis were included. Functional recovery was assessed with the Barthel activities of Daily Living ... quả 6 tháng. Barthel 6 tháng = 80,5 - 1,2 x + 16 y + 23,3 z MRC 6 tháng = 1,38 - 0,043 x + 1,1 y + 1,4 z (Chú thích: * x: tuổi; * y: MEP (y = 1 khi không ghi đợc MEP; y = 2 khi ghi đợc...

Ngày tải lên: 07/08/2014, 00:23