Báo cáo y học: "Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression" pptx

... characterized miRNAs are involved in developmental regulation, including the timing and neuronal asymmetry in worm; growth control and apoptosis in fly; brain morphogenesis in zebrafish; and hematopoetic and ... and reproduction in any medium, provided the original work is properly cited. Neuronal gene expression control<p>Using comparative sequence analysis...

Ngày tải lên: 14/08/2014, 17:22

... In turn, insulin resistance is associated with many troublesome, age-related perturbations including hypertension, dyslipidemias, diabetes, obesity and even premature aging [4-7]. Yudkin and ... sodium and water intake in the mouse. Am J Physiol Regul Integr Comp Physiol. 2003; 284:R1380-1381. 40. Krieger DR, Landsberg L. Mechanisms in obesity-related hypertension: role of...

Ngày tải lên: 08/08/2014, 16:23

... of introns present in fungal ancestors or to intron gain into ancestrally intron-poor genes. Many intron positions are shared between eukaryotic king- doms. In particular, many intron positions ... maydis in blue, U. maydis in purple, zygomycete R. oryzae in orange, vertebrates in pink, and green plant A. thaliana in light green.Click here for fileAdditional data file 2The phy...

Ngày tải lên: 14/08/2014, 08:20

... ly sis cassette (endoly sin, holin, and a lysis accessory protein) were detected in these phages and no sequence similarity to lysogenic phages or to any compone nt that is associated with lysogeny such ... helicase protein belonging to the SNF2 family, commonly found in proteins involved in a variety of processes including tran- scription regulation, DNA repair, DNA recombination...

Ngày tải lên: 11/08/2014, 21:21

... is important to understand the activity of enzymes of different subtypes. In our study, subtype B and C integrase enzymes were evaluated; and the activity of integrase inhibitors against them ... processing activity compared to strand transfer [18,22,23]. Purified recombinant subtype B and C integrase enzymes were incubated with increasing concentrations of inte- grase inhibitors and...

Ngày tải lên: 12/08/2014, 23:22

... was incubated with the recombinant subtype B and C RT enzymes in assay buffer as described in Materials and Methods. RNase H cleavage was initiated by the addition of MgCl 2 and analyzed by monitoring ... of HIV-1 subtype B and subtype C recombinant RTs and viruses to RT inhibitors To test whether NRTIs and NNRTIs have similar inhibi- tory effects on HIV-1 subtype B and C RT...

Ngày tải lên: 13/08/2014, 01:20

... determined using SAM [23]. Probes were annotated using the Web-based Affymetrix NetAffx analysis tool [56] and Ingenuity Pathway Analysis (Ingenuity, Moun- tain View, CA). NIA microarray sample and ... ng/ml hBMP-4 and 10 ng/ml hFGF2 from day 1 to day 6, 10 ng/ml mFGF-8b and 10 ng/ml hHGF from day 6 to day 9; and 10 ng/ ml human oncostatin M and 10 ng/ml hHGF from day 9 to day...

Ngày tải lên: 14/08/2014, 08:20

... deposi- tion; annotation of clip-domain SPs/SPHs, serpins, spätzles, SRs and others; Toll and Imd pathways. Jay Evans: RT-PCR analysis; GNBPs and PGRPs. Zhiqiang Lu: C-type lectins, galectins, TEPs and ... sequence diversity and inhibitory selectivity. Intracellular signal pathways and their regulation Drosophila Toll is a transmembrane protein that binds spät- zle and relays...

Ngày tải lên: 14/08/2014, 08:20

... for only 22 amino acids, including the amino acids selenocysteine and pyrroly- sine whose incorporation into protein requires the reassign- ment of the UGA and UAG stop codons, respectively [1,2]. This ... methodology proposed here is that its theory of inference is well known, yielding an analysis that is more sequential, more easily interpretable and with more complementary tools...

Ngày tải lên: 14/08/2014, 14:21

... seedlings. Transcript profiling and bioin- formatic analyses are leading to a better understanding of the cis and trans factors that control these rhythmic changes in transcript abundance; in particular, ... signaling pathways that we have examined. These new findings suggest most aspects of plant physiology are influenced by the circadian system and will help to lead us to a mechan...

Ngày tải lên: 14/08/2014, 20:22