Báo cáo y học: "Regulatory RNAs and the demise of ‘junk’ DNA" potx

... known about their function. Now Piwi proteins have themselves been linked to small RNAs, but little is known of the function of these piRNAs. They are perhaps the first of many new classes of RNA ... USA) reported the discovery of a new class of thousands of testis- specific, 30-mer RNAs, named piRNAs, that associate with proteins of the Piwi subfamily of Argonaute...

Ngày tải lên: 14/08/2014, 17:22

... with their pets need not represent any risk for infection with Toxoplasma gondii. Cats are the definitive host of T. gondii; they are the only animals that pass oocysts in their feces. They become ... Veterinarians are often faced with the need to explain to their clients that it is not necessary, for example, to give away one’s cat during pregnancy and that if they follow a fe...

Ngày tải lên: 03/11/2012, 11:06

... calculation, namely stationarity and periodicity. Note that the square of the contribution of each frequency is the power of that frequency to the total spectrum, and the total power of spectral analysis (area ... from the properties of the parts, and they depend on the integrity of the whole; the systemic prop- erties vanish when the system breaks apar...

Ngày tải lên: 12/08/2014, 20:20

... multicollinearity, and estimates of adjusted R square and F statistics of the regression model [61]. Sensitivity analysis Sensitivity of the results to imputation of missing data was explored by running the ... for their efforts in gathering cost data at the country level; and Tessa Tan Torres for her input in the development of the methods used. The work repr...

Ngày tải lên: 13/08/2014, 11:22

... in the synovium of patients with RA and considered of importance in the migration of cells to the synovium (reviewed in [20]). A recent study by Kop and colleagues show that neutralisation of ... restores their suppressive function [73,74]. Eliminating TNFα by antibody therapy might therefore be beneficial not only by directly suppressing proinflammtory processes but also by...

Ngày tải lên: 09/08/2014, 10:22

... Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany and 2 Evolutionary Biology and Ecology, Department of Biology, University of York, York YO10 5YW, UK References 1. ... location of the human and chimp hits for each read is verified by using liftover [50] to map the coordi- nates of the human hit to the chimpanzee genome and the coo...

Ngày tải lên: 09/08/2014, 20:22

... treatment was up to 10 days. Primary objectives were to determine the safety and efficacy of G-CSF in this patient population and the effect on the time to resolution of morbidity [25] (TRM), which ... trial in the USA, Canada, and Australia. Patients were randomized to receive 300µg/day of G-CSF subcutaneously or placebo in addition to conven- tional antibiotic therapy....

Ngày tải lên: 12/08/2014, 18:20

... comorbidity. Patients with psychiatric illness may not have routine general medical care and diagnosis of general medical conditions may be delayed. As the physician with the most (and often the only) ... for symptoms of cardiac pathology, such as recurrent syncope. A family history of early sudden death should be obtained and serum electrolyte imbalances should also be corre...

Ngày tải lên: 25/10/2012, 10:51

... (PLP)-dependent enzyme which catalyses the b,c- hydrolytic cleavage of the amino acids L -kynurenine (1 )and L -3-hydroxykynurenine (2)togive L -alanine (3) and either anthranilic acid (4) or 3-hydroxyanthranilic ... pathophysiology of human diseases has always been hampered by the availability of human tissue, aesthetics, and ethical considerations. The principle aim of...

Ngày tải lên: 08/03/2014, 22:20

... recent analysis of the interaction between CCT and b-tubulin by cryoelec- tron microscopy allowed the identification of three regions from the N-terminal, and five from the C-terminal domains of b-tubulin, ... lane and the arrow indicates the position of the b-tubulin/CCT complex. (B) The amounts of the tubulin bound to CCT were quantitated by the use of a...

Ngày tải lên: 23/03/2014, 21:20