Báo cáo y học: "Primate-specific evolution of an LDLR enhancer" potx

... Australia. 6 Department of Molecular and Cell Biology, Center for Applied Genetics and Technology, University of Connecticut, Storrs, CT 06269, USA. 7 Faculty of Veterinary Science, University of Sydney, Sydney, ... Williams 25 , Yogi Sundaravadanam 25 ,DonnaMMuzny 24 , Shalini N Jhangiani 24 , Lora R Lewis 24 , Margaret B Morgan 24 , Geoffrey O Okwuonu 24 ,SanJuanaRuiz 24 , Jireh San...

Ngày tải lên: 09/08/2014, 23:20

... numerous Human LDLR PS2 enhancer exhibits significantly higher activity than orthologous lemur, mouse, and dog enhancersFigure 2 Human LDLR PS2 enhancer exhibits significantly higher activity than orthologous ... Access 2006Wanget al.Volume 7, Issue 8, Article R68 Research Primate-specific evolution of an LDLR enhancer Qian-fei Wang ¤ *† , Shyam Prabhakar ¤ *† , Qianben Wang ‡ ,...

Ngày tải lên: 14/08/2014, 17:22

... monomeric and dimeric prototypes for the respective families of c-andb-crystallins, andsimplyreferredtoasc-type or b-type crystallins, respectively. Both monomeric c-type crystallin and the subunit of dimeric ... acquisition of an interdomain intron in the evolution of c-crystallins, and of both interdomain and intermotif introns in the evolution of b-type crystallin genes (...

Ngày tải lên: 24/03/2014, 04:21

... the transcriptional activity of promoters bearing SBEs. In addition, we showed very recently the involvement of TGIF, Smads and an SBE in the down- regulation by TGF-b of the human aryl hydrocarbon receptor ... in human plasma are drastically diminished in conditions of systemic inflammatory response, sepsis, and burn injuries [8,9]. As TGF-b 1 is secreted by activated macrophages [1...

Ngày tải lên: 31/03/2014, 23:20

... CB0006 anti-hTNF antibody and Dr Wim Buurman (University of Limburg, The Netherlands) for providing the hTNF ELISA. VA would like to thank Dr Dimitris Kontoyiannis for critical reading of the manuscript ... or onset of disease (data not shown). The ability of cells to adhere to the ECM is a critical deter- minant of cytoskeletal organization and cellular morphol- ogy [30], and of...

Ngày tải lên: 09/08/2014, 01:21

... conception, planning and design of the study, as well as the acquisition, analysis, and interpretation of data, and writing of the manuscript. PTC was involved in the acquisition of data, analysis and ... of participants per unit of time provided by the technician. A second analysis explored the variations due to the salary changes of the technician, since this is a major source...

Ngày tải lên: 09/08/2014, 10:23

... necessary resource for whole-genome comparative analysis of gene sequence evolution in a non-mammalian vertebrate lineage. To analyze basic molecular evolutionary processes during avian evolution, and ... largely conserved [7] and is characterized by a high degree of conserved syn- teny. In contrast to mammals, avian chromosomes show significant variation in size, with the karyotype...

Ngày tải lên: 09/08/2014, 20:22

... muscular variation and were presented in relation to their trajectory as superficial sensory branch trajectory coming from the ulnar nerve's dorsal cutaneous branch and a deep sensory branch trajectory coming ... ulnar nerve branches fitted Kaplan's variation type 4 according to Hankins et al. [12]. Kaplan's accessory branch (considered a rare anatomic variant) together with ac...

Ngày tải lên: 10/08/2014, 10:20

... Department, Cantonal Hospital Lucerne, Switzerland Email: Philipp Honigmann* - philipp.honigmann@zgks.ch; Alexander Walz - alexander.walz@zgks.ch; Christian Bussmann - christian.bussmann@ksl.ch; ... peribronchial and infiltrating S100 positive tumor supporting the Schwann cell origin theory with very low growth rate of 2% and a size of 15 mm (Figure 3). About 130 cases of pulmonary occ...

Ngày tải lên: 10/08/2014, 10:20

... University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. 2 Department of Orthopaedic Surgery, Kyorin University, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan. 3 Department of Diagnostic ... publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Author details 1 Department of O...

Ngày tải lên: 11/08/2014, 00:23