... statistically significantdifferences between control (con) culture and cultures with IL-7, with IL-4 or with IL-7 and IL-4. Significant differences between the cytokinetreatments are indicated ... Institute, Kenilworth,NJ, USA), or with or without IL-7 and IL-4 (both 10 ng/ml).Cytokine analysisIFN-γ and IL-4 production were analyzed by ELISA uponcostimulation with CD3/CD28 and cytokines ... statistically significant differences between RA patients and healthy controls; *P < 0.05, **P < 0.01, statistically significant differencesbetween control and cytokine-treated cultures.HealthyRA%...