Báo cáo y học: " Evidence for intelligent (algorithm) design" doc
Báo cáo y học: " Evidence for intelligent (algorithm) design" doc
... Stanford University, Stanford CA 94305, USA. †Department of Developmental Biology,Stanford University, Stanford CA 94305, USA. ‡Department of Computer Science, Stanford University, Stanford ... Genome Biology 2006, 7:322commentreviewsreportsdeposited researchinteractionsinformationrefereed researchMeeting report Evidence for intelligent (algorithm) designBalaji ... theobserved dynamics to yield insight into aspects of proteinbiochemistry, such as cooperativity or macromolecularassembly. To this end, Tsung-Han Chiang (National Univer-sity of Singapore,...
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Báo cáo Y học: Evidence for general stabilization of mRNAs in response to UV light pdf
... lM) as indicated. Cytoplasmic lysates were assayed for GFP-MKK62Eprotein by Western blot,and for activation of the p38 MAP kinase/MK2 pathway by in vitro kinase assays with recombinant HSP27 ... plasmid for puromycin resistance, and stable transfectants selectedby culture in 1 lgÆmL)1puromycin. Myc-tagged HuRwas expressed with the plasmid pTet-Myc-over-HuR [27](a gift from A B. Shyu, ... kindly donated by H. Furneaux, University ofConneticut Health Center, Farmington, CT, USA, andG. Dreyfuss, University of Pennsylvania School ofMedicine, Philadelphia, PA, USA, respectively.Transfections...
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Báo cáo y học: "Evidence for early disease-modifying drugs in rheumatoid arthritis" pps
... frequent withcombination therapy at 2 years. Subsequent analysesfound that delaying DMARD therapy by only a few monthsdecreased the ability of the monotherapy to induce remis-sion [20]. The ... in early RA. Three years afterthe study ended, early DMARD therapy still resulted inless pain and disability.The report by Verstappen and colleagues [3] shows thatthe situation is very complex. ... strong support for early DMARD therapy. Neverthe-less, the benefits of early DMARDs became less obviouswith time. By 5 years patients receiving early DMARDshad similar disease activity and comparable...
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Báo cáo y học: "Evidence for chronic, peripheral activation of neutrophils in polyarticular juvenile rheumatoid arthritis" pdf
... patient)Gene Microarray Polymerase chain reactionDirectional matchCD74 5.9 1.7 YesPTGS2 7.6 2.2 YesV-FOS 10.6 2.3 YesNFKB1A 19.1 7.2 YesSCYA3L1 10.8 23.7 YesSCYA4 12 27.3 YesAvailable online ... cells wereremoved from the granulocytes by hypotonic cell lysis as rec-ommended by the manufacturer, and granulocytes wereplaced immediately in Trizol reagent for RNA purification.Plasma was ... supportthe hypothesis that the defect may be primary. In earlier stud-ies of JRA using whole blood buffy coats, we demonstratedboth by discriminant function analysis and connectivity analy-ses...
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Báo cáo y học: " Evidence for natural antisense transcript-mediated inhibition of microRNA function" ppsx
... revealed by RACE and high-density tiling arrays. Genome Res 2005, 15:987-997.3. Gustincich S, Sandelin A, Plessy C, Katayama S, Simone R, Lazarevic D, Hayashizaki Y, Carninci P: The complexity of ... 50°C for 2 minutes then 95°C for 10 minutes then 40 cycles of 95°C for 15 s and 60°C for 1 minute. The results are based on cycle threshold (Ct)values. Differences between the Ct values for experimen-tal ... Biology 2010, 11:R56http://genomebiology.com/2010/11/5/R56Page 12 of 13Out of this list, 99 pairs were deleted from any analysesdescribed in this study, as we could not verify that theyindeed...
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Báo cáo y học: " Evidence for genetic association of RORB with bipolar disorder" pptx
... Biology, Indiana University, Bloomington, IN, USA, 3Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA, 4Laboratory of Neurophenomics, Department of Psychiatry, Indiana ... Fur-ther evidence for family-genetic risk factors in attention def-icit hyperactivity disorder. Patterns of comorbidity inprobands and relatives in psychiatrically and pediatricallyreferred ... psychotic dis-orders: A novel approach for deconstructing and quantitat-ing psychiatric phenotypes. Am J Med Genet B NeuropsychiatrGenet 2006, 141(6):653-662.46. Niculescu AB: Polypharmacy...
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Báo cáo y học: " Evidence for preferential copackaging of Moloney murine leukemia virus genomic RNAs transcribed in the same chromosomal site" ppt
... results of this study provide evidence that the Mo-MuLV genome is mainly formed from RNA moleculessynthesized on the same DNA-provirus. This property ofMo-MuLV may explain why only small subpopulations ... human immunodefi-ciency virus type 1 genome. J Virol 2000, 74:1234-1240.12. Yu H, Jetzt AE, Ron Y, Preston BD, Dougherty JP: The nature ofhuman immunodeficiency virus type 1 strand transfers. ... Central yours — you keep the copyrightSubmit your manuscript here:http://www.biomedcentral.com/info/publishing_adv.aspBioMedcentralRetrovirology 2005, 2:3 http://www.retrovirology.com/content/2/1/3Page...
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Báo cáo y học: " Evidence for horizontal transfer of a secondary metabolite gene cluster between fungi" potx
... secondary metabolism gene cluster of M. griseacomprises 15 genes: ACE1 and SYN2 are PKS-NRPS hybridgenes; RAP1 and RAP2 code for enoyl reductases; CYP1-CYP4 for cytochrome P450 monoxygenases; ... involved hyphal fusion between species, or endocytosis.Our inference of HGT is valid only if the Sordariomycete andEurotiomycete clades are monophyletic as shown in Figure 1,but their monophyly is ... cluster. Phylogenetic trees show clearly that in M.grisea RAP2 is a paralog of RAP1, CYP3 is a paralog of CYP2,CYP4 is a paralog of CYP1, and SYN2 is a paralog of ACE1(Figure 2a-d). Notably, in...
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Báo cáo y học: "Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria" pps
... chosen based on the proximity that representatives from A. tumefaciens have to genes.serCU Y UUUUGUUUCCCCCYYCURAU Y GCRRG Y Y5′YGYY Y YY Y TerminatorAAGCRYRYGCGCACGCCCACA5′RUUAGCAUGUGGG ... responsible for sensing a relevant metabo-lite, binding to the relatively small serC element, and dere-pressing translation. The PyrR protein performs a similarregulatory role for pyrimidine biosynthesis ... riboswitches.HomoserineO-succinyl-L-homoserineL-homocysteineCystathioninemetAO-acetyl-L-homoserinemetXmetZmetCmetBmetBmetHmetEmetKS-adenosyl-L-methionineL-methionineP2aP3P2P1AGARUUARUACGAGP4CAGUCACCGUGRC Y AACGCGU Y RRRCUGRAGCR Y AGACGGRR Y GGCCGCAG Y GRSAM-I5′ Y GGGA Y UUURCCR Y YRRUUGCRAAAAAGCUAAARRP1P25′SAM-ISAM-IICRSAM-II...
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Báo cáo y học: "Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals" ppt
... this effectmay in part be mediated by selection for mRNA stability.Notably, the preference for cytosine at synonymous sites canbe accounted for by such a process. Importantly, the observedsubstitutions ... (usually synonymous)should be preferentially paired with first and second sites(few and no synonymous sites, respectively). This would alsoprovide a buffer for mRNA structure against non-synony-mous ... geneSequence identifiers for each mouse gene.Click here for fileAdditional data file 6Ontology information for each mouse geneOntology information for each mouse gene.Click here for fileAdditional...
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