Báo cáo y học: " Evidence for intelligent (algorithm) design" doc

... Stanford University, Stanford CA 94305, USA. † Department of Developmental Biology, Stanford University, Stanford CA 94305, USA. ‡ Department of Computer Science, Stanford University, Stanford ... Genome Biology 2006, 7:322 comment reviews reports deposited research interactions information refereed research Meeting report Evidence for intelligent (algorithm) design Balaji ... the...

Ngày tải lên: 14/08/2014, 16:21

... l M ) as indicated. Cytoplasmic lysates were assayed for GFP-MKK6 2E protein by Western blot, and for activation of the p38 MAP kinase/MK2 pathway by in vitro kinase assays with recombinant HSP27 ... plasmid for puromycin resistance, and stable transfectants selected by culture in 1 lgÆmL )1 puromycin. Myc-tagged HuR was expressed with the plasmid pTet-Myc-over-HuR [27] (a gift from A B...

Ngày tải lên: 31/03/2014, 08:20

... frequent with combination therapy at 2 years. Subsequent analyses found that delaying DMARD therapy by only a few months decreased the ability of the monotherapy to induce remis- sion [20]. The ... in early RA. Three years after the study ended, early DMARD therapy still resulted in less pain and disability. The report by Verstappen and colleagues [3] shows that the situation is very complex....

Ngày tải lên: 09/08/2014, 01:23

... patient) Gene Microarray Polymerase chain reaction Directional match CD74 5.9 1.7 Yes PTGS2 7.6 2.2 Yes V-FOS 10.6 2.3 Yes NFKB1A 19.1 7.2 Yes SCYA3L1 10.8 23.7 Yes SCYA4 12 27.3 Yes Available online ... cells were removed from the granulocytes by hypotonic cell lysis as rec- ommended by the manufacturer, and granulocytes were placed immediately in Trizol reagent for RNA purification. Pla...

Ngày tải lên: 09/08/2014, 08:22

... revealed by RACE and high-density tiling arrays. Genome Res 2005, 15:987-997. 3. Gustincich S, Sandelin A, Plessy C, Katayama S, Simone R, Lazarevic D, Hayashizaki Y, Carninci P: The complexity of ... 50°C for 2 minutes then 95°C for 10 minutes then 40 cycles of 95°C for 15 s and 60°C for 1 minute. The results are based on cycle threshold (Ct) values. Differences between the Ct va...

Ngày tải lên: 09/08/2014, 20:22

... Biology, Indiana University, Bloomington, IN, USA, 3 Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA, 4 Laboratory of Neurophenomics, Department of Psychiatry, Indiana ... Fur- ther evidence for family-genetic risk factors in attention def- icit hyperactivity disorder. Patterns of comorbidity in probands and relatives in psychiatrically and pediatrically r...

Ngày tải lên: 11/08/2014, 17:20

... results of this study provide evidence that the Mo- MuLV genome is mainly formed from RNA molecules synthesized on the same DNA-provirus. This property of Mo-MuLV may explain why only small subpopulations ... human immunodefi- ciency virus type 1 genome. J Virol 2000, 74:1234-1240. 12. Yu H, Jetzt AE, Ron Y, Preston BD, Dougherty JP: The nature of human immunodeficiency virus type 1 strand...

Ngày tải lên: 13/08/2014, 13:20

... secondary metabolism gene cluster of M. grisea comprises 15 genes: ACE1 and SYN2 are PKS-NRPS hybrid genes; RAP1 and RAP2 code for enoyl reductases; CYP1-CYP4 for cytochrome P450 monoxygenases; ... involved hyphal fusion between species, or endocytosis. Our inference of HGT is valid only if the Sordariomycete and Eurotiomycete clades are monophyletic as shown in Figure 1, but their monoph...

Ngày tải lên: 14/08/2014, 08:20

... chosen based on the proximity that representatives from A. tumefaciens have to genes. serC U Y UUUU GUUUCCCCCYYCURAU Y GC R R G Y Y 5′ YG YY Y YY Y Terminator A AG C RY RY GC GC AC GC C CA C A 5′ RU UA GC AU GU GGG ... responsible for sensing a relevant metabo- lite, binding to the relatively small serC element, and dere- pressing translation. The PyrR protein performs a similar r...

Ngày tải lên: 14/08/2014, 14:22

... this effect may in part be mediated by selection for mRNA stability. Notably, the preference for cytosine at synonymous sites can be accounted for by such a process. Importantly, the observed substitutions ... (usually synonymous) should be preferentially paired with first and second sites (few and no synonymous sites, respectively). This would also provide a buffer for mRNA structure...

Ngày tải lên: 14/08/2014, 14:22