Báo cáo y học: "Transcriptional control of dendritic patterning in Drosophila neurons" docx

... functions of each transcription factor group in dendritic patterning of type I DA neurons in the Drosophila peripheral nervous system. Subtypes of DA neurons have simple and stereotyped branching patterns ... phenocopy of the RNAi phenotype, validating the accuracy of the approach. Analysis of the mutant flies revealed that some of the candidate genes are also involved...

Ngày tải lên: 14/08/2014, 16:21

... the facilitatory effect of tidal inspiration on genioglossus pre activation tended to be higher in OSAS than in controls also with a preferential increase in UA muscles excitability during inspiratory loading ... excitability changes Facilitatory maneuvers modify TMS responses by increas- ing synaptic excitability at either the motor cortex and/or the spinal motoneurons [29] (or, in...

Ngày tải lên: 12/08/2014, 14:20

... negatively regulate integration [116,117]. This is seen with both integrating and non- integrating virus, thereby effectively regulating superin- fection at the level of integration rather than entry [117]. ... that seen in productive infec- tion using wild type virus. Thus, the activity of Nef was not linked to integration in regards HLA class I modula- tion, a finding confirmed in...

Ngày tải lên: 13/08/2014, 01:21

... in 2003. The lines were inbred by 20 generations of full-sib inbreeding to create 340 inbred lines. Locomotor reactivity for each of the inbred lines was measured by randomly assigning the lines ... reactivity than the control line. Of these genes, four have been previously implicated to affect activity: muscle- blind mutants are paralytic [36]; Amphiphysin [37] and Cysteine string...

Ngày tải lên: 14/08/2014, 08:20

... and the induction of ethanol tolerance [30]. Induction of ethanol tolerance was completely abolished in flies carrying both null mutations in hang and in the gene encoding tyramine β-hydroxylase ... human orthologue RAB11 family interacting protein 4 (RAB11FIP4)). Alcohol-induced fatty acid biosynthesis is well documented in heavy drinkers and leads to alcohol induced fatty liver...

Ngày tải lên: 14/08/2014, 17:22

... termination and increased mRNA stabi- lity by RNA-binding proteins are involved in the regu- lation of gene expression in eukaryotes and their viruses [135,136]. A thorough investigation of these processes ... modified by the presence of a hydroxy- methylated, glucosylated moiety at cytosine position 5. This modification places a large, bulky group within the major groove, making it...

Ngày tải lên: 12/08/2014, 02:20

... played by specific domains in the corresponding transcription factors during in vivo erythroid and megakaryocyte development. Erythroid Kruppel-like factor (EKLF) This zinc finger protein plays ... Whang- Peng,J.&Haynes,B.F.(1984)Conversionofastemcellleukemia from a T-lymphoid to a myeloid phenotype induced by the ade- nosine deaminase inhibitor 2¢-deoxycoformycin. Proc. Natl Acad. Sci....

Ngày tải lên: 08/03/2014, 22:20

... Wathelet 1 1 Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati; 2 Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA Virus infection ... functionally unable to Correspondence to M. G. Wathelet, Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, 231 Al...

Ngày tải lên: 17/03/2014, 10:20

... Aec2 contain genes that control development of SjS. In the present study, the investigators produced recombinant inbred lines by crossing the C57Bl/6 and C57Bl/6.NOD- Aec1Aec2 strains. A recombinant inbred ... exocrino- pathy in the NOD mouse and by reducing one of these regions considerably, Nguyen et al. in a recent issue of Arthritis Research and Therapy propose candidate gen...

Ngày tải lên: 09/08/2014, 01:22

... JA, Benbow U, Vincenti MP, Sporn MB, Brinck- erhoff CE: A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflamma- tory cytokines. Arthritis ... Griswold DE: Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock...

Ngày tải lên: 09/08/2014, 03:24