Báo cáo y học: "The subcellular localization of the mammalian proteome comes a fraction closer" docx

... considering the many noteworthy efforts that are under way. One answer could be the great size and complex- ity of mammalian genomes, but we rather favor the explana- tion that it is more a problem of ... least partially present in the plasma membrane fraction, despite the fact that the majority of these have been reported to be present only on internal organelles. Care...

Ngày tải lên: 14/08/2014, 16:21

... days 6 t o 8 despite a constant rate of infusion. The concen- tration of any drug at a steady state is dependent only on its plasma clearance and the rate of infusion. Accordingly, the calculated ... MS and KTO were involved in the interpretation of data and review of literature. They also drafted and revised the manuscript. All authors read and approved the final ma...

Ngày tải lên: 11/08/2014, 11:23

... this case, the feeling of a mass in the throat without dysphagia was the only symptom of large pyriform sinus lipoma. The preferred method of treatment for laryngeal and hypopharyngeal lipogenic ... feeling of a mass in the throat without dysphagia was the only symptom of large pyriform sinus lipoma. Although the mass may be asymptomatic, it should be surgica...

Ngày tải lên: 25/10/2012, 10:51

... By the age of 8 years, the top of the frontal sinuses is at the level of the orbital roof, and by the age of 10 years, the sinuses extend into the vertical portion of the frontal bone. The ... extending above a line tangential to the supraorbital margin. Frontal sinus aplasia was also defined by an oval-shaped sinus with the lateral margin medial to a...

Ngày tải lên: 25/10/2012, 11:04

... to the antibody [18]. Conventional pepscan analysis however, does not allow easy analysis of the contribution of the carbohydrate portion. To assess the involvement of carbohydrates in antibody ... Selective presat- uration of the protein was achieved by a train of 40 Gaussian shaped pulses of 50 ms length, each separated by a 1 ms delay, leading to a total saturat...

Ngày tải lên: 21/02/2014, 15:20

... Tewari, Y. B. & Goldberg, R.N. (2000) A thermo- dynamic study of the hydrolysis of 1-glutamine to (1-glutamate + ammonia) and of 1-asparagine to (1-aspartate + ammonia). J. Chem. Thermodynamics ... in the presence of GTP, UTP and the nonhydrolyzable ATP analog ADPNP [8]. Furthermore, it was shown that the fold activation of the glutaminase activity by GTP was simila...

Ngày tải lên: 21/02/2014, 15:20

... (2001) Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibi- lities for an enzyme hydrolyzing anandamide, 2-arachidonoylgly- cerol, palmitoylethanolamide, and oleamide. ... anandamide and 2-arachidonoylglycerol (2-AG), the cannabinoid CB 1 and CB 2 receptors, and one of the enzymes mostly responsible for endocannabinoid hydrolysis, the fatty acid amide hydro...

Ngày tải lên: 22/02/2014, 07:20

... of 400 m M NaCl (data not shown). Gas liquid chromatography analysis of the reduced glucans after methanolysis and silylation reactions revealed that glucose could account for all the carbohydrate ... substituents, analyzed by MALDI mass spectrometry and purified by high-performance anion-exchange chromatography. Methylation analysis revealed that this glucan is linked by 17 1,2 glycos...

Ngày tải lên: 17/03/2014, 17:20

... Itoh, M., Ishii, Y. , Arakawa, T., Hara, A. , Fukunishi, Y. , Konno, H., Adachi, J., Fukuda, S., Aizawa, K., Izawa, M., Nishi, K., Kiyo- sawa,H.,Kondo,S.,Yamanaka,I.,Saito,T.,Okazaki ,Y. , Gojobori, ... human and murine cDNA panel. In the lower panel the amplification of a GADPH control fragment after 26 cycles of PCR is shown to verify that similar amounts of cDNA had been pres...

Ngày tải lên: 23/03/2014, 21:20

... 1041– 1050. 29. Sato, C., Kim, J H., Abe, Y. , Saito, K., Yokoyama, S. & Kohda, D. (2000) Characterization of the N-oligosaccharides attached to the atypical Asn-X-Cys sequence of recombinant human epi- dermal ... of adapter proteins by the phos- phorylated receptors can stimulate the Ras signaling pathway, leading to the activation of extracellular signal- regulated pr...

Ngày tải lên: 24/03/2014, 03:21