Báo cáo y học: "PI3K signaling and miRNA expression during the response of quiescent human fibroblasts to distinct proliferative stimuli" pdf

... R42 Research PI3K signaling and miRNA expression during the response of quiescent human fibroblasts to distinct proliferative stimuli Jian Gu and Vishwanath R Iyer Address: Section of Molecular Genetics and ... G1 transition to stimulate the MAP kinase (ERK) pathway, c- Myc, and the PI3K pathway [18]. We observed altered expres- sion of regulatory f...

Ngày tải lên: 14/08/2014, 16:21

... consist of revision surgery and spacer exchange. On the other hand, asymptomatic fractures are found in the middle or lower part of the spacer stem (Figure 6) and usually require no further ... debris have to be removed from the femoral canal during the later prosthesis reimplantation, and that during removal of the prosthesis stem osseous defects might occ...

Ngày tải lên: 26/10/2012, 09:53

... behavioral responses to trauma may be specific to the type of trauma experienced. Compared with other types of trau- mas, the experience of combat has also been shown to be related to both distinct PTSD symptom ... and a number of theories have been posited to e xplain the relationship, including the self- medication hypothesis, the sensation-seeking hypothesis...

Ngày tải lên: 11/08/2014, 16:22

... ‘’cyto kine hypoth- esis’’ has been developed that associates the dysreg ulation of the immuno-inflammatory system with the aetiology and the pathophysiology of MDD. Recently, a larger panel of ... site, study nurses were trained in the appli- cation of SOPs by staff members of the Dept. of Psy- chiatry and Psychotherapy, UMCM. Study nurses of trial sites are sup...

Ngày tải lên: 11/08/2014, 16:23

... Immunology 1998, 10:711-717. ˆ Y ˆ y ˆ y ˆ y ˆ y ˆ y ˆ y ˆ y ˆ y fy y n dy y nn jj j n (,) (,).= () = ∑ 1 27 1 ˆ y ˆ y Dpydyy nnn y n = () ∑ ()(,). 28 ˆ Y ˆ Y ˆ Y ˆ Y ˆ Y ˆ Y ˆ y RD IYY pyy pypyydyy ... undereducated and underemployed. They not only have to face disclosure issues, but also issues related to race and poverty. Daily, they stack...

Ngày tải lên: 13/08/2014, 16:21

... Center, Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, Prague, Czech Republic. Authors’ contributions AF, NMvM and MN conceived and designed the study. AF, ... and maturation inhibitors may seem unlikely, but the co-evolution of protease and its substrate, Gag, during protease inhibitor therapy, could potentially...

Ngày tải lên: 13/08/2014, 01:21

... or the depletion of mycolic acids in the cell wall. ey are now investigating whether pulsatile expression of catalase G relates inversely to the ability of individual cells to survive the ... manipulated by titrating the levels of this cyclin. By constructing a minimal cell- cycle oscillator dependent on the activity of a single cyclin-CDK, these groups have effe...

Ngày tải lên: 09/08/2014, 20:21

... on signaling mechanisms held recently in London under the auspices of the charity Cancer Research UK looked at cell -signaling pathways in relation to cancer and how they may point to new therapeutic ... activates Wnt signaling, whereas Gsk3β in the cytosol has the opposite effect. The Ras-activated MAP kinase (MAPK) module is part of many signaling pathways, and R...

Ngày tải lên: 14/08/2014, 07:22

... an auditory phantom percept related to tonic and burst hyperactivity of the auditory system. Two parallel pathways supply auditory information to the cerebral cortex: the tonotopically organised ... related to reorganization [2] and hyperactivity[3] of the auditory system. The auditory system consists of two main parallel pathways supplying auditory information...

Ngày tải lên: 08/08/2014, 16:23

... ges- tures and attempts, may become a way of attempting to cope with this pain. The best way to prevent suicide is to learn what is causing the distress, the tension and the anguish. Another key factor ... was performed during one of these days in order to "change things" and " ;to feel the pain in the body and not in the mind." It was a...

Ngày tải lên: 08/08/2014, 21:20