Báo cáo y học: "Intron gain and loss in segmentally duplicated genes in rice" docx

... an intron loss( es) (43 intron losses in total), one gene pair with a single gained intron, and four gene pairs in which both intron loss and gain were observed (6 intron losses and 4 intron gains). ... lost and gained intronsFigure 3 Distribution of the sizes of the lost and gained introns. Intron lengths were binned into 100 bp bins and the number of lost and gained...

Ngày tải lên: 14/08/2014, 16:21

... spe- cies-specific duplications in zebrafish outshines the number of retained WGD duplicates in this proteome. This explains why many genes of GOs resulting from WGDs are retained in excess in all species except ... signaling, and development after paleopolyploidy events as shown here and in previous studies, and the fact that in particular such genes are considered impo...

Ngày tải lên: 14/08/2014, 16:21

... containing three tandemly repeated type 2-like cystatin domains. Type 2 cystatins identified in higher animals include cystatins C, D, S, SA, and SN [2], but also the recently reported cystatin ... are readily secreted in mammalian [20] and insect [5] cells, respectively. Cystatin F is an unusual type 2 cystatin in that it is a glycoprotein [5,6], and it is known that many proteins...

Ngày tải lên: 21/02/2014, 01:21

... micro-injury, psychologically based increase in pain threshold, innately high pain threshold influencing decision to exercise vigorously, or other psycho- logical mechanisms. Musculoskeletal pain ... time. As pain and disability are linked, our findings add to the evidence that morbidity associated with aging can be reduced by partic- ipating in regular aerobic activity. Competing inter...

Ngày tải lên: 09/08/2014, 07:20

... from arginine into tryptophan. This amino acid change disrupts the binding of Lyp to an intracellular kinase, Csk, which can then no longer inactivate another kinase, Lck, that is involved in T-cell ... determined using enzyme-linked immunoassays. Genotyping was performed using an ABI PRISM 7900HT instrument and HLA-SE genes were identified using PCR sequence-specific primers. The 1858T...

Ngày tải lên: 09/08/2014, 07:20

... MMPs, proinflammatory cytokines and chemokines [13]. There is increasing evidence that SFs are key players in the pathogenesis of RA by invading and eroding hyaline cartilage. SFs, activated locally, ... growth factor, insulin-like growth factor-binding proteins), morpho- gens, enzymes, numerous cytokines and chemokines, inter- leukins, and so forth [52]. It can be hypothesized that...

Ngày tải lên: 09/08/2014, 14:20

... effect against arrhythmias has been attributed to estradiol which inhi- bits the release of inflammatory cytokines[21]. Estradiol is higher in newborn girls than in boys, which may explain why, in ... sustained and hemodynamically significant arrhythmias, shorter or more subtle rhythm disorders that may still reflect electrical instability of the myocyctes and a propensity to develo...

Ngày tải lên: 10/08/2014, 09:22

... thrombopoietin and erythropoie- tin might explain thrombocytosis in children with iron- deficiency anemia [8]. In our case, we observed a marked increase in the level of erythropoietin which declined ... c-mpl and the erythropoietin receptor. On the other hand, it has been suggested that erythropoietin and thrombopoietin can synergistically stimulate megakaryocyte proliferation ow...

Ngày tải lên: 11/08/2014, 23:21

... lesions involving <25% of the myocardium; 2, lesions involving 25% to 50% of the myocardium; 3, lesions involving 50% to 75% of the myocardium; and 4, lesions involving >75% of the myocardium. Statistics All ... and cell infiltration were extensive on day 7, with necrotic areas appearing more prominent. There were many lymphocytes and macrophages in and around the necrotic foc...

Ngày tải lên: 12/08/2014, 01:22

... therapy with LABA monotherapy worsens air- ways hyperresponsiveness, possibly by upregulating either aspects of the inflammatory response or mucin contain- ing cells and exacerbating distal airway ... CT (V TG )wasnotsignificantlydifferentamonganyofthe groups (data not shown). Mucin The number of airway epithelial cells containing airway mucin was greatest in the V and S groups and wa...

Ngày tải lên: 12/08/2014, 11:20