Báo cáo y học: "The Inferelator: an algorithm for learning parsimonious regulatory networks from systems-biology data sets de novo" pptx

... page) cspd1 tfbf VNG0424C VNG0703H 191 1 nirh AND nusa 98 AND illumination boa2 gamma 319 AND 388 AND cspd2 3 7 12 16 VNG0194H 25 49 50 55 71 79 tfbg 113 123 2 VNG0040C tbpe 19 24 29 67 VNG0066H 128 VNG5075C 263 VNG0039H AND rhl VNG0320H tfbb VNG1029C 59 170 283 kaic AND trh7 156 tbpd 89 219 416 423 432 449 4 5 8 gvpe2 28 oxygen 141 148 182 188 200 338 AND tbpc 210 6 phou prp1 arsr sirr 76 12...

Ngày tải lên: 14/08/2014, 16:21

... thank Christopher Maher and Arul Chinnaiyan for providing us with their RNA-seq data. Thanks to Lou Staudt for invaluable feedback on early versions of TopHat-Fusion, to Ryan Kelley for his indel- finding ... number of spanning reads and mate pairs reported by TopHat-Fusion and deFuse for ten previously reported fusion transcripts in the SKBR3 and MCF7 sample data. Kim and Salzberg...

Ngày tải lên: 09/08/2014, 23:20

... held May 15 th /16 th , 2010, Toronto, Canada and was cosponsored by CHAEN/RCAH, the Canadian Society of Allergy and Clinical Immunology, and the University of Calgary and was funded through an unrestricted ... receptor 2 antagonist (Icatibant) for hereditary angioedema type III attacks. Ann Allergy Asthma Immunol 2009, 103:448. 75. Frank MM, Gelfand JA, Atkinson JP: Hereditary angioedema...

Ngày tải lên: 08/08/2014, 21:20

... multisystem disorder, with acute renal failure, hypotension, sepsis, coagulopathy, encephalopathy and cerebral oedema [5,12]. Decisions about management and prognosis must be made quickly in order ... specificity in identifying patients with poor prognosis, but they are of low sensitivity and may fail to identify a proportion of patients who will die [13]. In one study [16], the Acute Physiol...

Ngày tải lên: 12/08/2014, 18:21

... hydrazone class as effective antiproliferative agents II. The mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone. Blood 89, 3025–3038. 42. ... was obtained from Gibco BRL. DFO was obtained from Novartis Pharmaceutical Co. Pyridoxal isonicotinoyl hydrazone (PIH) and its analogue, 2-hydroxy-1-naphthylal- dehyde i...

Ngày tải lên: 08/03/2014, 22:20

... mean and on the variance of  J y (N b )underboth assumptions. Thanks to the result of Corollary 1, we can deduce the following result. Corollary 2. The asymptotical mean and variance of  J y , ... N  y  u 2  = cum  y  u 1 + N  , y ∗  u 1  , y ∗  u 2 + N  y  u 2  + E  y  u 1 + N  y ∗  u 1  E{ y ∗  u 2 + N )y  u 2  + E  y  u 1 + N  y  u 2 ...

Ngày tải lên: 22/06/2014, 06:20

... group. HAD-A, Hospital Anxiety and Depression Scale-Anxiety; HAD-D, Hospital Anxiety and Depression Scale-Depression. Annals of General Psychiatry 2009, 8:9 http://www.annals-general-psychiatry.com/content/8/1/9 Page ... for suicide independent of DSM-III-R Axis I disorder. Case-con- trol psychological autopsy study in Northern Ireland. Br J Psy- chiatry 1999, 175: 175-179. 54. Nakane C: Ja...

Ngày tải lên: 08/08/2014, 23:21

... 38:170-187. 4. Awata T, Kuzuya T, Matsuda A, Iwamoto Y, Kanazawa Y: Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia ... ethylenediamine tetraacetic acid-anticoagulated tubes and DNA was extracted using standard methods. A Taqman SNP genotyping assay was designed for rs1990760 by Applied Biosyste...

Ngày tải lên: 09/08/2014, 10:20

... statistical analysis. We consider model 6 of Verbeke and Molenberghs which is a typical random coefficient model for longitudinal data analysis with an intercept and a linear slope, and can be written as y ijk = ... Growth data from Pothoff and Roy [28] with the 9 missing values de ned by Little and Rubin [19]: see also Verbeke and Molenberghs [33] for a detailed analysis. Here 1s...

Ngày tải lên: 09/08/2014, 18:21

... accomplished by RNA interference against Dfz2 in an fz mutant background, by analysis of chromosomal deficiencies that delete Dfz2 (see Table 1), and by identifying mutations in Dfz2 and crossing ... Pathway specificity by the bifunctional receptor Frizzled is determined by affinity for Wingless. Molecular Cell 2000, 6:117-126. An important paper showing that ligand affinity plays a rol...

Ngày tải lên: 09/08/2014, 20:20