Báo cáo y học: "The success (or not) of HUGO nomenclature" pot

... only a question of time for these genes to acquire new synonyms. Furthermore, highly refer- enced genes are cited notably more often by unofficial gene names. For example, in 2004, only 38% of ... predominantly by following HUGO, whereas scarcely cited genes more often followed the standards (54% in 2004). The tendency to improve the situation by replacing aliases in favor of HUGO of...

Ngày tải lên: 14/08/2014, 16:21

... likely to be easy to both genotype and sequence. The sensitivity of SNP and indel detection in repetitive or copy-number-variable regions will be lower. Finally, a non-trivial proportion of any ... and Applied Biosystem’s SOLiD [5] systems - but no explicit comparison of the two versions has yet been published. Minireview The promise and reality of personal genomics Bryndis Yngva...

Ngày tải lên: 09/08/2014, 20:20

... phenotypes of the AP-2 mutants generated so far have precluded an analysis of the roles of AP-2 transcription factors in adult tissues. We and others are currently exploit- ing the power of conditional ... activity is modulated by protein kinase A-mediated phosphorylation. FEBS Lett 1999, 444:27-31. 23. Park K, Kim KH: The site of cAMP action in the insulin induc- tion of gene exp...

Ngày tải lên: 14/08/2014, 16:20

... hyperinsulinaemic hypoglycaemia of infancy is an hereditary disease char- acterized by inappropriately high levels of insulin release and hypoglycaemia in children at birth. It is hypothesized that deletion of the ... Potentially, this has clinical ramifications as a number of mutations in persistent hyperinsulinaemic hypoglycaemia of infancy [12] cluster in this domain of the prot...

Ngày tải lên: 31/03/2014, 08:20

... may truly learn whether or not to dose. Abbreviations AKI, acute kidney injury; ARF, acute renal failure; HES, hydroxyethyl starch; RIFLE, risk, injury, failure, loss, and end-stage kidney ... with low volume hydroxyethylstarch 130 kDa/0.4 is not associated with acute kidney injury. Crit Care 2010, 14:R40. 2. Sakr Y, Payen D, Reinhart K, Sipmann FS, Zavala E, Bewley J, Marx G, Vincent .....

Ngày tải lên: 13/08/2014, 20:21

Ngày tải lên: 13/08/2014, 21:21

... Pungerc ˇ ar 2 1 Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia; 2 Department of Biochemistry and Molecular Biology and 3 Mass ... presynaptic membrane [6], after which they are presumably endocytosed. In the nerve cell, they may inhibit the recycling of synaptic vesicles by binding to certain targ...

Ngày tải lên: 31/03/2014, 08:20

... occu- pancy. The secretion of cytokines from lymphocytes, par- ticularly Th2 cells, appears to be central to the establishment and maintenance of an allergic inflamma- tory response. It is of interest ... allergic rhinitis trial. Pediatr Allergy Immunol 2005, 16:267-75. 10. Potter PC: Efficacy and safety of levocetirizine on symptoms and health-related quality of life of children...

Ngày tải lên: 08/08/2014, 21:20

... cells do not rely solely on glycolysis but also maintain an active TCA cycle, which entails a far greater rate of reduction (and hence reoxidation) of NAD. This may be possible only by reversing ... Complex II’s, they would be expected to respond similarly to any long-term intervention. That they do not suggests that much of the NADH produced by the TCA cycle may be diverted out of th...

Ngày tải lên: 17/03/2014, 23:20

... membrane insertion of colicin A. Biochemistry 31, 7294–7300. 28. Kasahara, K., Watanabe, Y. , Yamamoto, T. & Sanai, Y. (1997) Association of Src family tyrosine kinase Lyn with ganglioside GD3 ... the endo- cytic pathway [14]. In a further study on lipid rafts, analysis of the dynamic movement of intracellular rafts, for instance raft assembly and raft trafficking, is necessary a...

Ngày tải lên: 23/03/2014, 21:20