Báo cáo y học: "Systems biology of gene regulation fulfills its promise" ppsx
Báo cáo y học: "Systems biology of gene regulation fulfills its promise" ppsx
... Genome Biology 2006, 7:316 comment reviews reports deposited research interactions information refereed research Meeting report Systems biology of gene regulation fulfills its promise Adrienne ... occupancy of RNA polymerase II (PolII), Bing Ren (University of California, San Diego, USA) presented data from a large ChIP-chip study of five types of mouse tissue. He showed...
Ngày tải lên: 14/08/2014, 16:21
Báo cáo y học: " Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease" pptx
... diagnosis of COPD is based on the presence of typical symptoms of cough and shortness of breath, together with the presence of risk factors, and is confirmed by spirome- try. A variety of methods ... 2008, 54(2):262-273. 120. Yarden Y: Biology of HER2 and its importance in breast can- cer. Oncology 2001, 61(Suppl 2):1-13. 121. Kirschner MW: The meaning of systems biology...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps
... Street; University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. ¥ Department of Genetics, School of Medicine, Curie Boulevard; University of Pennsylvania, Philadelphia, Pennsylvania 19104, ... development of bioinformatic and systems biology approaches [45,46]. Genome Biology 2008, 9:R53 http://genomebiology.com/2008/9/3/R53 Genome Biology 2008, Volume 9, Issue 3...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "Microarray analysis of gene expression in lupus" ppt
... microarray system used was an Affymetrix U95A GeneChip (Affymetrix, Santa Clara, CA); 4566 genes were analyzed. Four healthy donors of PBMC were studied. † The microarray system used was an Affymetrix ... signatures in sys- temic lupus erythematosus blood. J Exp Med 2003, 197:711- 723. 6. Han GM, Chen SL, Shen N, Ye S, Bao CD, Gu YY: Analysis of gene expression profiles in human system...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: " Taking stock of gene therapy for cystic fibrosis" pdf
... http://respiratory-research.com/content/1/2/078 commentary review reports primary research models that successful gene therapy for cystic fibrosis requires only partial gene correction. Gene Ther 1996, ... the efficiency of gene transfer, but questions relating to the level of efficiency needed and the target cell population also need addressing. The key problem of efficiency ca...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: " A model of gene-gene and gene-environment interactions and its implications for targeting environmental " doc
... define G xy as the conditional probability P(relative is in genotypic risk category y| proband is in genotypic risk category x). Similarly, define E xy as the conditional proba- bility P(relative ... of genetic differences in determin- ing the risk of some conditions (for example, lung can- cer); (ii) the complexity of gene- gene and gene- environment interactions and/or lack of...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "Mouse maps of gene expression in the brain" pot
... The advantage of using the BAC as a cloning vector is that it can carry as much as 200 kb of genomic DNA - typically enough to include most, if not all, of the appropriate regulatory elements of the gene. ... be key to understanding the function and development of circuits in the brain and for genetic manipulation of circuit elements. This level of analysis will be critical to...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: "The determinants of gene order conservation in yeasts" pdf
... Kruglyak S, Tang H: Regulation of adjacent yeast genes. Trends Genet 2000, 16:109-111. 22. Byrne KP, Wolfe KH: Visualizing syntenic relationships among the hemiascomycetes with the Yeast Gene ... to explain patterns of conservation or not of gene pairs in general, it explains very little of the conservation of gene order (just one pair) and most conservation of synteny ha...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "The rarity of gene shuffling in conserved genes" pptx
... gene Aats-tyr, a tyrosyl-tRNA synthetase [36]. This gene is a likely recombination product of a predicted worm methionyl-tRNA synthetase gene mrs-1 [37] and a second worm gene Y1 05E8A.19 of unknown ... identifies only duplications of single-copy genes in the reference species. Multicopy genes may undergo duplication more frequently. We may thus have underestimated the number...
Ngày tải lên: 14/08/2014, 14:21
Báo cáo y học: "The biology of genomes: sequence gives way to function" ppsx
... the meeting ‘The Biology of Genomes’, Cold Spring Harbor, USA, 11-15 May 2005. This year’s Cold Spring Harbor meeting ‘The Biology of Genomes’ presented an eye-opening snapshot of how far the field ... understanding of coding transcripts, but with a discouraging number of transcripts of unknown function (TUFs), many of which are not polyadenylated. If anything, the data reve...
Ngày tải lên: 14/08/2014, 14:22