Báo cáo y học: "Stem cells in the genomic age" docx
Báo cáo y học: "Stem cells in the genomic age" docx
... transferred into an oocyte or fused with an ES cell, the
underlying mechanisms remain obscure. Using the ES fusion
system, Smith has found an unexpected role for the homeo-
domain-containing protein Nanog ... model system than mice in certain fields,
particularly neuroscience, and progress has been greatly
hampered by our inability to derive rat ES cells. Shinohara
hinted that he was...
Báo cáo y học: "Dendritic cells: In the forefront of immunopathogenesis and vaccine development – A review." doc
... reactive T lymphocytes, they will be deleted
indicating that DCs play a critical role in this process.
Moreover, in the cortical area of the thymus, although
macrophages phagocytize dying T cells which ... well as the skin
in order to be delivered specifically to DC subsets in vivo
(Figure 5).
The Peyer's patch is the primary mucosal site for antigen
processing in...
Báo cáo y học: " Review Cells of the synovium in rheumatoid arthritis" ppsx
... maintenance of the
proinflammatory cytokine cascade.
Role played by B cells as antigen-presenting
cells in rheumatoid arthritis
B cells actively participate in an autoimmune process through
interaction ... clinical disease activity, thereby enhancing
our understanding of the role played by B cells in human
disease.
Competing interests
The authors declare that they have no...
Báo cáo y học: " Review Cells of the synovium in rheumatoid arthritis" pot
... that
supply the arterial wall, and to the draining lymph nodes. In
support, DC can be detected between smooth muscle cells
in the medial layer of vessels. They are markedly increased in
media underlying ... http://arthritis-research.com/content/9/4/219
Abstract
Dendritic cells are the major antigen-presenting and antigen-
priming cells of the immune system. We review th...
Báo cáo y học: "Review Cells of the synovium in rheumatoid arthritis" pot
... in the inflamed synovium as a result of the influx
of inflammatory cells from the circulation and synovial cell hyperplasia. The upregulation of proinflammatory cytokines produced primarily in ... have
primary roles in the inflammatory and catabolic processes in
the joint, they may also promote cartilage damage, directly or
indirectly. Despite the clinical success of a...
Báo cáo y học: "Review Cells of the synovium in rheumatoid arthritis" ppsx
... TNF-R75 in the
rheumatoid synovial membrane: TNF receptors are localized
preferentially in the lining layer; TNF-alpha is distributed
mainly in the vicinity of TNF receptors in the deeper layers.
Scand ... indicated in Tables 4 and 5.
Interleukin-6
IL-6 is the most strikingly elevated cytokine in RA, especially
in the synovial fluid during acute disease [75]. The a...
Báo cáo y học: " A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis" doc
... IL-17
+
cells in the I/I genotype culture, as shown in the top
row of Figure 3A, compared to the suppression of IL-17
+
cells in the V/V genotype culture, shown in the bottom
row.Inthesecultures,themajorityofIL-17
+
cells ... variant of the human IL-4 receptor α-chain in IgE synthesis.
J Immunol 1999, 162:1227-1231.
29. Yabiku K, Hayashi M, Komiya I, Yamada T, Kinj...
Báo cáo y học: "Mast cells are the main interleukin-17-positive cells in anti-citrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium" pps
... other Th17-associated cytokines, play a prominent role in the inflamed
synovium by perpetuating the inflammatory milieu observed in arthritis [6]. Interestingly,
Concentrations of IL-17A in ... study, the cell types that did express IL-17 were found to be
mainly mast cells in one study.[9] However, the other study identified them as being
mainly neutrophils and neutrop...
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... bipolar disorder in the
general population are likely receiving even less medical
care. The significance of this finding is that the psychiatrist
may be the only physician caring for these patients ... portacaval shunting, thereby decreasing first pass
metabolism; decrease in quantities and affinity of plasma
proteins, thereby increasing free-drug levels; increase in
volume of d...